SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ijp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FPQ_A_SAMA1699_0
(ISOLIQUIRITIGENIN
2'-O-METHYLTRANSFERA
SE)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		5 / 10 LEU A  32
VAL A   6
ASP A  60
ALA A  88
ASN A  85
 None
 1.37A 1fpqA-3ijpA:
5.8		 1fpqA-3ijpA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		5 / 12 ALA A   8
VAL A  55
ASP A  43
GLY A  13
ILE A  17
 None
 1.00A 2dcfA-3ijpA:
undetectable		 2dcfA-3ijpA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		4 / 7 ILE A  48
LEU A  47
VAL A  31
THR A  18
 None
 0.80A 2wd9A-3ijpA:
3.1		 2wd9A-3ijpA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		4 / 8 THR A  98
GLN A  76
SER A  75
TYR A  83
 NAP  A 300 ( 4.4A)
NAP  A 300 (-4.9A)
NAP  A 300 (-4.7A)
None
 1.08A 2xz5A-3ijpA:
undetectable
2xz5C-3ijpA:
undetectable		 2xz5A-3ijpA:
21.59
2xz5C-3ijpA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A65_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		5 / 12 ALA A   8
VAL A  55
ASP A  43
GLY A  13
ILE A  17
 None
 1.08A 3a65A-3ijpA:
undetectable		 3a65A-3ijpA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		4 / 8 ARG A 177
PRO A 162
SER A 163
GLY A 202
 None
None
UNX  A 271 ( 4.9A)
None
 1.14A 3hcrA-3ijpA:
2.5		 3hcrA-3ijpA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		3 / 3 SER A 163
GLY A 164
THR A 165
 UNX  A 271 ( 4.9A)
UNX  A 271 ( 3.7A)
UNX  A 270 ( 4.5A)
 0.16A 3k9wA-3ijpA:
3.6		 3k9wA-3ijpA:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVC_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		4 / 6 HIS A 215
ARG A 207
HIS A 154
ASP A 160
 None
None
UNX  A 268 ( 4.4A)
NAP  A 300 (-3.6A)
 1.16A 3nvcA-3ijpA:
undetectable		 3nvcA-3ijpA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		4 / 6 THR A  98
GLN A  76
ILE A 109
SER A  75
 NAP  A 300 ( 4.4A)
NAP  A 300 (-4.9A)
None
NAP  A 300 (-4.7A)
 1.00A 3peoG-3ijpA:
undetectable		 3peoG-3ijpA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		4 / 5 GLY A  97
ILE A  96
VAL A   6
SER A  80
 NAP  A 300 (-3.5A)
None
None
None
 1.27A 4d33A-3ijpA:
undetectable		 4d33A-3ijpA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DCM_A_SAMA401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE G)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		5 / 11 ALA A  44
GLY A  10
GLY A   7
ILE A  17
ASN A 157
 None
NAP  A 300 (-3.3A)
NAP  A 300 (-3.3A)
None
None
 1.05A 4dcmA-3ijpA:
5.2		 4dcmA-3ijpA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_A_BEZA1000_0
(BENZOATE-COENZYME A
LIGASE)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		4 / 7 ALA A  64
ALA A   8
GLY A   7
ILE A  57
 None
None
NAP  A 300 (-3.3A)
None
 0.64A 4eatA-3ijpA:
2.4		 4eatA-3ijpA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		5 / 11 SER A 236
ILE A 237
LEU A 131
ASP A 214
GLY A 213
 None
None
None
None
UNX  A 268 ( 3.9A)
 1.04A 4fogA-3ijpA:
undetectable		 4fogA-3ijpA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		5 / 12 SER A 236
ILE A 237
LEU A 131
ASP A 214
GLY A 213
 None
None
None
None
UNX  A 268 ( 3.9A)
 0.98A 4foxA-3ijpA:
undetectable		 4foxA-3ijpA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		5 / 12 SER A 236
ILE A 237
LEU A 131
ASP A 214
GLY A 213
 None
None
None
None
UNX  A 268 ( 3.9A)
 0.99A 4foxB-3ijpA:
undetectable		 4foxB-3ijpA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_G_D16G301_1
(THYMIDYLATE SYNTHASE)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		5 / 12 SER A 236
ILE A 237
LEU A 131
ASP A 214
GLY A 213
 None
None
None
None
UNX  A 268 ( 3.9A)
 0.98A 4foxG-3ijpA:
undetectable		 4foxG-3ijpA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J5J_B_478B401_2
(PROTEASE)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		5 / 10 ASN A   9
ILE A  57
GLY A  49
VAL A  55
VAL A  31
 NAP  A 300 (-3.1A)
None
None
None
None
 1.03A 4j5jB-3ijpA:
undetectable		 4j5jB-3ijpA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT8_A_TMQA302_1
(RV2671)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		5 / 12 ILE A 217
GLY A 170
ALA A 173
ARG A 196
GLU A 149
 None
 1.31A 4xt8A-3ijpA:
undetectable		 4xt8A-3ijpA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		5 / 12 ILE A  20
LEU A  47
VAL A  31
GLY A  70
THR A  68
 None
 1.12A 5byjA-3ijpA:
undetectable		 5byjA-3ijpA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		4 / 6 GLU A 149
GLY A 202
ARG A 189
ARG A 177
 None
 1.37A 5jcnB-3ijpA:
4.3		 5jcnB-3ijpA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		3 / 3 ARG A 189
ILE A 150
PHE A 203
 None
 0.73A 5kirA-3ijpA:
undetectable		 5kirA-3ijpA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		5 / 12 GLY A  97
SER A  80
VAL A   5
THR A   4
ALA A 245
 NAP  A 300 (-3.5A)
None
None
None
None
 1.17A 5kpcB-3ijpA:
undetectable		 5kpcB-3ijpA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		5 / 10 ILE A 148
ILE A 217
LEU A 169
ILE A 179
ASN A 178
 None
 1.38A 5vkqA-3ijpA:
undetectable
5vkqD-3ijpA:
undetectable		 5vkqA-3ijpA:
11.53
5vkqD-3ijpA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		5 / 10 ILE A 179
ASN A 178
ILE A 148
ILE A 217
LEU A 169
 None
 1.36A 5vkqA-3ijpA:
undetectable
5vkqB-3ijpA:
undetectable		 5vkqA-3ijpA:
11.53
5vkqB-3ijpA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3ijp DIHYDRODIPICOLINATE
REDUCTASE
(Bartonella
henselae) 		5 / 10 ILE A 179
ASN A 178
ILE A 148
ILE A 217
LEU A 169
 None
 1.36A 5vkqC-3ijpA:
undetectable
5vkqD-3ijpA:
undetectable		 5vkqC-3ijpA:
11.53
5vkqD-3ijpA:
11.53