SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3imf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_A_RBFA100_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3imf SHORT CHAIN
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 11 SER A 119
THR A 115
THR A  33
ILE A  32
VAL A  31
 None
 1.25A 1pkvA-3imfA:
undetectable
1pkvB-3imfA:
undetectable		 1pkvA-3imfA:
20.00
1pkvB-3imfA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_B_RBFB101_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3imf SHORT CHAIN
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 11 VAL A  31
SER A 119
THR A 115
THR A  33
ILE A  32
 None
 1.22A 1pkvA-3imfA:
undetectable
1pkvB-3imfA:
undetectable		 1pkvA-3imfA:
20.00
1pkvB-3imfA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 3imf SHORT CHAIN
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 12 GLY A  11
SER A  12
GLY A  14
MET A  15
ILE A  83
 None
 0.83A 2b25B-3imfA:
5.9		 2b25B-3imfA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 3imf SHORT CHAIN
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 12 TYR A 142
SER A 153
VAL A 111
VAL A 107
HIS A 152
 None
 1.29A 3bjmA-3imfA:
undetectable		 3bjmA-3imfA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 3imf SHORT CHAIN
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 12 TYR A 142
SER A 153
VAL A 111
VAL A 107
HIS A 152
 None
 1.27A 3bjmB-3imfA:
undetectable		 3bjmB-3imfA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 3imf SHORT CHAIN
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 12 TYR A 142
SER A 153
VAL A 111
VAL A 107
HIS A 152
 None
 1.29A 3w2tA-3imfA:
4.1		 3w2tA-3imfA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 3imf SHORT CHAIN
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 12 TYR A 142
SER A 153
VAL A 111
VAL A 107
HIS A 152
 None
 1.28A 3w2tB-3imfA:
4.1		 3w2tB-3imfA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3imf SHORT CHAIN
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 12 LEU A 224
LEU A 228
CYH A 229
ILE A  85
ILE A 182
 None
 1.09A 4a7aB-3imfA:
3.4		 4a7aB-3imfA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 3imf SHORT CHAIN
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 12 TYR A 142
SER A 153
VAL A 111
VAL A 107
HIS A 152
 None
 1.37A 4ffwA-3imfA:
4.5		 4ffwA-3imfA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 3imf SHORT CHAIN
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 12 TYR A 142
SER A 153
VAL A 111
VAL A 107
HIS A 152
 None
 1.34A 4ffwB-3imfA:
4.5		 4ffwB-3imfA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_1
(PROTEASE)		 3imf SHORT CHAIN
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 11 GLY A  18
ALA A  20
THR A   9
GLY A  10
THR A  56
 None
 0.97A 4qgiA-3imfA:
undetectable		 4qgiA-3imfA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3imf SHORT CHAIN
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 12 GLY A  18
ILE A  47
GLY A  11
ILE A   8
GLY A 191
 None
 0.97A 5d4uD-3imfA:
6.8		 5d4uD-3imfA:
25.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3imf SHORT CHAIN
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 12 ILE A  67
VAL A  57
THR A  33
ASN A  87
ILE A   7
 None
 1.09A 5lg3J-3imfA:
undetectable		 5lg3J-3imfA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 3imf SHORT CHAIN
DEHYDROGENASE
(Bacillus
anthracis) 		5 / 12 TYR A 142
SER A 153
VAL A 111
VAL A 107
HIS A 152
 None
 1.29A 6b1eB-3imfA:
undetectable		 6b1eB-3imfA:
14.97