SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3irz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3irz URO-ADHERENCE FACTOR
A
(Staphylococcus
saprophyticus) 		5 / 12 PRO A 612
VAL A 635
TYR A 645
VAL A 620
LEU A 637
 None
 1.36A 1z9hA-3irzA:
undetectable		 1z9hA-3irzA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3irz URO-ADHERENCE FACTOR
A
(Staphylococcus
saprophyticus) 		5 / 12 PRO A 612
VAL A 635
TYR A 645
VAL A 620
LEU A 637
 None
 1.35A 1z9hB-3irzA:
undetectable		 1z9hB-3irzA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3irz URO-ADHERENCE FACTOR
A
(Staphylococcus
saprophyticus) 		5 / 12 PRO A 612
VAL A 635
TYR A 645
VAL A 620
LEU A 637
 None
 1.35A 1z9hC-3irzA:
undetectable		 1z9hC-3irzA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3irz URO-ADHERENCE FACTOR
A
(Staphylococcus
saprophyticus) 		5 / 12 PRO A 549
VAL A 550
THR A 634
ARG A 679
LYS A 579
 None
 0.96A 2v95A-3irzA:
undetectable		 2v95A-3irzA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_D_ASDD1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3irz URO-ADHERENCE FACTOR
A
(Staphylococcus
saprophyticus) 		4 / 7 ILE A 685
GLY A 661
LEU A 654
PHE A 587
 None
 1.03A 2vctD-3irzA:
undetectable		 2vctD-3irzA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3irz URO-ADHERENCE FACTOR
A
(Staphylococcus
saprophyticus) 		5 / 12 TYR A 556
ILE A 647
VAL A 597
ILE A 625
VAL A 580
 None
 1.24A 3fpjB-3irzA:
undetectable		 3fpjB-3irzA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_2
(FIV PROTEASE)		 3irz URO-ADHERENCE FACTOR
A
(Staphylococcus
saprophyticus) 		5 / 9 GLY A 805
ALA A 804
ASP A 803
ILE A 802
GLY A 743
 None
 0.99A 3ogpB-3irzA:
undetectable		 3ogpB-3irzA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_C_D16C301_1
(THYMIDYLATE SYNTHASE)		 3irz URO-ADHERENCE FACTOR
A
(Staphylococcus
saprophyticus) 		5 / 11 SER A 649
GLU A 594
ASP A 630
GLY A 631
PHE A 589
 None
 1.49A 4foxC-3irzA:
undetectable		 4foxC-3irzA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOS_A_4KOA201_1
(UNCHARACTERIZED
PROTEIN)		 3irz URO-ADHERENCE FACTOR
A
(Staphylococcus
saprophyticus) 		5 / 12 PRO A 729
GLY A 473
ILE A 476
TYR A 495
LEU A 734
 None
 1.28A 4kosA-3irzA:
undetectable		 4kosA-3irzA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 3irz URO-ADHERENCE FACTOR
A
(Staphylococcus
saprophyticus) 		5 / 12 PRO A 729
GLY A 473
ILE A 476
TYR A 495
LEU A 734
 None
 1.31A 4kotA-3irzA:
undetectable		 4kotA-3irzA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)		 3irz URO-ADHERENCE FACTOR
A
(Staphylococcus
saprophyticus) 		5 / 12 PRO A 729
GLY A 473
ILE A 476
TYR A 495
LEU A 734
 None
 1.32A 4kovA-3irzA:
undetectable		 4kovA-3irzA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOY_A_CSCA214_1
(UNCHARACTERIZED
PROTEIN)		 3irz URO-ADHERENCE FACTOR
A
(Staphylococcus
saprophyticus) 		5 / 11 PRO A 729
GLY A 473
ILE A 476
TYR A 495
LEU A 734
 None
 1.28A 4koyA-3irzA:
undetectable		 4koyA-3irzA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_1
(MDR769 HIV-1
PROTEASE)		 3irz URO-ADHERENCE FACTOR
A
(Staphylococcus
saprophyticus) 		5 / 11 GLY A 532
ALA A 531
ILE A 430
THR A 435
VAL A 402
 None
 1.08A 4l1aA-3irzA:
undetectable		 4l1aA-3irzA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 3irz URO-ADHERENCE FACTOR
A
(Staphylococcus
saprophyticus) 		3 / 3 ASN A 799
LEU A 726
PHE A 695
 None
 0.74A 5dsgA-3irzA:
undetectable		 5dsgA-3irzA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H4D_A_BBIA403_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 3irz URO-ADHERENCE FACTOR
A
(Staphylococcus
saprophyticus) 		4 / 6 PHE A 492
PHE A 506
GLU A 533
VAL A 530
 None
 1.39A 5h4dA-3irzA:
undetectable		 5h4dA-3irzA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 3irz URO-ADHERENCE FACTOR
A
(Staphylococcus
saprophyticus) 		5 / 11 GLN A 686
SER A 459
THR A 458
PRO A 651
LEU A 663
 None
 1.43A 5jh7B-3irzA:
undetectable		 5jh7B-3irzA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3irz URO-ADHERENCE FACTOR
A
(Staphylococcus
saprophyticus) 		4 / 6 ILE A 766
LEU A 806
PHE A 704
PHE A 783
 None
 0.87A 5vkqB-3irzA:
undetectable
5vkqC-3irzA:
undetectable		 5vkqB-3irzA:
13.06
5vkqC-3irzA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3irz URO-ADHERENCE FACTOR
A
(Staphylococcus
saprophyticus) 		4 / 6 ILE A 766
LEU A 806
PHE A 704
PHE A 783
 None
 0.87A 5vkqC-3irzA:
undetectable
5vkqD-3irzA:
undetectable		 5vkqC-3irzA:
13.06
5vkqD-3irzA:
13.06