SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ilh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4001_1
(SERUM ALBUMIN)		 3ilh TWO COMPONENT
RESPONSE REGULATOR
(Cytophaga
hutchinsonii) 		4 / 5 ARG A 103
LYS A 107
ALA A 106
ASP A 101
 None
 1.18A 1e7bA-3ilhA:
undetectable		 1e7bA-3ilhA:
12.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FPQ_A_SAMA1699_0
(ISOLIQUIRITIGENIN
2'-O-METHYLTRANSFERA
SE)		 3ilh TWO COMPONENT
RESPONSE REGULATOR
(Cytophaga
hutchinsonii) 		5 / 10 ASN A 129
LEU A  12
VAL A  10
ASP A  14
ALA A 124
 None
 1.47A 1fpqA-3ilhA:
2.9		 1fpqA-3ilhA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_1
(TRANSTHYRETIN)		 3ilh TWO COMPONENT
RESPONSE REGULATOR
(Cytophaga
hutchinsonii) 		4 / 6 LYS A  48
LEU A  11
GLU A  51
ALA A  45
 None
 1.06A 1sn5A-3ilhA:
undetectable		 1sn5A-3ilhA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3ilh TWO COMPONENT
RESPONSE REGULATOR
(Cytophaga
hutchinsonii) 		5 / 12 ILE A  27
THR A  30
VAL A  33
ILE A   7
ASN A 129
 None
 1.12A 3kpdB-3ilhA:
undetectable		 3kpdB-3ilhA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		 3ilh TWO COMPONENT
RESPONSE REGULATOR
(Cytophaga
hutchinsonii) 		5 / 11 THR A  25
LEU A 122
VAL A  10
ILE A  36
SER A  38
 None
 1.42A 4lhmA-3ilhA:
undetectable		 4lhmA-3ilhA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_A_IPHA101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 3ilh TWO COMPONENT
RESPONSE REGULATOR
(Cytophaga
hutchinsonii) 		4 / 4 CYH A  63
LEU A 130
LEU A 122
ALA A 126
 None
 0.86A 5hpuA-3ilhA:
undetectable
5hpuB-3ilhA:
undetectable		 5hpuA-3ilhA:
10.45
5hpuB-3ilhA:
8.82