SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ijt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 3ijt PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		3 / 3 LEU A  74
LEU A  83
SER A 103
 None
 0.64A 1tlmA-3ijtA:
undetectable		 1tlmA-3ijtA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)		 3ijt PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		3 / 3 ASP A 123
THR A  77
PRO A  78
 None
 0.66A 2q64B-3ijtA:
undetectable		 2q64B-3ijtA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 3ijt PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		4 / 7 SER A   0
LEU A  74
LEU A  83
SER A 103
 None
 0.93A 3cfqA-3ijtA:
undetectable
3cfqB-3ijtA:
undetectable		 3cfqA-3ijtA:
21.52
3cfqB-3ijtA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 3ijt PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		4 / 7 LEU A  74
LEU A  83
SER A 103
SER A   0
 None
 0.98A 4ikjA-3ijtA:
undetectable
4ikjB-3ijtA:
undetectable		 4ikjA-3ijtA:
21.95
4ikjB-3ijtA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 3ijt PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		4 / 7 SER A   0
LEU A  74
LEU A  83
SER A 103
 None
 0.96A 4ikkA-3ijtA:
undetectable
4ikkB-3ijtA:
undetectable		 4ikkA-3ijtA:
21.95
4ikkB-3ijtA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 3ijt PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		4 / 7 LEU A  74
LEU A  83
SER A 103
SER A   0
 None
 0.94A 4iklA-3ijtA:
undetectable
4iklB-3ijtA:
undetectable		 4iklA-3ijtA:
21.95
4iklB-3ijtA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 3ijt PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		4 / 8 SER A   0
LEU A  74
LEU A  83
SER A 103
 None
 0.94A 4iklA-3ijtA:
undetectable
4iklB-3ijtA:
undetectable		 4iklA-3ijtA:
21.95
4iklB-3ijtA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_F_MN9F401_0
(N-ACETYLNEURAMINATE
LYASE)		 3ijt PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		4 / 5 LEU A 104
ASP A 106
LEU A 117
THR A 110
 None
 1.28A 4wozF-3ijtA:
undetectable
4wozH-3ijtA:
undetectable		 4wozF-3ijtA:
20.61
4wozH-3ijtA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 3ijt PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		3 / 3 ASN A  91
SER A  97
ARG A  99
 None
 0.90A 5b2qA-3ijtA:
undetectable		 5b2qA-3ijtA:
7.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FZB_B_SRYB301_1
(STREPTOMYCIN
3''-ADENYLYLTRANSFER
ASE)		 3ijt PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		5 / 12 ASP A  73
TRP A  26
LEU A 135
ASP A  15
ILE A  88
 None
 1.34A 6fzbB-3ijtA:
undetectable		 6fzbB-3ijtA:
20.00