SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ile'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB504_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3ile PUTATIVE
UNCHARACTERIZED
PROTEIN
(Acidianus
filamentous
virus
1) 		4 / 7 ILE A  92
PHE A  71
ALA A  69
ILE A 116
 None
 0.82A 1oniB-3ileA:
undetectable
1oniC-3ileA:
undetectable		 1oniB-3ileA:
21.12
1oniC-3ileA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3ile PUTATIVE
UNCHARACTERIZED
PROTEIN
(Acidianus
filamentous
virus
1) 		4 / 7 TYR A 133
MET A 142
ILE A 135
SER A 131
 None
 1.20A 2xytI-3ileA:
undetectable		 2xytI-3ileA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 3ile PUTATIVE
UNCHARACTERIZED
PROTEIN
(Acidianus
filamentous
virus
1) 		4 / 8 ILE A 102
LEU A 112
PHE A  71
GLY A  59
 None
 0.95A 3selX-3ileA:
undetectable		 3selX-3ileA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 3ile PUTATIVE
UNCHARACTERIZED
PROTEIN
(Acidianus
filamentous
virus
1) 		4 / 6 ILE A 102
LEU A 112
PHE A  71
GLY A  59
 None
 0.97A 3sj1X-3ileA:
undetectable		 3sj1X-3ileA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3ile PUTATIVE
UNCHARACTERIZED
PROTEIN
(Acidianus
filamentous
virus
1) 		6 / 12 ILE A  73
LEU A  60
PHE A  71
ILE A 102
LEU A 150
ILE A 146
 None
 1.49A 4i13A-3ileA:
undetectable		 4i13A-3ileA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 3ile PUTATIVE
UNCHARACTERIZED
PROTEIN
(Acidianus
filamentous
virus
1) 		4 / 4 HIS A  22
VAL A 128
LEU A  24
ALA A 126
 None
 1.35A 6d8pB-3ileA:
undetectable		 6d8pB-3ileA:
12.29