SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ima'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_ACTA421_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 3ima CYSTEINE PROTEINASE
INHIBITOR
(Colocasia
esculenta) 		4 / 8 GLY B   6
GLY B   5
MET B   4
LEU B   3
 None
 0.53A 1qzzA-3imaB:
undetectable		 1qzzA-3imaB:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3ima CYSTEINE PROTEINASE
INHIBITOR
(Colocasia
esculenta) 		5 / 12 ALA B  73
PHE B  89
LEU B  38
ALA B  23
VAL B  62
 None
 1.06A 3rukA-3imaB:
undetectable		 3rukA-3imaB:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3ima CYSTEINE PROTEINASE
INHIBITOR
(Colocasia
esculenta) 		3 / 3 HIS B  57
SER B  90
GLU B  88
 None
 0.89A 3s8pA-3imaB:
undetectable		 3s8pA-3imaB:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA5_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3ima CYSTEINE PROTEINASE
INHIBITOR
(Colocasia
esculenta) 		3 / 3 LYS B  85
SER B  52
GLN B  78
 None
 1.25A 3si7A-3imaB:
undetectable		 3si7A-3imaB:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 3ima CYSTEINE PROTEINASE
INHIBITOR
(Colocasia
esculenta) 		3 / 3 LEU B  37
VAL B  27
ASP B  28
 None
 0.64A 4y8wC-3imaB:
undetectable		 4y8wC-3imaB:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 3ima CYSTEINE PROTEINASE
INHIBITOR
(Colocasia
esculenta) 		4 / 6 TYR B  71
LYS B  69
GLY B  65
LEU B  38
 None
 1.13A 5bphD-3imaB:
undetectable		 5bphD-3imaB:
15.28