SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3iml'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BRP_A_RTLA183_0
(RETINOL BINDING
PROTEIN)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 299
GLY A 257
PHE A   7
TYR A 255
PHE A 319
 None
 1.32A 1brpA-3imlA:
undetectable		 1brpA-3imlA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYR_A_TOPA407_1
(DIHYDROFOLATE
REDUCTASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 11 ALA A  70
LEU A  54
ILE A  58
ILE A  64
THR A  73
 None
 1.00A 1dyrA-3imlA:
undetectable		 1dyrA-3imlA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 8 PHE A 266
ASP A 275
GLY A 263
GLY A 262
 None
 0.91A 1ekjE-3imlA:
undetectable
1ekjF-3imlA:
undetectable		 1ekjE-3imlA:
21.61
1ekjF-3imlA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 12 TRP A 163
GLN A 192
GLY A  15
ASN A 229
ILE A 211
 None
 1.17A 1kxhA-3imlA:
undetectable		 1kxhA-3imlA:
23.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		7 / 8 HIS A  16
PRO A  17
ASP A 167
LYS A 169
SER A 190
THR A 231
PHE A 234
 None
 0.68A 1p7lC-3imlA:
54.0		 1p7lC-3imlA:
69.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		6 / 8 HIS A  16
PRO A  17
LYS A 169
SER A 190
THR A 231
ASP A 242
 None
 1.08A 1p7lC-3imlA:
54.0		 1p7lC-3imlA:
69.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P7L_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 8 ALA A  42
GLU A  57
ASP A 122
LYS A 273
 None
 0.61A 1p7lD-3imlA:
54.0		 1p7lD-3imlA:
69.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		7 / 8 HIS A  16
PRO A  17
ASP A 167
LYS A 169
SER A 190
THR A 231
PHE A 234
 None
 0.69A 1p7lD-3imlA:
54.0		 1p7lD-3imlA:
69.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		6 / 8 HIS A  16
PRO A  17
LYS A 169
SER A 190
THR A 231
ASP A 242
 None
 1.07A 1p7lD-3imlA:
54.0		 1p7lD-3imlA:
69.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		7 / 8 HIS A  16
PRO A  17
ASP A 167
LYS A 169
SER A 190
THR A 231
PHE A 234
 None
 0.70A 1rg9A-3imlA:
54.1		 1rg9A-3imlA:
69.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		6 / 8 HIS A  16
PRO A  17
LYS A 169
SER A 190
THR A 231
ASP A 242
 None
 1.10A 1rg9A-3imlA:
54.1		 1rg9A-3imlA:
69.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RG9_A_SAMA385_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 8 ALA A  42
GLU A  57
ASP A 122
LYS A 273
 None
 0.62A 1rg9B-3imlA:
54.1		 1rg9B-3imlA:
69.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RG9_B_SAMB485_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 8 ALA A  42
GLU A  57
ASP A 122
LYS A 273
 None
 0.62A 1rg9A-3imlA:
54.1		 1rg9A-3imlA:
69.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		7 / 8 HIS A  16
PRO A  17
ASP A 167
LYS A 169
SER A 190
THR A 231
PHE A 234
 None
 0.70A 1rg9B-3imlA:
54.1		 1rg9B-3imlA:
69.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		6 / 8 HIS A  16
PRO A  17
LYS A 169
SER A 190
THR A 231
ASP A 242
 None
 1.10A 1rg9B-3imlA:
54.1		 1rg9B-3imlA:
69.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		7 / 8 HIS A  16
PRO A  17
ASP A 167
LYS A 169
SER A 190
THR A 231
PHE A 234
 None
 0.71A 1rg9C-3imlA:
54.0		 1rg9C-3imlA:
69.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		6 / 8 HIS A  16
PRO A  17
LYS A 169
SER A 190
THR A 231
ASP A 242
 None
 1.11A 1rg9C-3imlA:
54.0		 1rg9C-3imlA:
69.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RG9_C_SAMC585_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 8 ALA A  42
GLU A  57
ASP A 122
LYS A 273
 None
 0.60A 1rg9D-3imlA:
18.3		 1rg9D-3imlA:
69.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RG9_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 8 ALA A  42
GLU A  57
ASP A 122
LYS A 273
 None
 0.62A 1rg9C-3imlA:
54.0		 1rg9C-3imlA:
69.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		7 / 8 HIS A  16
PRO A  17
ASP A 167
LYS A 169
SER A 190
THR A 231
PHE A 234
 None
 0.72A 1rg9D-3imlA:
18.3		 1rg9D-3imlA:
69.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		6 / 8 HIS A  16
PRO A  17
LYS A 169
SER A 190
THR A 231
ASP A 242
 None
 1.10A 1rg9D-3imlA:
18.3		 1rg9D-3imlA:
69.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 5 LEU A  29
ASP A  26
GLY A 247
ALA A  43
 None
 0.83A 2aohA-3imlA:
undetectable		 2aohA-3imlA:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BL9_A_CP6A1240_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 12 ALA A  70
LEU A  54
ILE A  58
ILE A  64
THR A  73
 None
 1.16A 2bl9A-3imlA:
undetectable		 2bl9A-3imlA:
22.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		6 / 8 HIS A  16
PRO A  17
ASP A 167
LYS A 169
SER A 190
PHE A 234
 None
 0.27A 2obvA-3imlA:
53.0		 2obvA-3imlA:
56.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 8 HIS A  16
PRO A  17
LYS A 169
SER A 190
ASP A 242
 None
 0.87A 2obvA-3imlA:
53.0		 2obvA-3imlA:
56.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		6 / 8 HIS A  16
PRO A  17
ASP A 167
LYS A 169
SER A 190
PHE A 234
 None
 0.30A 2p02A-3imlA:
40.4		 2p02A-3imlA:
53.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 8 HIS A  16
PRO A  17
LYS A 169
SER A 190
ASP A 242
 None
 0.86A 2p02A-3imlA:
40.4		 2p02A-3imlA:
53.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		6 / 12 GLY A 128
GLY A 282
ILE A 289
ALA A 259
VAL A 316
LEU A 299
 None
 1.47A 2yqzA-3imlA:
undetectable		 2yqzA-3imlA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 11 GLY A  15
GLY A 238
ASP A 167
ALA A 168
ALA A 153
 None
 1.03A 3g88A-3imlA:
undetectable		 3g88A-3imlA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 11 GLY A  15
GLY A 238
ASP A 167
ALA A 168
ALA A 153
 None
 1.02A 3g88B-3imlA:
undetectable		 3g88B-3imlA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 12 GLY A  15
GLY A 238
ASP A 167
ALA A 168
ALA A 153
 None
 1.05A 3g89A-3imlA:
undetectable		 3g89A-3imlA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 11 GLY A  15
GLY A 238
ASP A 167
ALA A 168
ALA A 153
 None
 1.05A 3g89B-3imlA:
undetectable		 3g89B-3imlA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 12 GLY A  15
GLY A 238
ASP A 167
ALA A 168
ALA A 153
 None
 1.08A 3g8bA-3imlA:
undetectable		 3g8bA-3imlA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 12 GLY A  15
GLY A 238
ASP A 167
ALA A 168
ALA A 153
 None
 1.05A 3g8bB-3imlA:
undetectable		 3g8bB-3imlA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQZ_A_LQZA586_1
(SERUM ALBUMIN)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 6 ARG A 248
ASP A  18
LYS A 249
LYS A 169
 None
 1.45A 3jqzA-3imlA:
0.3		 3jqzA-3imlA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQ8_A_TOPA2001_1
(DIHYDROFOLATE
REDUCTASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 9 ALA A  70
LEU A  54
ILE A  58
ILE A  64
THR A  73
 None
 1.13A 3tq8A-3imlA:
undetectable		 3tq8A-3imlA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQB_A_FOLA2001_0
(DIHYDROFOLATE
REDUCTASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 11 ALA A  70
LEU A  54
ILE A  58
ILE A  64
THR A  73
 None
 1.10A 3tqbA-3imlA:
undetectable		 3tqbA-3imlA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 8 HIS A  16
PRO A  17
ASP A 167
LYS A 169
 None
 0.29A 4k0bB-3imlA:
26.9		 4k0bB-3imlA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 8 HIS A  16
PRO A  17
LYS A 169
ASP A 242
 None
 0.99A 4k0bB-3imlA:
26.9		 4k0bB-3imlA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR3_A_GLYA701_0
(GLYCINE--TRNA LIGASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 6 ARG A 147
GLU A 367
ARG A 283
GLU A 374
 None
 1.11A 4kr3A-3imlA:
undetectable		 4kr3A-3imlA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 8 ARG A 366
ASP A  30
GLU A 370
ARG A 276
 None
 1.33A 4kr4C-3imlA:
undetectable		 4kr4C-3imlA:
21.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		6 / 8 HIS A  16
PRO A  17
ASP A 167
LYS A 169
SER A 190
PHE A 234
 None
 0.23A 4kttA-3imlA:
36.8		 4kttA-3imlA:
53.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 8 HIS A  16
PRO A  17
LYS A 169
SER A 190
ASP A 242
 None
 0.92A 4kttA-3imlA:
36.8		 4kttA-3imlA:
53.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 8 ALA A  42
GLU A  57
ASP A 122
LYS A 273
 None
 0.62A 4kttB-3imlA:
52.0		 4kttB-3imlA:
53.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		6 / 8 HIS A  16
PRO A  17
ASP A 167
LYS A 169
SER A 190
PHE A 234
 None
 0.27A 4kttC-3imlA:
50.8		 4kttC-3imlA:
53.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 8 HIS A  16
PRO A  17
LYS A 169
SER A 190
ASP A 242
 None
 0.90A 4kttC-3imlA:
50.8		 4kttC-3imlA:
53.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 8 ALA A  42
GLU A  57
ASP A 122
LYS A 273
 None
 0.44A 4kttD-3imlA:
52.3		 4kttD-3imlA:
53.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KTV_A_ADNA403_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		6 / 12 HIS A  16
PRO A  17
ASP A 167
LYS A 169
SER A 190
PHE A 234
 None
 0.26A 4ktvA-3imlA:
51.1
4ktvB-3imlA:
52.0		 4ktvA-3imlA:
53.49
4ktvB-3imlA:
53.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KTV_C_ADNC403_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 11 HIS A  16
PRO A  17
ASP A 167
LYS A 169
PHE A 234
 None
 0.31A 4ktvC-3imlA:
50.4
4ktvD-3imlA:
51.8		 4ktvC-3imlA:
53.49
4ktvD-3imlA:
53.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 8 HIS A  16
PRO A  17
ASP A 167
LYS A 169
 None
 0.28A 4l7iB-3imlA:
26.7		 4l7iB-3imlA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 8 HIS A  16
PRO A  17
LYS A 169
ASP A 242
 None
 0.95A 4l7iB-3imlA:
26.7		 4l7iB-3imlA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA610_0
(SERUM ALBUMIN)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		3 / 3 VAL A 324
SER A 325
THR A 328
 None
 0.28A 4luhA-3imlA:
undetectable		 4luhA-3imlA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 9 PRO A  17
VAL A  20
ALA A  21
GLY A  50
GLY A 244
 None
 1.30A 4mmbA-3imlA:
undetectable		 4mmbA-3imlA:
21.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		6 / 8 HIS A  16
PRO A  17
ASP A 167
LYS A 169
SER A 190
PHE A 234
 None
 0.23A 4ndnA-3imlA:
51.4		 4ndnA-3imlA:
53.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 8 HIS A  16
PRO A  17
LYS A 169
SER A 190
ASP A 242
 None
 0.92A 4ndnA-3imlA:
51.4		 4ndnA-3imlA:
53.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 8 ALA A  42
GLU A  57
ASP A 122
LYS A 273
 None
 0.62A 4ndnB-3imlA:
52.2		 4ndnB-3imlA:
53.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NDN_C_SAMC405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 7 HIS A  16
PRO A  17
ASP A 167
LYS A 169
PHE A 234
 None
 0.25A 4ndnC-3imlA:
50.9		 4ndnC-3imlA:
53.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NDN_C_SAMC405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 7 HIS A  16
PRO A  17
LYS A 169
ASP A 242
 None
 0.95A 4ndnC-3imlA:
50.9		 4ndnC-3imlA:
53.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NDN_C_SAMC405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 8 ALA A  42
GLU A  57
ASP A 122
LYS A 273
 None
 0.48A 4ndnD-3imlA:
52.5		 4ndnD-3imlA:
53.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 5 TYR A 361
GLY A  15
ASP A 167
VAL A 228
 None
 1.11A 4nkvD-3imlA:
undetectable		 4nkvD-3imlA:
19.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 7 HIS A  16
PRO A  17
ASP A 167
LYS A 169
ASP A 242
 None
 0.82A 4odjA-3imlA:
52.6		 4odjA-3imlA:
49.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 7 HIS A  16
PRO A  17
ASP A 167
LYS A 169
PHE A 234
 None
 0.27A 4odjA-3imlA:
52.6		 4odjA-3imlA:
49.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		3 / 3 PRO A 139
MET A 138
TYR A 255
 None
 0.80A 4qa0B-3imlA:
undetectable		 4qa0B-3imlA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		3 / 3 PRO A 139
MET A 138
TYR A 255
 None
 0.77A 4qa0A-3imlA:
undetectable		 4qa0A-3imlA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		3 / 3 PRO A 139
MET A 138
TYR A 255
 None
 0.90A 4qa2B-3imlA:
undetectable		 4qa2B-3imlA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 11 SER A 277
ALA A 281
ILE A 344
MET A 347
ILE A 354
 None
 1.19A 4xumB-3imlA:
undetectable		 4xumB-3imlA:
21.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		6 / 8 HIS A  16
PRO A  17
ASP A 167
LYS A 169
SER A 190
PHE A 234
 None
 0.24A 5a1iA-3imlA:
52.2		 5a1iA-3imlA:
53.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 8 HIS A  16
PRO A  17
LYS A 169
SER A 190
ASP A 242
 None
 0.83A 5a1iA-3imlA:
52.2		 5a1iA-3imlA:
53.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 7 HIS A  16
PRO A  17
ASP A 167
LYS A 169
PHE A 234
 None
 0.25A 5a1iA-3imlA:
52.2		 5a1iA-3imlA:
53.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 7 HIS A  16
PRO A  17
LYS A 169
ASP A 242
 None
 0.90A 5a1iA-3imlA:
52.2		 5a1iA-3imlA:
53.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 6 TYR A 355
ASP A 349
ILE A 344
TYR A  38
 None
 1.27A 5igyA-3imlA:
undetectable		 5igyA-3imlA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 6 TYR A 355
ASP A 349
ILE A 344
TYR A  38
 None
 1.30A 5ih0A-3imlA:
undetectable		 5ih0A-3imlA:
22.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 8 ALA A  42
GLU A  57
ASP A 122
LYS A 273
 None
 0.43A 5t8sA-3imlA:
56.8		 5t8sA-3imlA:
73.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		7 / 8 HIS A  16
PRO A  17
ASP A 167
LYS A 169
SER A 190
THR A 231
ASP A 242
 None
 0.92A 5t8sB-3imlA:
58.4		 5t8sB-3imlA:
73.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		7 / 8 HIS A  16
PRO A  17
ASP A 167
LYS A 169
SER A 190
THR A 231
PHE A 234
 None
 0.60A 5t8sB-3imlA:
58.4		 5t8sB-3imlA:
73.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FBN_B_SAMB401_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 7 ALA A  42
GLU A  57
ASP A 122
LYS A 273
 None
 0.49A 6fbnA-3imlA:
51.4		 6fbnA-3imlA:
53.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		6 / 8 HIS A  16
PRO A  17
ASP A 167
LYS A 169
SER A 190
PHE A 234
 None
 0.33A 6fbnB-3imlA:
49.6		 6fbnB-3imlA:
53.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 8 HIS A  16
PRO A  17
LYS A 169
SER A 190
ASP A 242
 None
 0.88A 6fbnB-3imlA:
49.6		 6fbnB-3imlA:
53.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		6 / 8 HIS A  16
PRO A  17
ASP A 167
LYS A 169
SER A 190
PHE A 234
 None
 0.24A 6fboA-3imlA:
52.6		 6fboA-3imlA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 8 HIS A  16
PRO A  17
LYS A 169
SER A 190
ASP A 242
 None
 0.85A 6fboA-3imlA:
52.6		 6fboA-3imlA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBP_B_ADNB404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		6 / 12 HIS A  16
PRO A  17
ASP A 167
LYS A 169
SER A 190
PHE A 234
 None
 0.20A 6fbpA-3imlA:
52.5
6fbpB-3imlA:
51.5		 6fbpA-3imlA:
10.78
6fbpB-3imlA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBP_B_ADNB404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 12 HIS A  16
PRO A  17
LYS A 169
SER A 190
ASP A 242
 None
 0.83A 6fbpA-3imlA:
52.5
6fbpB-3imlA:
51.5		 6fbpA-3imlA:
10.78
6fbpB-3imlA:
10.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		6 / 8 HIS A  16
PRO A  17
ASP A 167
LYS A 169
SER A 190
PHE A 234
 None
 0.31A 6fcbA-3imlA:
52.6		 6fcbA-3imlA:
53.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 8 HIS A  16
PRO A  17
LYS A 169
SER A 190
ASP A 242
 None
 0.93A 6fcbA-3imlA:
52.6		 6fcbA-3imlA:
53.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		6 / 8 HIS A  16
PRO A  17
ASP A 167
LYS A 169
SER A 190
PHE A 234
 None
 0.24A 6fcdA-3imlA:
52.3		 6fcdA-3imlA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 8 HIS A  16
PRO A  17
LYS A 169
SER A 190
ASP A 242
 None
 0.84A 6fcdA-3imlA:
52.3		 6fcdA-3imlA:
10.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		5 / 7 HIS A  16
PRO A  17
ASP A 167
LYS A 169
PHE A 234
 None
 0.25A 6g6rA-3imlA:
52.3		 6g6rA-3imlA:
53.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iml S-ADENOSYLMETHIONINE
SYNTHETASE
(Burkholderia
pseudomallei) 		4 / 7 HIS A  16
PRO A  17
LYS A 169
ASP A 242
 None
 0.91A 6g6rA-3imlA:
52.3		 6g6rA-3imlA:
53.86