SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ihu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTV_A_TESA500_1
(17
BETA-HYDROXYSTEROID
DEHYDROGENASE TYPE 1)		 3ihu TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Cupriavidus
pinatubonensis) 		4 / 8 VAL A 192
LEU A 147
SER A 120
VAL A 121
 None
 1.21A 1jtvA-3ihuA:
undetectable		 1jtvA-3ihuA:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3ihu TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Cupriavidus
pinatubonensis) 		3 / 3 VAL A  92
ALA A  93
HIS A 207
 None
 0.73A 1q23G-3ihuA:
undetectable		 1q23G-3ihuA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3ihu TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Cupriavidus
pinatubonensis) 		3 / 3 VAL A  92
ALA A  93
HIS A 207
 None
 0.79A 1q23L-3ihuA:
undetectable		 1q23L-3ihuA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_2
(TRANSTHYRETIN)		 3ihu TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Cupriavidus
pinatubonensis) 		4 / 8 LEU A 156
THR A 105
LEU A 148
VAL A 192
 None
 1.00A 1sn5C-3ihuA:
undetectable		 1sn5C-3ihuA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_1
(RETINOIC ACID
RECEPTOR, BETA)		 3ihu TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 ALA A  58
LEU A  39
ILE A  78
ILE A  67
LEU A  44
 None
 0.85A 1xdkB-3ihuA:
undetectable		 1xdkB-3ihuA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_1
(RETINOIC ACID
RECEPTOR, BETA)		 3ihu TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 ALA A  58
LEU A  39
ILE A  78
ILE A  67
LEU A  44
 None
 0.85A 1xdkF-3ihuA:
undetectable		 1xdkF-3ihuA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)		 3ihu TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Cupriavidus
pinatubonensis) 		3 / 3 MET A 150
MET A  96
PHE A 143
 None
 1.28A 3gn8A-3ihuA:
undetectable		 3gn8A-3ihuA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KSZ_A_CYSA620_0
(LACTOPEROXIDASE)		 3ihu TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Cupriavidus
pinatubonensis) 		3 / 3 ARG A 186
GLU A 128
PHE A 136
 None
 0.95A 4kszA-3ihuA:
undetectable		 4kszA-3ihuA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN)		 3ihu TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 ALA A  58
GLY A  23
ALA A  46
GLY A  49
PHE A  48
 None
 1.07A 4r29A-3ihuA:
undetectable		 4r29A-3ihuA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN)		 3ihu TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Cupriavidus
pinatubonensis) 		5 / 12 ALA A  58
GLY A  23
ALA A  46
GLY A  49
PHE A  48
 None
 1.10A 4r29B-3ihuA:
undetectable		 4r29B-3ihuA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_B_BEZB306_0
(BETA-LACTAMASE VIM-2)		 3ihu TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY
(Cupriavidus
pinatubonensis) 		3 / 3 HIS A 207
ASN A 210
ALA A 214
 None
 0.13A 5n4tB-3ihuA:
undetectable		 5n4tB-3ihuA:
22.22