SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3iic'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 3iic CHEC DOMAIN PROTEIN
(Shewanella
loihica) 		4 / 8 ILE A 150
LEU A  10
PHE A 139
GLY A  28
 None
 1.07A 1os6A-3iicA:
undetectable		 1os6A-3iicA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 3iic CHEC DOMAIN PROTEIN
(Shewanella
loihica) 		5 / 12 GLY A  40
GLY A  44
THR A  93
VAL A  96
ILE A 148
 None
 0.96A 2wa2B-3iicA:
undetectable		 2wa2B-3iicA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3iic CHEC DOMAIN PROTEIN
(Shewanella
loihica) 		4 / 7 ALA A  38
ILE A 126
ILE A 136
HIS A 128
 None
 1.02A 2zm7A-3iicA:
undetectable		 2zm7A-3iicA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_2
(CYTOCHROME P450 2R1)		 3iic CHEC DOMAIN PROTEIN
(Shewanella
loihica) 		3 / 3 MET A  73
VAL A  85
GLU A  68
 None
 0.91A 3c6gA-3iicA:
undetectable		 3c6gA-3iicA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3iic CHEC DOMAIN PROTEIN
(Shewanella
loihica) 		5 / 12 MET A  95
VAL A  96
GLY A  98
ALA A 100
LEU A 104
 None
 1.11A 4rrwA-3iicA:
undetectable		 4rrwA-3iicA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3iic CHEC DOMAIN PROTEIN
(Shewanella
loihica) 		5 / 12 MET A  95
VAL A  96
GLY A  98
ALA A 100
LEU A 104
 None
 1.13A 4rrwB-3iicA:
undetectable		 4rrwB-3iicA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3iic CHEC DOMAIN PROTEIN
(Shewanella
loihica) 		5 / 12 MET A  95
VAL A  96
GLY A  98
ALA A 100
LEU A 104
 None
 1.11A 4rrzA-3iicA:
undetectable		 4rrzA-3iicA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3iic CHEC DOMAIN PROTEIN
(Shewanella
loihica) 		5 / 12 MET A  95
VAL A  96
GLY A  98
ALA A 100
LEU A 104
 None
 1.13A 4rrzB-3iicA:
undetectable		 4rrzB-3iicA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 3iic CHEC DOMAIN PROTEIN
(Shewanella
loihica) 		4 / 7 PHE A 111
ALA A 100
SER A  12
ILE A 148
 None
 0.93A 4uymA-3iicA:
undetectable		 4uymA-3iicA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3iic CHEC DOMAIN PROTEIN
(Shewanella
loihica) 		5 / 12 GLY A  90
LEU A  65
ILE A 142
TYR A 143
THR A  93
 None
 1.17A 5eskA-3iicA:
undetectable		 5eskA-3iicA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3iic CHEC DOMAIN PROTEIN
(Shewanella
loihica) 		5 / 12 MET A  95
VAL A  96
GLY A  98
ALA A 100
LEU A 104
 None
 0.95A 5iktA-3iicA:
undetectable		 5iktA-3iicA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 3iic CHEC DOMAIN PROTEIN
(Shewanella
loihica) 		5 / 12 GLY A  40
GLY A  44
THR A  93
VAL A  96
ILE A 148
 None
 0.95A 5m5bA-3iicA:
undetectable		 5m5bA-3iicA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_D_SAMD301_0
(NS5)		 3iic CHEC DOMAIN PROTEIN
(Shewanella
loihica) 		5 / 12 GLY A  40
GLY A  44
THR A  93
VAL A  96
ILE A 148
 None
 0.99A 5njvD-3iicA:
undetectable		 5njvD-3iicA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYO_A_LDPA901_0
(EBONY)		 3iic CHEC DOMAIN PROTEIN
(Shewanella
loihica) 		4 / 5 VAL A 118
LEU A  45
HIS A 128
THR A  93
 None
 1.37A 6dyoA-3iicA:
undetectable		 6dyoA-3iicA:
22.22