SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3io3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3io3 DEHA2D07832P
(Debaryomyces
hansenii) 		5 / 11 THR A 166
VAL A  29
GLY A  30
THR A  34
VAL A 266
 GOL  A 968 ( 4.3A)
ADP  A 590 (-4.1A)
ADP  A 590 (-3.0A)
None
None
 1.28A 2a1nA-3io3A:
undetectable		 2a1nA-3io3A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3io3 DEHA2D07832P
(Debaryomyces
hansenii) 		5 / 12 THR A 169
SER A  36
THR A  33
VAL A  23
GLY A  24
 None
None
ADP  A 590 (-3.7A)
None
None
 1.28A 2x2iC-3io3A:
undetectable		 2x2iC-3io3A:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NED_A_PFNA709_1
(LACTOTRANSFERRIN)		 3io3 DEHA2D07832P
(Debaryomyces
hansenii) 		4 / 6 VAL A  23
ASP A 162
ALA A  65
PHE A  66
 None
ADP  A 590 ( 4.7A)
None
None
 1.07A 4nedA-3io3A:
undetectable		 4nedA-3io3A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3io3 DEHA2D07832P
(Debaryomyces
hansenii) 		4 / 6 SER A 264
HIS A 305
PRO A   7
LEU A   9
 None
 1.48A 5dzka-3io3A:
undetectable
5dzko-3io3A:
undetectable		 5dzka-3io3A:
20.64
5dzko-3io3A:
3.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 3io3 DEHA2D07832P
(Debaryomyces
hansenii) 		4 / 6 PHE A 325
VAL A 237
LEU A   9
LEU A 329
 ADP  A 590 (-4.6A)
None
None
None
 0.90A 6e43A-3io3A:
undetectable		 6e43A-3io3A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 3io3 DEHA2D07832P
(Debaryomyces
hansenii) 		4 / 6 PHE A 325
VAL A 237
LEU A   9
LEU A 329
 ADP  A 590 (-4.6A)
None
None
None
 0.89A 6e43B-3io3A:
undetectable		 6e43B-3io3A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 3io3 DEHA2D07832P
(Debaryomyces
hansenii) 		4 / 6 PHE A 325
VAL A 237
LEU A   9
LEU A 329
 ADP  A 590 (-4.6A)
None
None
None
 0.88A 6e43C-3io3A:
undetectable		 6e43C-3io3A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_D_BEZD502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 3io3 DEHA2D07832P
(Debaryomyces
hansenii) 		4 / 6 PHE A 325
VAL A 237
LEU A   9
LEU A 329
 ADP  A 590 (-4.6A)
None
None
None
 0.91A 6e43D-3io3A:
undetectable		 6e43D-3io3A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 3io3 DEHA2D07832P
(Debaryomyces
hansenii) 		3 / 3 ALA A  74
PHE A  70
GLN A  68
 None
 0.80A 6eceA-3io3A:
3.3		 6eceA-3io3A:
22.75