SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3imm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 3imm PUTATIVE SECRETED
GLYCOSYLHYDROLASE
(Parabacteroides
distasonis) 		6 / 10 ALA A 131
LEU A 159
VAL A 157
ILE A 105
LEU A  74
ILE A 103
 None
 1.24A 3jw3A-3immA:
undetectable		 3jw3A-3immA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 3imm PUTATIVE SECRETED
GLYCOSYLHYDROLASE
(Parabacteroides
distasonis) 		5 / 9 ALA A 131
VAL A 157
ILE A 105
LEU A  74
ILE A 103
 None
 1.29A 3jw3B-3immA:
undetectable		 3jw3B-3immA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3imm PUTATIVE SECRETED
GLYCOSYLHYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A  74
TRP A  96
ILE A  61
GLY A 205
SER A  84
 None
 1.22A 3kk6B-3immA:
undetectable		 3kk6B-3immA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 3imm PUTATIVE SECRETED
GLYCOSYLHYDROLASE
(Parabacteroides
distasonis) 		4 / 8 ILE A 148
ILE A 219
LEU A  31
ILE A 201
 None
 0.90A 4dtaB-3immA:
undetectable		 4dtaB-3immA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3imm PUTATIVE SECRETED
GLYCOSYLHYDROLASE
(Parabacteroides
distasonis) 		4 / 6 ILE A 155
ILE A  97
LEU A 188
PHE A 192
 None
 0.91A 5vkqA-3immA:
undetectable
5vkqB-3immA:
undetectable		 5vkqA-3immA:
8.40
5vkqB-3immA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3imm PUTATIVE SECRETED
GLYCOSYLHYDROLASE
(Parabacteroides
distasonis) 		4 / 6 ILE A 155
ILE A  97
LEU A 188
PHE A 192
 None
 0.90A 5vkqB-3immA:
undetectable
5vkqC-3immA:
undetectable		 5vkqB-3immA:
8.40
5vkqC-3immA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3imm PUTATIVE SECRETED
GLYCOSYLHYDROLASE
(Parabacteroides
distasonis) 		4 / 6 ILE A 155
ILE A  97
LEU A 188
PHE A 192
 None
 0.89A 5vkqC-3immA:
undetectable
5vkqD-3immA:
undetectable		 5vkqC-3immA:
8.40
5vkqD-3immA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3imm PUTATIVE SECRETED
GLYCOSYLHYDROLASE
(Parabacteroides
distasonis) 		4 / 6 ILE A 155
ILE A  97
LEU A 188
PHE A 192
 None
 0.89A 5vkqA-3immA:
undetectable
5vkqD-3immA:
undetectable		 5vkqA-3immA:
8.40
5vkqD-3immA:
8.40