SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ik2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		3 / 3 TRP A 128
ALA A 118
VAL A 122
 None
 0.96A 1c4dA-3ik2A:
undetectable
1c4dB-3ik2A:
undetectable		 1c4dA-3ik2A:
4.27
1c4dB-3ik2A:
4.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ8_B_CAMB502_0
(CYTOCHROME P450-CAM)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		5 / 9 PHE A 155
TYR A  84
THR A 102
GLY A  44
VAL A 131
 None
 1.49A 1dz8B-3ik2A:
undetectable		 1dz8B-3ik2A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		4 / 8 ASP A 359
VAL A 395
GLY A 363
GLY A 364
 None
 0.91A 1ekjE-3ik2A:
undetectable
1ekjF-3ik2A:
undetectable		 1ekjE-3ik2A:
17.88
1ekjF-3ik2A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		5 / 10 LEU A 371
VAL A 395
TYR A 355
GLY A 364
TYR A 402
 None
 1.41A 1fk9A-3ik2A:
2.3		 1fk9A-3ik2A:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		5 / 10 LEU A 371
VAL A 395
TYR A 355
GLY A 364
TYR A 402
 None
 1.31A 1fkoA-3ik2A:
undetectable		 1fkoA-3ik2A:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JKH_A_EFZA999_1
(HIV-1 RT, A-CHAIN
HIV-1 RT, B-CHAIN)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		5 / 11 LEU A 371
VAL A 395
TYR A 355
GLY A 364
TYR A 402
 None
 1.36A 1jkhA-3ik2A:
2.0
1jkhB-3ik2A:
1.4		 1jkhA-3ik2A:
24.03
1jkhB-3ik2A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_C_LYAC315_1
(THYMIDYLATE SYNTHASE)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		5 / 10 ASP A 205
LEU A 177
GLY A 223
PHE A 222
ALA A 105
 None
 1.49A 1ju6C-3ik2A:
undetectable		 1ju6C-3ik2A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LW0_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		5 / 10 LEU A 371
VAL A 395
TYR A 355
GLY A 364
TYR A 402
 None
 1.39A 1lw0A-3ik2A:
undetectable		 1lw0A-3ik2A:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		5 / 11 LEU A 371
VAL A 395
TYR A 355
GLY A 364
TYR A 402
 None
 1.40A 1lwcA-3ik2A:
2.4		 1lwcA-3ik2A:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_B_DIFB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		5 / 9 VAL A 156
LEU A 159
LEU A 100
GLY A 174
ALA A 219
 None
 1.15A 1pxxB-3ik2A:
undetectable		 1pxxB-3ik2A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_D_DIFD3701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		5 / 10 VAL A 156
LEU A 159
LEU A 100
GLY A 174
ALA A 219
 None
 1.16A 1pxxD-3ik2A:
undetectable		 1pxxD-3ik2A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		4 / 6 ILE A 191
GLY A 106
ALA A 105
HIS A 188
 None
 0.91A 1wmqA-3ik2A:
undetectable		 1wmqA-3ik2A:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		4 / 6 ILE A 191
GLY A 106
ALA A 105
HIS A 188
 None
 0.93A 1wmqB-3ik2A:
undetectable		 1wmqB-3ik2A:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		4 / 6 ILE A 191
GLY A 106
ALA A 105
HIS A 188
 None
 0.92A 1wpuA-3ik2A:
undetectable		 1wpuA-3ik2A:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		4 / 6 ILE A 191
GLY A 106
ALA A 105
HIS A 188
 None
 0.91A 1wpuB-3ik2A:
undetectable		 1wpuB-3ik2A:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		4 / 6 ILE A 191
GLY A 106
ALA A 105
HIS A 188
 None
 0.92A 1wrqA-3ik2A:
undetectable		 1wrqA-3ik2A:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		4 / 6 ILE A 191
GLY A 106
ALA A 105
HIS A 188
 None
 0.92A 1wrqB-3ik2A:
undetectable		 1wrqB-3ik2A:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		3 / 3 THR A  85
PRO A  80
TYR A 158
 None
 0.78A 2dxrA-3ik2A:
undetectable		 2dxrA-3ik2A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_D_SALD5006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		4 / 5 ARG A  36
THR A 102
LEU A 177
ALA A 225
 None
 1.20A 2e1qD-3ik2A:
undetectable		 2e1qD-3ik2A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		4 / 6 TYR A 466
GLY A 438
ASP A 437
ASN A 439
 None
 1.18A 2g72A-3ik2A:
undetectable		 2g72A-3ik2A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HND_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		5 / 10 LEU A 371
VAL A 395
TYR A 355
GLY A 364
TYR A 402
 None
 1.41A 2hndA-3ik2A:
undetectable		 2hndA-3ik2A:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HNY_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		5 / 10 LEU A 371
VAL A 395
TYR A 355
GLY A 364
TYR A 402
 None
 1.41A 2hnyA-3ik2A:
1.8		 2hnyA-3ik2A:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		6 / 12 ASN A 179
GLU A 180
HIS A 277
TYR A 279
GLU A 352
TRP A 385
 None
 0.73A 2v3dA-3ik2A:
15.3		 2v3dA-3ik2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		5 / 11 ASN A 179
GLU A 180
TYR A 279
GLU A 352
TRP A 385
 None
 0.83A 2v3dB-3ik2A:
15.2		 2v3dB-3ik2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		4 / 8 ILE A  37
SER A 176
SER A 351
ASN A  24
 None
 0.92A 3lslA-3ik2A:
undetectable
3lslD-3ik2A:
undetectable		 3lslA-3ik2A:
18.55
3lslD-3ik2A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		4 / 8 ASN A  24
ILE A  37
SER A 176
SER A 351
 None
 0.92A 3lslA-3ik2A:
undetectable
3lslD-3ik2A:
undetectable		 3lslA-3ik2A:
18.55
3lslD-3ik2A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		5 / 12 LEU A 371
VAL A 395
TYR A 355
GLY A 364
TYR A 402
 None
 1.23A 3medA-3ik2A:
2.2
3medB-3ik2A:
2.4		 3medA-3ik2A:
24.19
3medB-3ik2A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QIP_A_NVPA561_1
(REVERSE HIV-1
REVERSE
TRANSCRIPTASE P66)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		5 / 10 LEU A 371
VAL A 395
TYR A 355
GLY A 364
TYR A 402
 None
 1.46A 3qipA-3ik2A:
2.3		 3qipA-3ik2A:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		3 / 3 GLY A  38
THR A 102
ASN A 179
 None
 0.72A 3v4tD-3ik2A:
0.2		 3v4tD-3ik2A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		4 / 6 ASP A 147
ASP A 112
ASN A  46
GLU A  48
 CA  A 514 (-3.0A)
GOL  A 528 (-4.4A)
None
CA  A 514 (-2.2A)
 1.25A 3vywA-3ik2A:
undetectable		 3vywA-3ik2A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		5 / 12 HIS A  88
GLY A 174
LEU A 159
TYR A 163
ALA A 273
 None
 1.22A 3vywD-3ik2A:
undetectable		 3vywD-3ik2A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_1
(MNMC2)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		4 / 5 ASP A 147
ASP A 112
ASN A  46
GLU A  48
 CA  A 514 (-3.0A)
GOL  A 528 (-4.4A)
None
CA  A 514 (-2.2A)
 1.26A 3vywD-3ik2A:
undetectable		 3vywD-3ik2A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		4 / 7 VAL A  32
PHE A  27
VAL A 395
ILE A  20
 None
 0.95A 3zjqA-3ik2A:
undetectable		 3zjqA-3ik2A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		3 / 3 PHE A  27
VAL A 395
GLU A 358
 None
 0.70A 4fvqA-3ik2A:
2.1		 4fvqA-3ik2A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_1
(MDR769 HIV-1
PROTEASE)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		5 / 11 ALA A 302
ASP A 298
ILE A 361
THR A 291
THR A 290
 None
 1.13A 4l1aA-3ik2A:
undetectable		 4l1aA-3ik2A:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		3 / 3 ASP A 253
TRP A 278
SER A 337
 None
None
GOL  A 517 (-2.6A)
 1.05A 4lrhA-3ik2A:
undetectable		 4lrhA-3ik2A:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJG_B_SAMB302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		5 / 12 THR A 415
ASN A  10
SER A 462
LYS A 464
ASP A 442
 None
GOL  A 516 (-3.8A)
GOL  A 516 (-3.2A)
GOL  A 516 (-4.9A)
None
 1.22A 4njgB-3ik2A:
1.7		 4njgB-3ik2A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP1_A_LDPA708_1
(DOPAMINE
TRANSPORTER, ISOFORM
B)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		5 / 10 PHE A 222
ALA A 219
VAL A 212
SER A 176
GLY A 174
 None
 1.39A 4xp1A-3ik2A:
undetectable		 4xp1A-3ik2A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP4_A_COCA706_1
(DOPAMINE TRANSPORTER)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		5 / 11 PHE A 381
ASP A 275
ALA A 225
TYR A 279
SER A 349
 None
 1.15A 4xp4A-3ik2A:
undetectable		 4xp4A-3ik2A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_B_ACTB401_0
(3C-LIKE PROTEINASE)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		3 / 3 ARG A  35
ASP A  26
TYR A  70
 GOL  A 515 (-4.6A)
GOL  A 515 (-4.0A)
GOL  A 515 (-4.2A)
 0.67A 4yo9B-3ik2A:
undetectable		 4yo9B-3ik2A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZGF_A_BEZA210_0
(UNCHARACTERIZED
PROTEIN)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		4 / 4 VAL A  32
ALA A  30
ASN A  29
GLN A 396
 None
None
GOL  A 522 (-2.8A)
None
 0.95A 4zgfA-3ik2A:
undetectable		 4zgfA-3ik2A:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		4 / 6 PHE A 474
SER A 362
HIS A 360
LEU A 502
 None
 1.47A 5dzka-3ik2A:
2.2
5dzko-3ik2A:
undetectable		 5dzka-3ik2A:
18.15
5dzko-3ik2A:
0.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		5 / 12 LEU A 100
ALA A  81
PHE A 155
LEU A 208
VAL A 212
 None
 1.14A 5tudA-3ik2A:
undetectable		 5tudA-3ik2A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		4 / 8 ALA A  15
SER A 432
THR A 434
GLY A 375
 None
 1.02A 5v0vA-3ik2A:
undetectable		 5v0vA-3ik2A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA503_1
(CYTOCHROME P450 2C9)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		4 / 5 PRO A 344
GLY A 345
THR A 346
LYS A 347
 None
 1.07A 5x23A-3ik2A:
undetectable		 5x23A-3ik2A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA502_1
(CYTOCHROME P450 2C9)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		4 / 6 PRO A 344
GLY A 345
THR A 346
LYS A 347
 None
 1.03A 5xxiA-3ik2A:
undetectable		 5xxiA-3ik2A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		5 / 12 ASP A 275
GLY A  22
ALA A  34
ASN A  24
ASN A  40
 None
 1.19A 6bqgA-3ik2A:
undetectable		 6bqgA-3ik2A:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		5 / 10 LEU A 371
VAL A 395
TYR A 355
GLY A 364
TYR A 402
 None
 1.41A 6bsgA-3ik2A:
undetectable		 6bsgA-3ik2A:
10.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3ik2 ENDOGLUCANASE A
(Clostridium
acetobutylicum) 		3 / 3 THR A 383
GLU A 358
ASN A  24
 None
 0.91A 6nj9K-3ik2A:
undetectable		 6nj9K-3ik2A:
19.68