SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ik5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0O_A_SAMA501_1 (PEPTIDE N-METHYLTRANSFERASE)	3ik5	PROTEIN NEF (Simian immunodeficiency virus)	3 / 3	ALA A 116 GLN A 157 THR A 170	ALA A 116 ( 0.0A) GLN A 157 ( 0.6A) THR A 170 ( 0.8A)	0.57A	5n0oA-3ik5A: undetectable	5n0oA-3ik5A: 17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_B_PCFB1806_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	3ik5	PROTEIN NEF (Simian immunodeficiency virus)	4 / 6	ILE A 153 ILE A 123 LEU A 142 PHE A 215	ILE A 153 ( 0.7A) ILE A 123 ( 0.7A) LEU A 142 ( 0.6A) PHE A 215 ( 1.3A)	0.88A	5vkqB-3ik5A: undetectable 5vkqC-3ik5A: undetectable	5vkqB-3ik5A: 6.00 5vkqC-3ik5A: 6.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_C_PCFC1807_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	3ik5	PROTEIN NEF (Simian immunodeficiency virus)	4 / 6	ILE A 153 ILE A 123 LEU A 142 PHE A 215	ILE A 153 ( 0.7A) ILE A 123 ( 0.7A) LEU A 142 ( 0.6A) PHE A 215 ( 1.3A)	0.90A	5vkqC-3ik5A: undetectable 5vkqD-3ik5A: undetectable	5vkqC-3ik5A: 6.00 5vkqD-3ik5A: 6.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AN0_A_HISA520_0 (HISTIDINOL DEHYDROGENASE)	3ik5	PROTEIN NEF (Simian immunodeficiency virus)	4 / 6	GLU A 150 LYS A 148 ARG A 109 GLU A 147	GLU A 150 ( 0.6A) LYS A 148 ( 0.0A) ARG A 109 ( 0.6A) GLU A 147 ( 0.6A)	1.06A	6an0A-3ik5A: undetectable	6an0A-3ik5A: 14.25

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5N0O_A_SAMA501_1","PEPTIDE N-METHYLTRANSFERASE","3ik5","PROTEIN NEF","Simian immunodeficiency virus",3,"ALA A 116;GLN A 157;THR A 170","ALA A 116 ( 0.0A);GLN A 157 ( 0.6A);THR A 170 ( 0.8A)","0.57A","5n0oA-3ik5A:undetectable","5n0oA-3ik5A:17.97"],["5VKQ_B_PCFB1806_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","3ik5","PROTEIN NEF","Simian immunodeficiency virus",4,"ILE A 153;ILE A 123;LEU A 142;PHE A 215","ILE A 153 ( 0.7A);ILE A 123 ( 0.7A);LEU A 142 ( 0.6A);PHE A 215 ( 1.3A)","0.88A","5vkqB-3ik5A:undetectable;5vkqC-3ik5A:undetectable","5vkqB-3ik5A:6.00;5vkqC-3ik5A:6.00"],["5VKQ_C_PCFC1807_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","3ik5","PROTEIN NEF","Simian immunodeficiency virus",4,"ILE A 153;ILE A 123;LEU A 142;PHE A 215","ILE A 153 ( 0.7A);ILE A 123 ( 0.7A);LEU A 142 ( 0.6A);PHE A 215 ( 1.3A)","0.90A","5vkqC-3ik5A:undetectable;5vkqD-3ik5A:undetectable","5vkqC-3ik5A:6.00;5vkqD-3ik5A:6.00"],["6AN0_A_HISA520_0","HISTIDINOL DEHYDROGENASE","3ik5","PROTEIN NEF","Simian immunodeficiency virus",4,"GLU A 150;LYS A 148;ARG A 109;GLU A 147","GLU A 150 ( 0.6A);LYS A 148 ( 0.0A);ARG A 109 ( 0.6A);GLU A 147 ( 0.6A)","1.06A","6an0A-3ik5A:undetectable","6an0A-3ik5A:14.25"]]