SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3il0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 3il0 AMINOPEPTIDASE P
XAA-PRO
AMINOPEPTIDASE
(Streptococcus
thermophilus) 		5 / 12 LEU A  88
ALA A  19
ASP A  86
ILE A  70
LEU A  51
 None
 1.00A 1tw4A-3il0A:
undetectable		 1tw4A-3il0A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 3il0 XAA-PRO
AMINOPEPTIDASE
AMINOPEPTIDASE P
(Streptococcus
thermophilus) 		5 / 11 LEU A 105
ALA A  19
LEU A  17
SER A 115
LEU A 114
 None
 0.87A 2c12F-3il0A:
undetectable		 2c12F-3il0A:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 3il0 XAA-PRO
AMINOPEPTIDASE
AMINOPEPTIDASE P
(Streptococcus
thermophilus) 		4 / 8 VAL A  22
VAL A  41
LEU A  31
THR A  32
 None
 0.89A 2gehA-3il0A:
undetectable		 2gehA-3il0A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3il0 XAA-PRO
AMINOPEPTIDASE
AMINOPEPTIDASE P
(Streptococcus
thermophilus) 		5 / 12 LEU A  88
ALA A  19
ASP A  86
ILE A  70
LEU A  51
 None
 0.83A 2jn3A-3il0A:
undetectable		 2jn3A-3il0A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3il0 XAA-PRO
AMINOPEPTIDASE
AMINOPEPTIDASE P
(Streptococcus
thermophilus) 		4 / 8 MET A 121
PHE A 120
ALA A  19
LEU A  17
 None
 1.02A 2o01A-3il0A:
undetectable		 2o01A-3il0A:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		 3il0 XAA-PRO
AMINOPEPTIDASE
AMINOPEPTIDASE P
(Streptococcus
thermophilus) 		4 / 6 ARG A   7
GLU A 123
PHE A 120
GLN A  14
 None
 1.34A 3gclA-3il0A:
undetectable		 3gclA-3il0A:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 3il0 XAA-PRO
AMINOPEPTIDASE
AMINOPEPTIDASE P
(Streptococcus
thermophilus) 		4 / 8 GLY A  92
MET A 121
PHE A   8
ILE A  43
 None
 0.92A 4j4vC-3il0A:
undetectable		 4j4vC-3il0A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3il0 AMINOPEPTIDASE P
XAA-PRO
AMINOPEPTIDASE
(Streptococcus
thermophilus) 		4 / 8 ALA A  19
ASP A  78
ILE A  79
ILE A 108
 None
 0.91A 4kttB-3il0A:
undetectable		 4kttB-3il0A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3il0 AMINOPEPTIDASE P
XAA-PRO
AMINOPEPTIDASE
(Streptococcus
thermophilus) 		4 / 8 ALA A  19
ASP A  78
ILE A  79
ILE A 108
 None
 0.87A 4ndnB-3il0A:
undetectable		 4ndnB-3il0A:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_2
(RIFAMPIN
MONOOXYGENASE)		 3il0 XAA-PRO
AMINOPEPTIDASE
AMINOPEPTIDASE P
(Streptococcus
thermophilus) 		4 / 6 GLN A 117
VAL A  97
LEU A  12
ARG A  48
 None
None
None
GOL  A 129 (-3.7A)
 1.26A 6brdB-3il0A:
undetectable		 6brdB-3il0A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3il0 AMINOPEPTIDASE P
XAA-PRO
AMINOPEPTIDASE
(Streptococcus
thermophilus) 		4 / 7 ALA A  19
ASP A  78
ILE A  79
ILE A 108
 None
 0.94A 6fbnA-3il0A:
undetectable		 6fbnA-3il0A:
17.43