SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3iln'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3iln LAMINARINASE
(Rhodothermus
marinus) 		4 / 4 GLY A 231
GLY A 105
GLY A 235
GLY A 227
 None
 0.66A 3bogD-3ilnA:
undetectable		 3bogD-3ilnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 3iln LAMINARINASE
(Rhodothermus
marinus) 		4 / 7 TRP A 107
GLU A 134
ASP A 131
THR A 229
 GOL  A 300 (-3.4A)
GOL  A 300 (-3.5A)
GOL  A 300 (-3.6A)
None
 1.36A 3dzgB-3ilnA:
undetectable		 3dzgB-3ilnA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3iln LAMINARINASE
(Rhodothermus
marinus) 		4 / 4 PRO A  25
LEU A  24
ILE A  52
ARG A  51
 None
 1.38A 3w1wA-3ilnA:
undetectable		 3w1wA-3ilnA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_A_LURA201_1
(TRANSTHYRETIN)		 3iln LAMINARINASE
(Rhodothermus
marinus) 		3 / 3 LYS A 150
LEU A 156
ALA A 151
 None
 0.84A 4iizA-3ilnA:
undetectable		 4iizA-3ilnA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3iln LAMINARINASE
(Rhodothermus
marinus) 		4 / 5 TYR A 253
ARG A 251
ASP A 248
VAL A 143
 None
None
CA  A 400 (-3.4A)
None
 1.49A 4nkvB-3ilnA:
undetectable		 4nkvB-3ilnA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3iln LAMINARINASE
(Rhodothermus
marinus) 		4 / 5 TYR A 253
ARG A 251
ASP A 248
VAL A 166
 None
None
CA  A 400 (-3.4A)
None
 1.35A 4nkvB-3ilnA:
undetectable		 4nkvB-3ilnA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 3iln LAMINARINASE
(Rhodothermus
marinus) 		3 / 3 GLU A  18
TYR A 253
GLU A  95
 None
 0.78A 4ryaA-3ilnA:
undetectable		 4ryaA-3ilnA:
21.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XDQ_A_BEZA306_0
(GLYCOSIDE HYDROLASE
FAMILY PROTEIN)		 3iln LAMINARINASE
(Rhodothermus
marinus) 		3 / 3 ARG A 210
ASP A 208
TRP A 209
 None
 1.07A 4xdqA-3ilnA:
24.5		 4xdqA-3ilnA:
30.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CU6_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3iln LAMINARINASE
(Rhodothermus
marinus) 		4 / 6 ILE A 110
VAL A 143
PRO A 108
ALA A 133
 None
 0.92A 5cu6A-3ilnA:
undetectable		 5cu6A-3ilnA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 3iln LAMINARINASE
(Rhodothermus
marinus) 		5 / 12 ALA A  66
SER A  78
PHE A 241
GLN A 234
GLY A 228
 None
 1.18A 5m54E-3ilnA:
undetectable		 5m54E-3ilnA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3iln LAMINARINASE
(Rhodothermus
marinus) 		4 / 8 TRP A 230
TRP A 107
THR A 146
GLN A 159
 None
GOL  A 300 (-3.4A)
None
None
 1.41A 5tzoC-3ilnA:
5.3		 5tzoC-3ilnA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3iln LAMINARINASE
(Rhodothermus
marinus) 		3 / 3 GLY A  92
TRP A  89
VAL A  14
 None
 0.77A 5vuoB-3ilnA:
undetectable		 5vuoB-3ilnA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3iln LAMINARINASE
(Rhodothermus
marinus) 		5 / 9 VAL A 250
VAL A 252
ILE A 178
MET A 112
ILE A 132
 None
 1.16A 5yf9X-3ilnA:
undetectable		 5yf9X-3ilnA:
17.13