SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3im9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 3im9 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Staphylococcus
aureus) 		5 / 12 SER A  89
ILE A 110
ILE A 214
PHE A 210
GLN A 248
 None
None
None
CA  A 601 ( 4.9A)
CA  A 601 (-3.5A)
 0.97A 1qhsA-3im9A:
undetectable		 1qhsA-3im9A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 3im9 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Staphylococcus
aureus) 		5 / 12 SER A  89
ILE A 110
ILE A 214
PHE A 210
GLN A 248
 None
None
None
CA  A 601 ( 4.9A)
CA  A 601 (-3.5A)
 0.97A 1qhyA-3im9A:
undetectable		 1qhyA-3im9A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_A_DESA129_1
(TRANSTHYRETIN)		 3im9 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Staphylococcus
aureus) 		4 / 4 LYS A 152
LEU A 173
LEU A 147
SER A 146
 None
 1.13A 1tt6A-3im9A:
undetectable		 1tt6A-3im9A:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_B_DESB128_1
(TRANSTHYRETIN)		 3im9 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Staphylococcus
aureus) 		4 / 5 LYS A 152
LEU A 173
LEU A 147
SER A 146
 None
 1.14A 1tt6B-3im9A:
undetectable		 1tt6B-3im9A:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 3im9 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Staphylococcus
aureus) 		4 / 5 ASP A  51
GLU A  53
THR A  62
LEU A  56
 None
 1.04A 1u18B-3im9A:
undetectable		 1u18B-3im9A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDT_A_VIAA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3im9 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Staphylococcus
aureus) 		5 / 12 ASN A 229
TYR A 250
ALA A 107
ILE A 110
PHE A 210
 None
None
None
None
CA  A 601 ( 4.9A)
 1.24A 1udtA-3im9A:
undetectable		 1udtA-3im9A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3im9 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Staphylococcus
aureus) 		4 / 5 LEU A  22
ALA A  75
ILE A  32
SER A  71
 None
 1.16A 2othA-3im9A:
undetectable		 2othA-3im9A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3im9 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Staphylococcus
aureus) 		5 / 12 LEU A  96
LEU A 102
ALA A 107
VAL A 111
LEU A  56
 None
 1.31A 3b0wA-3im9A:
undetectable		 3b0wA-3im9A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_B_LOCB700_2
(TUBULIN BETA-2B
CHAIN)		 3im9 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Staphylococcus
aureus) 		5 / 11 LEU A 135
ALA A 186
LYS A 182
LEU A 184
VAL A 167
 None
 1.29A 3e22B-3im9A:
undetectable		 3e22B-3im9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3im9 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Staphylococcus
aureus) 		5 / 10 GLY A 115
ASN A 158
VAL A 253
GLN A 248
PHE A 210
 None
None
None
CA  A 601 (-3.5A)
CA  A 601 ( 4.9A)
 1.39A 4fgkA-3im9A:
undetectable
4fgkB-3im9A:
1.7		 4fgkA-3im9A:
22.96
4fgkB-3im9A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_B_4TXB201_1
(TRANSTHYRETIN)		 3im9 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Staphylococcus
aureus) 		4 / 7 LYS A 152
LEU A 173
LEU A 147
SER A 146
 None
 1.04A 5bojB-3im9A:
undetectable		 5bojB-3im9A:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3im9 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Staphylococcus
aureus) 		5 / 6 ILE A 174
ALA A 157
VAL A 167
VAL A 194
HIS A 199
 None
None
None
ACT  A 801 (-4.2A)
None
 1.42A 5eclD-3im9A:
undetectable		 5eclD-3im9A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3im9 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Staphylococcus
aureus) 		5 / 12 THR A  59
GLN A  11
THR A 124
GLY A  57
PHE A 198
 ACT  A 801 (-3.9A)
ACT  A 801 ( 3.8A)
None
None
ACT  A 801 (-4.4A)
 1.32A 5m66C-3im9A:
undetectable		 5m66C-3im9A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 3im9 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Staphylococcus
aureus) 		5 / 9 LEU A  40
VAL A 111
ILE A  32
MET A  48
LEU A  45
 None
 1.01A 5og9A-3im9A:
undetectable		 5og9A-3im9A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_0
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 3im9 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Staphylococcus
aureus) 		5 / 12 GLY A  91
VAL A 111
MET A  86
GLN A  63
HIS A  88
 None
None
None
None
SO4  A 901 (-3.6A)
 1.22A 5ubbA-3im9A:
undetectable		 5ubbA-3im9A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 3im9 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Staphylococcus
aureus) 		3 / 3 LYS A  15
LEU A  33
ASP A  21
 None
 0.92A 5zv2A-3im9A:
undetectable		 5zv2A-3im9A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA813_0
(GEPHYRIN)		 3im9 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Staphylococcus
aureus) 		3 / 3 THR A  68
ALA A  36
LYS A  38
 None
 0.76A 6fgcA-3im9A:
undetectable		 6fgcA-3im9A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA817_0
(GEPHYRIN)		 3im9 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Staphylococcus
aureus) 		3 / 3 THR A  68
ALA A  36
LYS A  38
 None
 0.74A 6fgdA-3im9A:
undetectable		 6fgdA-3im9A:
21.55