SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ipr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDB_A_NPSA1591_1
(SERUM ALBUMIN)		 3ipr PTS SYSTEM, IIA
COMPONENT
(Enterococcus
faecalis) 		4 / 8 ILE A 122
HIS A 108
LEU A  62
PHE A  92
 None
 0.91A 2vdbA-3iprA:
undetectable		 2vdbA-3iprA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_A_AERA601_1
(CYP17A1 PROTEIN)		 3ipr PTS SYSTEM, IIA
COMPONENT
(Enterococcus
faecalis) 		5 / 9 ALA A   7
ILE A  91
ALA A  51
THR A  50
VAL A  79
 None
 1.26A 4r1zA-3iprA:
undetectable		 4r1zA-3iprA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)		 3ipr PTS SYSTEM, IIA
COMPONENT
(Enterococcus
faecalis) 		5 / 12 LEU A 103
ASN A  98
ALA A  16
ALA A  20
ILE A   6
 None
 1.11A 4x1kD-3iprA:
3.7		 4x1kD-3iprA:
16.40