SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ikc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3ikc IMMUNOGLOBULIN LIGHT
CHAIN (IGG3)
(Mus
musculus) 		4 / 5 LEU A 178
GLY A 127
PRO A 119
VAL A 131
 None
 0.92A 2aojA-3ikcA:
undetectable		 2aojA-3ikcA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ikc IMMUNOGLOBULIN LIGHT
CHAIN (IGG3)
(Mus
musculus) 		4 / 8 ASP A 166
THR A 171
TYR A 172
LEU A  83
 None
 1.15A 3ablA-3ikcA:
undetectable
3ablC-3ikcA:
undetectable
3ablP-3ikcA:
undetectable		 3ablA-3ikcA:
16.53
3ablC-3ikcA:
20.00
3ablP-3ikcA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ikc IMMUNOGLOBULIN LIGHT
CHAIN (IGG3)
(Mus
musculus) 		4 / 8 ASP A 166
THR A 171
TYR A 172
LEU A  83
 None
 1.15A 3abmA-3ikcA:
undetectable
3abmC-3ikcA:
undetectable
3abmP-3ikcA:
undetectable		 3abmA-3ikcA:
16.53
3abmC-3ikcA:
20.00
3abmP-3ikcA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ikc IMMUNOGLOBULIN LIGHT
CHAIN (IGG3)
(Mus
musculus) 		4 / 8 ASP A 166
THR A 171
TYR A 172
LEU A  83
 None
 1.14A 3x2qA-3ikcA:
undetectable
3x2qC-3ikcA:
undetectable
3x2qP-3ikcA:
undetectable		 3x2qA-3ikcA:
16.53
3x2qC-3ikcA:
20.00
3x2qP-3ikcA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ikc IMMUNOGLOBULIN LIGHT
CHAIN (IGG3)
(Mus
musculus) 		4 / 7 LEU A  83
ASP A 166
THR A 171
TYR A 172
 None
 1.15A 5wauC-3ikcA:
undetectable
5waua-3ikcA:
undetectable
5wauc-3ikcA:
undetectable		 5wauC-3ikcA:
20.00
5waua-3ikcA:
16.53
5wauc-3ikcA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ikc IMMUNOGLOBULIN LIGHT
CHAIN (IGG3)
(Mus
musculus) 		4 / 7 LEU A  83
ASP A 166
THR A 171
TYR A 172
 None
 1.18A 5z85C-3ikcA:
undetectable
5z85N-3ikcA:
undetectable
5z85P-3ikcA:
undetectable		 5z85C-3ikcA:
20.00
5z85N-3ikcA:
16.53
5z85P-3ikcA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ikc IMMUNOGLOBULIN LIGHT
CHAIN (IGG3)
(Mus
musculus) 		4 / 8 LEU A  83
ASP A 166
THR A 171
TYR A 172
 None
 1.19A 5zcoC-3ikcA:
undetectable
5zcoN-3ikcA:
undetectable
5zcoP-3ikcA:
undetectable		 5zcoC-3ikcA:
20.00
5zcoN-3ikcA:
16.53
5zcoP-3ikcA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ikc IMMUNOGLOBULIN LIGHT
CHAIN (IGG3)
(Mus
musculus) 		4 / 8 LEU A  83
ASP A 166
THR A 171
TYR A 172
 None
 1.21A 5zcpC-3ikcA:
undetectable
5zcpN-3ikcA:
undetectable
5zcpP-3ikcA:
undetectable		 5zcpC-3ikcA:
20.00
5zcpN-3ikcA:
16.53
5zcpP-3ikcA:
20.00