SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ilr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)		 3ilr HEPARIN LYASE I
(Bacteroides
thetaiotaomicron) 		4 / 7 ASP A 254
SER A 276
SER A 244
ASN A 243
 None
None
None
SGN  A 377 (-3.5A)
 1.23A 1ig3A-3ilrA:
undetectable
1ig3B-3ilrA:
undetectable		 1ig3A-3ilrA:
20.26
1ig3B-3ilrA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 3ilr HEPARIN LYASE I
(Bacteroides
thetaiotaomicron) 		4 / 6 TYR A 280
VAL A 133
ILE A 135
LEU A 237
 None
 1.25A 1j96A-3ilrA:
undetectable		 1j96A-3ilrA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_A_FK5A301_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 3ilr HEPARIN LYASE I
(Bacteroides
thetaiotaomicron) 		5 / 9 LEU A 229
VAL A 335
ILE A 334
ILE A 293
PHE A 238
 None
 0.73A 1q6iA-3ilrA:
undetectable		 1q6iA-3ilrA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3ilr HEPARIN LYASE I
(Bacteroides
thetaiotaomicron) 		5 / 11 TYR A  90
ILE A  31
VAL A  37
ALA A  38
ILE A  47
 None
 1.28A 1uduA-3ilrA:
undetectable		 1uduA-3ilrA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3ilr HEPARIN LYASE I
(Bacteroides
thetaiotaomicron) 		4 / 5 PHE A 147
PHE A 233
PHE A 284
VAL A 133
 None
 1.22A 2lh6A-3ilrA:
undetectable		 2lh6A-3ilrA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3ilr HEPARIN LYASE I
(Bacteroides
thetaiotaomicron) 		4 / 6 ILE A 240
ILE A 135
TYR A 368
LEU A 229
 None
 1.12A 3adsA-3ilrA:
undetectable		 3adsA-3ilrA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 3ilr HEPARIN LYASE I
(Bacteroides
thetaiotaomicron) 		4 / 6 PHE A 174
PHE A 183
THR A 157
VAL A 159
 None
 1.09A 3lb3A-3ilrA:
undetectable		 3lb3A-3ilrA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 3ilr HEPARIN LYASE I
(Bacteroides
thetaiotaomicron) 		4 / 6 PHE A 174
PHE A 183
THR A 157
VAL A 159
 None
 1.10A 3lb3B-3ilrA:
undetectable		 3lb3B-3ilrA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6D_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3ilr HEPARIN LYASE I
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 301
VAL A 297
TRP A 150
PRO A 227
 None
None
None
SGN  A 377 (-4.2A)
 1.20A 3n6dA-3ilrA:
undetectable
3n6dB-3ilrA:
undetectable		 3n6dA-3ilrA:
23.58
3n6dB-3ilrA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA271_0
(PROTEIN SSM1)		 3ilr HEPARIN LYASE I
(Bacteroides
thetaiotaomicron) 		4 / 5 GLY A 224
GLU A 222
GLY A 225
PRO A 154
 IXD  A 379 (-3.0A)
CA  A   1 (-2.2A)
SGN  A 377 ( 2.9A)
None
 0.96A 3onnA-3ilrA:
undetectable		 3onnA-3ilrA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R6W_A_NFZA213_1
(FMN-DEPENDENT
NADH-AZOREDUCTASE 1)		 3ilr HEPARIN LYASE I
(Bacteroides
thetaiotaomicron) 		5 / 10 PHE A 352
GLY A 355
PHE A 238
PHE A 295
PHE A 131
 None
 1.49A 3r6wA-3ilrA:
undetectable
3r6wB-3ilrA:
undetectable		 3r6wA-3ilrA:
19.19
3r6wB-3ilrA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R6W_A_NFZA214_1
(FMN-DEPENDENT
NADH-AZOREDUCTASE 1)		 3ilr HEPARIN LYASE I
(Bacteroides
thetaiotaomicron) 		5 / 10 PHE A 238
PHE A 295
PHE A 131
PHE A 352
GLY A 355
 None
 1.36A 3r6wA-3ilrA:
undetectable
3r6wB-3ilrA:
undetectable		 3r6wA-3ilrA:
19.19
3r6wB-3ilrA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 3ilr HEPARIN LYASE I
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 317
THR A 277
ALA A 279
ILE A 334
ILE A 240
 None
 1.12A 3ut5B-3ilrA:
undetectable		 3ut5B-3ilrA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3ilr HEPARIN LYASE I
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 343
ILE A 299
GLY A 315
ILE A 340
GLY A 305
 None
 0.98A 5d4uC-3ilrA:
undetectable		 5d4uC-3ilrA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3ilr HEPARIN LYASE I
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 343
ILE A 299
GLY A 315
ILE A 340
GLY A 305
 None
 0.95A 5d4uD-3ilrA:
undetectable		 5d4uD-3ilrA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_B_SAMB601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 3ilr HEPARIN LYASE I
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 117
ASP A  95
SER A  25
VAL A  37
VAL A  19
 None
None
EDO  A   5 ( 4.5A)
None
None
 1.06A 5dpdB-3ilrA:
undetectable		 5dpdB-3ilrA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 3ilr HEPARIN LYASE I
(Bacteroides
thetaiotaomicron) 		5 / 11 PHE A 231
VAL A 297
ILE A 299
TRP A 150
ILE A 340
 None
 0.96A 5hw8E-3ilrA:
undetectable		 5hw8E-3ilrA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 3ilr HEPARIN LYASE I
(Bacteroides
thetaiotaomicron) 		5 / 12 PHE A 231
VAL A 297
ILE A 299
TRP A 150
ILE A 340
 None
 0.99A 5hw8B-3ilrA:
undetectable
5hw8F-3ilrA:
undetectable
5hw8G-3ilrA:
undetectable		 5hw8B-3ilrA:
14.71
5hw8F-3ilrA:
14.71
5hw8G-3ilrA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 3ilr HEPARIN LYASE I
(Bacteroides
thetaiotaomicron) 		5 / 9 LEU A 229
ALA A 230
PHE A 231
VAL A 297
ILE A 299
 None
SGN  A 377 ( 3.9A)
None
None
None
 1.08A 5om2A-3ilrA:
undetectable
5om2B-3ilrA:
undetectable		 5om2A-3ilrA:
12.22
5om2B-3ilrA:
6.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ilr HEPARIN LYASE I
(Bacteroides
thetaiotaomicron) 		5 / 10 VAL A 297
VAL A 319
LEU A 229
ALA A 230
PRO A 228
 None
None
None
SGN  A 377 ( 3.9A)
None
 1.26A 5tt3C-3ilrA:
undetectable		 5tt3C-3ilrA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3ilr HEPARIN LYASE I
(Bacteroides
thetaiotaomicron) 		3 / 3 GLY A 349
THR A 277
PRO A 228
 None
 0.50A 5v5zA-3ilrA:
undetectable		 5v5zA-3ilrA:
22.18