SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3imi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_E_NCAE507_0
(NAD-DEPENDENT
DEACETYLASE 2)		 3imi HIT FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 7 ILE A  35
PHE A  32
LEU A  44
ILE A  18
 None
 0.95A 1yc2E-3imiA:
undetectable		 1yc2E-3imiA:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O1C_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 3imi HIT FAMILY PROTEIN
(Bacillus
anthracis) 		8 / 10 ILE A   9
PHE A  10
ILE A  13
ASP A  34
ILE A  35
LEU A  44
HIS A 103
HIS A 105
 None
None
None
None
None
None
SO4  A 145 (-3.8A)
SO4  A 145 (-4.1A)
 0.61A 3o1cA-3imiA:
15.5		 3o1cA-3imiA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O1C_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 3imi HIT FAMILY PROTEIN
(Bacillus
anthracis) 		5 / 10 ILE A   9
PHE A  10
ILE A  13
ILE A  35
SER A  36
 None
 0.98A 3o1cA-3imiA:
15.5		 3o1cA-3imiA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O1X_A_ADNA1450_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 3imi HIT FAMILY PROTEIN
(Bacillus
anthracis) 		8 / 10 ILE A   9
PHE A  10
ILE A  13
ASP A  34
ILE A  35
LEU A  44
HIS A 103
HIS A 105
 None
None
None
None
None
None
SO4  A 145 (-3.8A)
SO4  A 145 (-4.1A)
 0.62A 3o1xA-3imiA:
15.4		 3o1xA-3imiA:
32.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 3imi HIT FAMILY PROTEIN
(Bacillus
anthracis) 		8 / 10 ILE A   9
PHE A  10
ILE A  13
ASP A  34
ILE A  35
LEU A  44
HIS A 103
HIS A 105
 None
None
None
None
None
None
SO4  A 145 (-3.8A)
SO4  A 145 (-4.1A)
 0.60A 3qgzA-3imiA:
15.6		 3qgzA-3imiA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_A_FUAA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3imi HIT FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 5 ILE A  72
ILE A  65
HIS A  28
VAL A  29
 None
 1.00A 5jmnA-3imiA:
2.2		 5jmnA-3imiA:
8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_A_FUAA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3imi HIT FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 5 ILE A  72
ILE A  65
HIS A  64
VAL A  29
 None
 0.82A 5jmnA-3imiA:
2.2		 5jmnA-3imiA:
8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM8_B_L8PB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 3imi HIT FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 8 ASN A  90
GLN A  97
HIS A 103
HIS A 105
 SO4  A 145 (-3.9A)
None
SO4  A 145 (-3.8A)
SO4  A 145 (-4.1A)
 0.21A 5km8A-3imiA:
12.7
5km8B-3imiA:
16.0		 5km8A-3imiA:
26.67
5km8B-3imiA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM9_B_ADNB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 3imi HIT FAMILY PROTEIN
(Bacillus
anthracis) 		7 / 12 ILE A   9
PHE A  10
ILE A  13
ASP A  34
LEU A  44
HIS A 103
HIS A 105
 None
None
None
None
None
SO4  A 145 (-3.8A)
SO4  A 145 (-4.1A)
 0.55A 5km9B-3imiA:
16.1		 5km9B-3imiA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM9_B_ADNB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 3imi HIT FAMILY PROTEIN
(Bacillus
anthracis) 		5 / 12 ILE A  13
PHE A  10
ILE A  46
LEU A  30
ASP A  34
 None
 1.03A 5km9B-3imiA:
16.1		 5km9B-3imiA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM9_B_ADNB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 3imi HIT FAMILY PROTEIN
(Bacillus
anthracis) 		7 / 12 PHE A  10
ILE A  13
ASP A  34
LEU A  44
VAL A  99
HIS A 103
HIS A 105
 None
None
None
None
SO4  A 145 (-4.4A)
SO4  A 145 (-3.8A)
SO4  A 145 (-4.1A)
 0.42A 5km9B-3imiA:
16.1		 5km9B-3imiA:
26.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UVM_B_ADNB207_1
(HISTIDINE TRIAD
(HIT) PROTEIN)		 3imi HIT FAMILY PROTEIN
(Bacillus
anthracis) 		9 / 12 PHE A  10
ILE A  13
ASP A  34
ILE A  35
LEU A  44
THR A  98
VAL A  99
HIS A 103
HIS A 105
 None
None
None
None
None
SO4  A 145 (-2.8A)
SO4  A 145 (-4.4A)
SO4  A 145 (-3.8A)
SO4  A 145 (-4.1A)
 0.48A 5uvmB-3imiA:
16.4		 5uvmB-3imiA:
32.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 3imi HIT FAMILY PROTEIN
(Bacillus
anthracis) 		4 / 5 LEU A 106
THR A  43
THR A  39
GLY A  41
 None
 0.99A 6gtqA-3imiA:
2.8		 6gtqA-3imiA:
23.62