SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3im0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB8_0
(GRAMICIDIN A)		 3im0 VAL-1
(Paramecium
bursaria
Chlorella
virus
CVK2) 		3 / 3 VAL A  79
VAL A  39
TRP A  77
 None
 0.85A 1bdwA-3im0A:
undetectable
1bdwB-3im0A:
undetectable		 1bdwA-3im0A:
5.33
1bdwB-3im0A:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E6W_C_ESTC302_1
(SHORT CHAIN
3-HYDROXYACYL-COA
DEHYDROGENASE)		 3im0 VAL-1
(Paramecium
bursaria
Chlorella
virus
CVK2) 		4 / 4 ALA A 233
GLN A 231
TYR A  44
LEU A 160
 None
 1.28A 1e6wC-3im0A:
undetectable		 1e6wC-3im0A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 3im0 VAL-1
(Paramecium
bursaria
Chlorella
virus
CVK2) 		4 / 5 ILE A 117
PHE A 156
PHE A 152
ILE A 191
 None
 0.95A 2hjhA-3im0A:
undetectable		 2hjhA-3im0A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DLC_A_SAMA220_0
(PUTATIVE
S-ADENOSYL-L-METHION
INE-DEPENDENT
METHYLTRANSFERASE)		 3im0 VAL-1
(Paramecium
bursaria
Chlorella
virus
CVK2) 		5 / 12 TYR A 106
GLY A  49
GLY A 222
ASP A  45
VAL A  56
 BDP  A 301 (-4.0A)
None
None
None
None
 1.40A 3dlcA-3im0A:
undetectable		 3dlcA-3im0A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB201_1
(PROTEIN S100-A4)		 3im0 VAL-1
(Paramecium
bursaria
Chlorella
virus
CVK2) 		4 / 8 ILE A 117
PHE A  61
PHE A 235
PHE A  59
 None
 0.97A 3ko0B-3im0A:
undetectable
3ko0J-3im0A:
undetectable		 3ko0B-3im0A:
17.36
3ko0J-3im0A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 3im0 VAL-1
(Paramecium
bursaria
Chlorella
virus
CVK2) 		4 / 8 PHE A 221
GLY A  91
GLY A  55
ASN A 230
 None
 1.00A 3v3nC-3im0A:
undetectable		 3v3nC-3im0A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 3im0 VAL-1
(Paramecium
bursaria
Chlorella
virus
CVK2) 		3 / 3 TYR A 128
PHE A 220
ARG A 116
 BDP  A 301 (-4.6A)
BDP  A 301 (-4.6A)
BDP  A 301 (-2.6A)
 1.23A 4g19D-3im0A:
undetectable		 4g19D-3im0A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 3im0 VAL-1
(Paramecium
bursaria
Chlorella
virus
CVK2) 		3 / 3 TYR A 130
PHE A 220
ARG A 116
 BDP  A 301 (-4.5A)
BDP  A 301 (-4.6A)
BDP  A 301 (-2.6A)
 1.21A 4g19D-3im0A:
undetectable		 4g19D-3im0A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)		 3im0 VAL-1
(Paramecium
bursaria
Chlorella
virus
CVK2) 		3 / 3 ASP A 216
TRP A 119
SER A 114
 None
 1.03A 4lrhA-3im0A:
undetectable		 4lrhA-3im0A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3im0 VAL-1
(Paramecium
bursaria
Chlorella
virus
CVK2) 		3 / 3 LEU A   7
THR A 219
ASN A 218
 None
 0.73A 6baaE-3im0A:
undetectable		 6baaE-3im0A:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3im0 VAL-1
(Paramecium
bursaria
Chlorella
virus
CVK2) 		3 / 3 LEU A   7
THR A 219
ASN A 218
 None
 0.73A 6baaF-3im0A:
undetectable		 6baaF-3im0A:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3im0 VAL-1
(Paramecium
bursaria
Chlorella
virus
CVK2) 		3 / 3 LEU A   7
THR A 219
ASN A 218
 None
 0.74A 6baaG-3im0A:
undetectable		 6baaG-3im0A:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3im0 VAL-1
(Paramecium
bursaria
Chlorella
virus
CVK2) 		3 / 3 LEU A   7
THR A 219
ASN A 218
 None
 0.73A 6baaH-3im0A:
undetectable		 6baaH-3im0A:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 3im0 VAL-1
(Paramecium
bursaria
Chlorella
virus
CVK2) 		3 / 3 SER A  48
SER A 227
ALA A 233
 None
 0.68A 6dwnC-3im0A:
undetectable		 6dwnC-3im0A:
21.66