SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ir8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 3ir8 LARGE STOKES SHIFT
FLUORESCENT PROTEIN
(Montipora
sp.
20) 		4 / 7 PHE A  79
TRP A  89
SER A 175
ARG A  91
 None
None
None
CRQ  A  64 ( 2.8A)
 1.28A 1rqpB-3ir8A:
undetectable		 1rqpB-3ir8A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3ir8 LARGE STOKES SHIFT
FLUORESCENT PROTEIN
(Montipora
sp.
20) 		3 / 3 SER A 175
GLY A 155
ARG A 193
 None
None
CRQ  A  64 ( 4.2A)
 0.67A 1t9wA-3ir8A:
undetectable		 1t9wA-3ir8A:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 3ir8 LARGE STOKES SHIFT
FLUORESCENT PROTEIN
(Montipora
sp.
20) 		4 / 7 PHE A 147
TYR A  78
TYR A 177
THR A 176
 None
 1.31A 2q6kA-3ir8A:
undetectable		 2q6kA-3ir8A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_B_ECNB1406_1
(CYTOCHROME P450 130)		 3ir8 LARGE STOKES SHIFT
FLUORESCENT PROTEIN
(Montipora
sp.
20) 		5 / 11 ASP A  74
PRO A  76
PRO A 186
MET A 185
THR A  69
 None
 1.40A 2uvnB-3ir8A:
undetectable		 2uvnB-3ir8A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1299_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 3ir8 LARGE STOKES SHIFT
FLUORESCENT PROTEIN
(Montipora
sp.
20) 		4 / 7 PHE A  79
TRP A  89
SER A 175
ARG A  91
 None
None
None
CRQ  A  64 ( 2.8A)
 1.30A 2v7uB-3ir8A:
undetectable		 2v7uB-3ir8A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ir8 LARGE STOKES SHIFT
FLUORESCENT PROTEIN
(Montipora
sp.
20) 		3 / 3 GLY A 151
PRO A 186
LEU A 153
 None
 0.63A 3hcpB-3ir8A:
undetectable		 3hcpB-3ir8A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 3ir8 LARGE STOKES SHIFT
FLUORESCENT PROTEIN
(Montipora
sp.
20) 		4 / 5 GLY A  36
ALA A 213
PHE A  68
GLU A 211
 None
None
None
CRQ  A  64 ( 3.3A)
 1.00A 4m93B-3ir8A:
undetectable
4m93C-3ir8A:
undetectable		 4m93B-3ir8A:
20.48
4m93C-3ir8A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 3ir8 LARGE STOKES SHIFT
FLUORESCENT PROTEIN
(Montipora
sp.
20) 		3 / 3 PRO A 186
MET A 185
TYR A  78
 None
 0.75A 4qa0B-3ir8A:
undetectable		 4qa0B-3ir8A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 3ir8 LARGE STOKES SHIFT
FLUORESCENT PROTEIN
(Montipora
sp.
20) 		3 / 3 PRO A 186
MET A 185
TYR A  78
 None
 0.76A 4qa0A-3ir8A:
undetectable		 4qa0A-3ir8A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 3ir8 LARGE STOKES SHIFT
FLUORESCENT PROTEIN
(Montipora
sp.
20) 		3 / 3 PRO A 186
MET A 185
TYR A  78
 None
 0.81A 4qa2B-3ir8A:
undetectable		 4qa2B-3ir8A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 3ir8 LARGE STOKES SHIFT
FLUORESCENT PROTEIN
(Montipora
sp.
20) 		4 / 5 GLN A  60
LEU A  61
SER A  58
ASP A 192
 None
CRQ  A  64 ( 4.7A)
None
None
 1.30A 4qtuD-3ir8A:
undetectable		 4qtuD-3ir8A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_BEZA401_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 3ir8 LARGE STOKES SHIFT
FLUORESCENT PROTEIN
(Montipora
sp.
20) 		5 / 9 LEU A  57
SER A  58
ILE A 120
VAL A  18
ILE A  56
 None
 1.30A 6ef6A-3ir8A:
undetectable		 6ef6A-3ir8A:
16.71