SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ila'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 3ila RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 6 PHE A 133
ALA A 132
LEU A 131
SER A 124
 None
 0.94A 1sbrA-3ilaA:
undetectable
1sbrB-3ilaA:
undetectable		 1sbrA-3ilaA:
19.64
1sbrB-3ilaA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA602_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3ila RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 8 ILE A 107
LEU A 169
ILE A 170
HIS A 151
 None
 0.74A 2azxA-3ilaA:
undetectable		 2azxA-3ilaA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 3ila RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		3 / 3 SER A 119
HIS A 113
ASP A  61
 None
 0.78A 2wa2B-3ilaA:
undetectable		 2wa2B-3ilaA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_C_IPHC101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 3ila RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 6 CYH A  47
LEU A  37
HIS A 181
LEU A 180
 None
 0.94A 5hpuC-3ilaA:
undetectable
5hpuD-3ilaA:
undetectable		 5hpuC-3ilaA:
8.81
5hpuD-3ilaA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ila RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		4 / 5 TYR A 103
MET A 150
THR A 149
LEU A 171
 None
 1.44A 5x1bJ-3ilaA:
undetectable		 5x1bJ-3ilaA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3ila RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		5 / 12 SER A 183
THR A 184
LEU A 171
LEU A 118
VAL A 135
 None
 1.31A 6a93B-3ilaA:
undetectable		 6a93B-3ilaA:
17.38