SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ikb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 3ikb UNCHARACTERIZED
CONSERVED PROTEIN
(Streptococcus
mutans) 		3 / 3 ASN A  38
PHE A  74
VAL A  82
 None
 0.85A 1kijA-3ikbA:
undetectable		 1kijA-3ikbA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)		 3ikb UNCHARACTERIZED
CONSERVED PROTEIN
(Streptococcus
mutans) 		4 / 8 MET A 170
LEU A 142
VAL A 160
VAL A 180
 None
 0.98A 2bdmA-3ikbA:
undetectable		 2bdmA-3ikbA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_C_TOPC1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3ikb UNCHARACTERIZED
CONSERVED PROTEIN
(Streptococcus
mutans) 		5 / 10 ILE A  83
ILE A 112
ILE A  11
PHE A  87
TYR A  54
 None
None
None
None
FLC  A 196 (-4.2A)
 1.15A 2w9sC-3ikbA:
undetectable		 2w9sC-3ikbA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 3ikb UNCHARACTERIZED
CONSERVED PROTEIN
(Streptococcus
mutans) 		5 / 12 ILE A 123
VAL A 180
VAL A 181
LEU A 121
LEU A 153
 None
 1.26A 5tiwA-3ikbA:
undetectable		 5tiwA-3ikbA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 3ikb UNCHARACTERIZED
CONSERVED PROTEIN
(Streptococcus
mutans) 		5 / 12 ILE A  11
PHE A 104
ASN A  17
PHE A  20
ILE A 112
 None
 1.02A 6dwnB-3ikbA:
undetectable		 6dwnB-3ikbA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 3ikb UNCHARACTERIZED
CONSERVED PROTEIN
(Streptococcus
mutans) 		5 / 12 ILE A  11
PHE A 104
ASN A  17
PHE A  20
ILE A 112
 None
 1.04A 6dwnC-3ikbA:
undetectable		 6dwnC-3ikbA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_C_SAMC301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 3ikb UNCHARACTERIZED
CONSERVED PROTEIN
(Streptococcus
mutans) 		5 / 12 LEU A 121
ILE A 191
ILE A 123
VAL A  40
ILE A  37
 None
 1.01A 6emuC-3ikbA:
undetectable		 6emuC-3ikbA:
18.36