SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3il3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_0
(MODIFICATION
METHYLASE RSRI)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		5 / 12 GLY A   9
SER A  10
VAL A 281
ALA A  66
ALA A  65
 None
 1.24A 1nw5A-3il3A:
undetectable		 1nw5A-3il3A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		5 / 12 VAL A  78
ASP A 107
SER A  84
GLY A 158
ILE A  44
 None
 1.33A 1xvaA-3il3A:
undetectable		 1xvaA-3il3A:
27.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		5 / 10 ILE A 137
ALA A  91
GLN A  93
ALA A  52
ILE A 165
 None
 0.95A 2aclC-3il3A:
undetectable		 2aclC-3il3A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		5 / 11 ALA A  79
SER A 311
GLY A 310
ALA A 302
SER A 120
 None
None
None
SCY  A 112 ( 3.8A)
None
 1.06A 2f162-3il3A:
undetectable		 2f162-3il3A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		5 / 11 ALA A  79
SER A 311
GLY A 310
ALA A 302
SER A 120
 None
None
None
SCY  A 112 ( 3.8A)
None
 1.06A 2f16N-3il3A:
undetectable		 2f16N-3il3A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		5 / 12 TYR A 117
ILE A 137
GLY A 114
GLY A 138
THR A 308
 None
None
SCY  A 112 ( 4.4A)
None
None
 1.11A 2okcA-3il3A:
undetectable		 2okcA-3il3A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		4 / 7 ALA A 254
THR A 253
ALA A 252
PRO A 242
 None
 0.80A 2ql8A-3il3A:
undetectable
2ql8B-3il3A:
undetectable		 2ql8A-3il3A:
19.42
2ql8B-3il3A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_B_DAHB2_1
(RANASMURFIN)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		4 / 8 ALA A  79
SER A 139
GLY A  55
ALA A  90
 None
 0.89A 2vh3B-3il3A:
undetectable		 2vh3B-3il3A:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_B_H4BB1902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		4 / 7 GLU A  31
ARG A 248
ILE A  33
TRP A  32
 None
 1.46A 3e7gA-3il3A:
undetectable
3e7gB-3il3A:
undetectable		 3e7gA-3il3A:
23.02
3e7gB-3il3A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		5 / 12 ALA A  79
SER A 311
GLY A 310
ALA A 302
SER A 120
 None
None
None
SCY  A 112 ( 3.8A)
None
 1.11A 3mg02-3il3A:
undetectable
3mg0V-3il3A:
undetectable		 3mg02-3il3A:
22.12
3mg0V-3il3A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		5 / 11 ALA A  79
SER A 311
GLY A 310
ALA A 302
SER A 120
 None
None
None
SCY  A 112 ( 3.8A)
None
 1.11A 3mg0N-3il3A:
undetectable		 3mg0N-3il3A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		4 / 7 ILE A 249
VAL A 216
LEU A 219
SER A 220
 None
 0.70A 3r9vA-3il3A:
undetectable
3r9vB-3il3A:
undetectable		 3r9vA-3il3A:
22.51
3r9vB-3il3A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		4 / 6 GLU A 301
GLY A 310
LEU A 299
GLU A 225
 None
 1.07A 3w9tB-3il3A:
undetectable		 3w9tB-3il3A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		4 / 6 GLU A 301
GLY A 310
LEU A 299
GLU A 225
 None
 1.07A 3w9tE-3il3A:
undetectable		 3w9tE-3il3A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		4 / 6 GLU A 301
GLY A 310
LEU A 299
GLU A 225
 None
 1.06A 3w9tF-3il3A:
undetectable		 3w9tF-3il3A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		4 / 7 LEU A   6
ALA A  62
VAL A  94
ILE A 165
 None
 0.95A 3wsjB-3il3A:
undetectable		 3wsjB-3il3A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_A_NCAA1536_0
(DIPHTHERIA TOXIN)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		4 / 6 GLY A   9
TYR A  11
ALA A  62
GLU A  57
 None
 0.92A 4ae1A-3il3A:
undetectable		 4ae1A-3il3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_0
(WBDD)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		5 / 12 ALA A  58
ILE A 165
ASN A  61
ILE A  73
ILE A 100
 None
 0.93A 4ax8A-3il3A:
2.0		 4ax8A-3il3A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_0
(WBDD)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		5 / 12 ALA A  58
ILE A 165
ASN A  61
ILE A  73
ILE A 100
 None
 0.93A 4azvA-3il3A:
undetectable		 4azvA-3il3A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDC_A_ASDA404_1
(3-KETOSTEROID
9ALPHA-HYDROXYLASE
OXYGENASE)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		5 / 12 LEU A 146
SER A 143
ALA A  45
MET A  54
ASP A 159
 None
 1.41A 4qdcA-3il3A:
undetectable		 4qdcA-3il3A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_1
(GLUCOCORTICOID
RECEPTOR)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		5 / 12 LEU A 247
ASN A 246
GLN A 244
MET A 261
PHE A 212
 None
 1.21A 4udcA-3il3A:
undetectable		 4udcA-3il3A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		5 / 12 HIS A 243
ALA A 245
GLY A 305
GLY A 310
LEU A 219
 SCY  A 112 ( 3.8A)
None
SCY  A 112 ( 4.1A)
None
None
 0.98A 4uilH-3il3A:
undetectable
4uilL-3il3A:
undetectable		 4uilH-3il3A:
19.64
4uilL-3il3A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		5 / 12 ASP A 150
SER A 152
VAL A 190
LEU A 189
GLY A 208
 None
 1.06A 4y8wA-3il3A:
undetectable		 4y8wA-3il3A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H4D_A_BBIA403_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		4 / 6 ARG A 217
GLU A 218
GLU A 224
VAL A 223
 None
 1.17A 5h4dA-3il3A:
undetectable		 5h4dA-3il3A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		5 / 12 VAL A 116
LEU A 227
LEU A 313
LEU A 237
PRO A 242
 None
 1.13A 5hnwB-3il3A:
undetectable		 5hnwB-3il3A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		5 / 12 VAL A 116
LEU A 227
LEU A 313
LEU A 237
PRO A 242
 None
 1.19A 5hnyB-3il3A:
undetectable		 5hnyB-3il3A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_1
(PROTEASE PR5-SQV)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		5 / 9 ALA A 122
ASP A 123
ILE A 174
ILE A 165
PRO A 280
 None
 1.05A 5kr2A-3il3A:
undetectable		 5kr2A-3il3A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_1
(PROTEASE PR5-SQV)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		5 / 9 ALA A 122
ASP A 123
ILE A 174
ILE A 165
PRO A 280
 None
 1.03A 5kr2C-3il3A:
undetectable		 5kr2C-3il3A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA510_1
(PROTON-GATED ION
CHANNEL)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		5 / 9 ILE A 165
ALA A 134
ILE A  73
ILE A 137
ALA A  59
 None
 1.12A 5mvmA-3il3A:
undetectable
5mvmE-3il3A:
undetectable		 5mvmA-3il3A:
15.86
5mvmE-3il3A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		4 / 8 VAL A  78
GLN A  95
GLY A  96
LEU A  97
 None
 0.85A 5w3jB-3il3A:
undetectable		 5w3jB-3il3A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		5 / 12 ILE A 137
ALA A  91
GLN A  93
ALA A  52
ILE A 165
 None
 1.00A 6a60D-3il3A:
undetectable		 6a60D-3il3A:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_B_GLYB709_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		4 / 5 GLY A 158
ASN A 274
ASP A 159
ARG A  42
 None
 1.39A 6dwdB-3il3A:
undetectable
6dwdD-3il3A:
undetectable		 6dwdB-3il3A:
20.50
6dwdD-3il3A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWJ_B_GLYB710_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3il3 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3
(Haemophilus
influenzae) 		4 / 5 ARG A  42
GLY A 158
ASN A 274
ASP A 159
 None
 1.38A 6dwjB-3il3A:
undetectable
6dwjD-3il3A:
undetectable		 6dwjB-3il3A:
20.50
6dwjD-3il3A:
20.50