SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3imk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 3imk PUTATIVE MOLYBDENUM
CARRIER PROTEIN
(Syntrophus
aciditrophicus) 		4 / 7 ILE A 110
ILE A  78
LEU A  77
ILE A  79
 GOL  A 159 ( 4.1A)
None
None
None
 0.85A 2q83A-3imkA:
undetectable		 2q83A-3imkA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_C_IBPC1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 3imk PUTATIVE MOLYBDENUM
CARRIER PROTEIN
(Syntrophus
aciditrophicus) 		5 / 10 THR A  66
ILE A  78
LEU A  77
GLY A  75
THR A  91
 GOL  A 158 ( 4.2A)
None
None
None
GOL  A 158 (-4.4A)
 1.23A 2wd9C-3imkA:
3.9		 2wd9C-3imkA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 3imk PUTATIVE MOLYBDENUM
CARRIER PROTEIN
(Syntrophus
aciditrophicus) 		4 / 6 VAL A  37
GLN A  15
GLY A 135
LEU A  84
 None
None
GOL  A 158 (-4.1A)
None
 0.89A 3bjwE-3imkA:
undetectable		 3bjwE-3imkA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_1
(RENIN)		 3imk PUTATIVE MOLYBDENUM
CARRIER PROTEIN
(Syntrophus
aciditrophicus) 		5 / 12 GLY A  13
THR A  76
LEU A  23
ASP A  19
ALA A  22
 GOL  A 158 (-3.7A)
None
None
GOL  A 158 (-2.9A)
None
 1.11A 3d91A-3imkA:
undetectable		 3d91A-3imkA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O02_B_JN3B1_1
(CELL INVASION
PROTEIN SIPD)		 3imk PUTATIVE MOLYBDENUM
CARRIER PROTEIN
(Syntrophus
aciditrophicus) 		5 / 10 ILE A 110
ALA A 116
LEU A 107
LEU A 151
VAL A 154
 GOL  A 159 ( 4.1A)
None
None
None
None
 1.13A 3o02A-3imkA:
undetectable
3o02B-3imkA:
undetectable		 3o02A-3imkA:
20.90
3o02B-3imkA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 3imk PUTATIVE MOLYBDENUM
CARRIER PROTEIN
(Syntrophus
aciditrophicus) 		5 / 12 LEU A  77
THR A  76
GLY A 135
ALA A  18
ALA A  22
 None
None
GOL  A 158 (-4.1A)
None
None
 0.90A 3p5nA-3imkA:
undetectable		 3p5nA-3imkA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 3imk PUTATIVE MOLYBDENUM
CARRIER PROTEIN
(Syntrophus
aciditrophicus) 		5 / 12 LEU A  77
THR A  76
GLY A 135
ALA A  18
ALA A  22
 None
None
GOL  A 158 (-4.1A)
None
None
 0.89A 3p5nB-3imkA:
undetectable		 3p5nB-3imkA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_A_ZMRA700_1
(NEURAMINIDASE)		 3imk PUTATIVE MOLYBDENUM
CARRIER PROTEIN
(Syntrophus
aciditrophicus) 		5 / 12 ARG A  65
ASP A  19
ALA A 138
GLU A  44
TYR A  62
 GOL  A 158 (-3.2A)
GOL  A 158 (-2.9A)
MES  A 160 (-3.6A)
None
None
 1.20A 4cpnA-3imkA:
undetectable		 4cpnA-3imkA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 3imk PUTATIVE MOLYBDENUM
CARRIER PROTEIN
(Syntrophus
aciditrophicus) 		5 / 8 THR A  66
GLY A  13
GLN A  15
VAL A  37
PRO A  38
 GOL  A 158 ( 4.2A)
GOL  A 158 (-3.7A)
None
None
None
 1.46A 4e1vG-3imkA:
undetectable		 4e1vG-3imkA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3imk PUTATIVE MOLYBDENUM
CARRIER PROTEIN
(Syntrophus
aciditrophicus) 		6 / 12 ALA A 138
GLY A 135
PRO A 136
LEU A  77
ILE A  10
LEU A 152
 MES  A 160 (-3.6A)
GOL  A 158 (-4.1A)
None
None
None
None
 1.34A 4n49A-3imkA:
undetectable		 4n49A-3imkA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 3imk PUTATIVE MOLYBDENUM
CARRIER PROTEIN
(Syntrophus
aciditrophicus) 		4 / 7 ASN A 132
LEU A 152
LEU A  23
ILE A  79
 None
 0.99A 4okwA-3imkA:
undetectable		 4okwA-3imkA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3imk PUTATIVE MOLYBDENUM
CARRIER PROTEIN
(Syntrophus
aciditrophicus) 		5 / 12 ALA A 115
ALA A  18
ILE A  79
ILE A  10
LEU A 131
 None
 1.20A 4r3aA-3imkA:
undetectable		 4r3aA-3imkA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 3imk PUTATIVE MOLYBDENUM
CARRIER PROTEIN
(Syntrophus
aciditrophicus) 		5 / 12 SER A  12
ASP A  19
GLY A  17
ILE A  10
LEU A 152
 None
GOL  A 158 (-2.9A)
MES  A 160 (-3.5A)
None
None
 0.96A 6dwnC-3imkA:
undetectable		 6dwnC-3imkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_C_ADNC502_1
(-)		 3imk PUTATIVE MOLYBDENUM
CARRIER PROTEIN
(Syntrophus
aciditrophicus) 		5 / 12 HIS A 104
ASP A 106
ASP A 141
LEU A  84
GLY A 135
 None
None
None
None
GOL  A 158 (-4.1A)
 1.44A 6f3mC-3imkA:
undetectable		 6f3mC-3imkA:
17.98