SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3iq1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 3iq1 DPS FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 11 PHE A  30
ILE A  91
LEU A 147
LEU A 155
LEU A 151
 None
 1.02A 1dtlA-3iq1A:
undetectable		 1dtlA-3iq1A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)		 3iq1 DPS FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 114
GLY A 110
THR A  34
ILE A  56
LEU A 151
 None
 1.21A 4o5fA-3iq1A:
undetectable
4o5fB-3iq1A:
undetectable		 4o5fA-3iq1A:
18.88
4o5fB-3iq1A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 3iq1 DPS FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 151
LEU A 114
GLY A 110
THR A  34
ILE A  56
 None
 1.19A 4o5fA-3iq1A:
undetectable
4o5fB-3iq1A:
undetectable		 4o5fA-3iq1A:
18.88
4o5fB-3iq1A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QC6_B_KANB201_2
(BIFUNCTIONAL AAC/APH)		 3iq1 DPS FAMILY PROTEIN
(Vibrio
cholerae) 		3 / 3 LEU A 136
ASP A 139
TYR A 140
 None
 0.65A 4qc6B-3iq1A:
undetectable		 4qc6B-3iq1A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_A_PAUA302_0
(TYPE III
PANTOTHENATE KINASE)		 3iq1 DPS FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 114
GLY A 110
THR A  34
ILE A  56
LEU A 151
 None
 1.23A 5b8hA-3iq1A:
undetectable
5b8hB-3iq1A:
undetectable		 5b8hA-3iq1A:
22.22
5b8hB-3iq1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 3iq1 DPS FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 151
LEU A 114
GLY A 110
THR A  34
ILE A  56
 None
 1.19A 5b8hA-3iq1A:
undetectable
5b8hB-3iq1A:
undetectable		 5b8hA-3iq1A:
22.22
5b8hB-3iq1A:
22.22