SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ijs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAV_A_RAVA183_1
(FERRITIN LIGHT CHAIN)		 3ijs IMMUNOGLOBULIN HEAVY
CHAIN (IGG3)
(Mus
musculus) 		4 / 6 LEU B  48
SER B  60
TYR B  59
ALA B  61
 None
 0.99A 3ravA-3ijsB:
undetectable		 3ravA-3ijsB:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3ijs IMMUNOGLOBULIN HEAVY
CHAIN (IGG3)
(Mus
musculus) 		4 / 5 TYR B  90
LEU B  80
LEU B  82
ARG B  66
 None
 1.25A 4em2A-3ijsB:
undetectable		 4em2A-3ijsB:
19.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 3ijs IMMUNOGLOBULIN HEAVY
CHAIN (IGG3)
(Mus
musculus) 		4 / 5 SER B 112
ALA B 114
PHE B 146
LEU B 170
 None
 0.26A 5mthA-3ijsB:
28.3		 5mthA-3ijsB:
57.46