SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3isa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		3 / 3 TRP A  19
ARG A 124
THR A  20
 None
 0.92A 1df7A-3isaA:
undetectable		 1df7A-3isaA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		5 / 9 GLY A 144
GLY A 140
LEU A 137
SER A 228
GLY A 136
 None
None
None
None
CL  A 256 (-3.4A)
 1.17A 1jhoA-3isaA:
2.7		 1jhoA-3isaA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		5 / 9 GLY A 144
GLY A 140
LEU A 137
SER A 228
GLY A 136
 None
None
None
None
CL  A 256 (-3.4A)
 1.20A 1jhrA-3isaA:
undetectable		 1jhrA-3isaA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		5 / 9 GLY A 144
GLY A 140
LEU A 137
SER A 228
GLY A 136
 None
None
None
None
CL  A 256 (-3.4A)
 1.21A 1jhyA-3isaA:
undetectable		 1jhyA-3isaA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		5 / 9 GLY A 144
GLY A 140
LEU A 137
SER A 228
GLY A 136
 None
None
None
None
CL  A 256 (-3.4A)
 1.18A 1l4nA-3isaA:
undetectable		 1l4nA-3isaA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		5 / 9 GLY A 144
GLY A 140
LEU A 137
SER A 228
GLY A 136
 None
None
None
None
CL  A 256 (-3.4A)
 1.16A 1l5kA-3isaA:
undetectable		 1l5kA-3isaA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		5 / 9 GLY A 144
GLY A 140
LEU A 137
SER A 228
GLY A 136
 None
None
None
None
CL  A 256 (-3.4A)
 1.16A 1l5lA-3isaA:
undetectable		 1l5lA-3isaA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		5 / 9 GLY A 144
GLY A 140
LEU A 137
SER A 228
GLY A 136
 None
None
None
None
CL  A 256 (-3.4A)
 1.16A 1l5mA-3isaA:
undetectable		 1l5mA-3isaA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		3 / 3 ARG A  94
ARG A  49
ARG A  87
 None
 0.80A 1l7fA-3isaA:
undetectable		 1l7fA-3isaA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		3 / 3 ARG A  94
ARG A  49
ARG A  87
 None
 0.83A 1l7hA-3isaA:
undetectable		 1l7hA-3isaA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRQ_A_STRA501_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		5 / 11 LEU A 117
GLU A  89
ILE A  88
LEU A  10
LEU A  36
 None
 1.32A 1mrqA-3isaA:
undetectable		 1mrqA-3isaA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		3 / 3 GLN A 184
HIS A 107
ARG A  62
 None
 0.86A 1zlqA-3isaA:
0.0		 1zlqA-3isaA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		5 / 12 GLU A  50
VAL A  52
TRP A  19
LEU A  55
PHE A  21
 None
 1.46A 2jj8C-3isaA:
undetectable		 2jj8C-3isaA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		6 / 12 ASP A 116
LEU A 117
GLY A 114
LEU A 143
LEU A  32
LEU A  36
 None
 1.14A 2nxeA-3isaA:
undetectable		 2nxeA-3isaA:
28.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		6 / 12 GLY A 136
ASP A 116
LEU A 117
GLY A 114
LEU A 143
LEU A  32
 CL  A 256 (-3.4A)
None
None
None
None
None
 1.28A 2nxeA-3isaA:
undetectable		 2nxeA-3isaA:
28.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		6 / 12 GLY A 136
LEU A 117
GLY A 114
GLY A 112
LEU A 143
LEU A  32
 CL  A 256 (-3.4A)
None
None
CL  A 257 ( 3.5A)
None
None
 1.46A 2nxeA-3isaA:
undetectable		 2nxeA-3isaA:
28.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		6 / 12 LEU A 117
GLY A 114
GLY A 112
LEU A 143
LEU A  32
LEU A  36
 None
None
CL  A 257 ( 3.5A)
None
None
None
 1.31A 2nxeA-3isaA:
undetectable		 2nxeA-3isaA:
28.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_A_PPFA3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		4 / 8 ARG A 214
HIS A 217
ASP A 150
ALA A  96
 None
 1.02A 2rk8A-3isaA:
undetectable		 2rk8A-3isaA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		6 / 12 LEU A 117
GLY A 114
GLY A 112
LEU A 143
LEU A  32
LEU A  36
 None
None
CL  A 257 ( 3.5A)
None
None
None
 1.27A 3cjtO-3isaA:
undetectable		 3cjtO-3isaA:
28.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		4 / 6 LEU A  23
SER A  24
LEU A   8
LEU A  36
 None
 0.94A 3f33A-3isaA:
undetectable		 3f33A-3isaA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		5 / 12 THR A  22
THR A  20
GLU A  13
LEU A 105
LEU A  40
 None
 1.38A 3gwxB-3isaA:
undetectable		 3gwxB-3isaA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		3 / 3 ASP A  45
ARG A  49
ARG A  87
 None
 0.69A 3k37A-3isaA:
undetectable		 3k37A-3isaA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		4 / 8 ARG A 214
ALA A 120
LEU A 117
ASP A 221
 None
 1.01A 3qj7A-3isaA:
undetectable
3qj7D-3isaA:
undetectable		 3qj7A-3isaA:
21.35
3qj7D-3isaA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		3 / 3 ARG A 227
ARG A 146
ASP A 219
 CL  A 258 (-4.3A)
None
None
 0.88A 3wipG-3isaA:
undetectable
3wipH-3isaA:
undetectable		 3wipG-3isaA:
18.31
3wipH-3isaA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		3 / 3 ARG A  14
ARG A  15
TRP A  19
 None
 1.48A 4cpzE-3isaA:
undetectable		 4cpzE-3isaA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		3 / 3 ARG A  14
ARG A  15
TRP A  19
 None
 1.49A 4cpzH-3isaA:
undetectable		 4cpzH-3isaA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLA_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		4 / 5 MET A 134
ARG A 146
ARG A 147
MET A  85
 None
 1.33A 4klaB-3isaA:
2.1		 4klaB-3isaA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		5 / 9 GLY A 144
GLY A 140
LEU A 137
SER A 228
GLY A 136
 None
None
None
None
CL  A 256 (-3.4A)
 1.24A 4kqiA-3isaA:
undetectable		 4kqiA-3isaA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_ADNA2414_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		4 / 6 GLU A  78
PHE A 234
ARG A 239
TYR A  73
 None
 1.43A 4uciA-3isaA:
undetectable		 4uciA-3isaA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		4 / 7 GLU A  78
PHE A 234
ARG A 239
TYR A  73
 None
 1.44A 4uciB-3isaA:
undetectable		 4uciB-3isaA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_B_CHDB102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		5 / 11 LEU A  36
LEU A  40
LEU A  23
ALA A 113
LEU A 117
 None
None
None
CL  A 257 (-3.8A)
None
 1.10A 4wg0B-3isaA:
undetectable
4wg0C-3isaA:
undetectable
4wg0D-3isaA:
undetectable		 4wg0B-3isaA:
6.47
4wg0C-3isaA:
6.47
4wg0D-3isaA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_D_CHDD102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		5 / 11 LEU A  36
LEU A  40
LEU A  23
ALA A 113
LEU A 117
 None
None
None
CL  A 257 (-3.8A)
None
 1.10A 4wg0D-3isaA:
undetectable
4wg0E-3isaA:
undetectable
4wg0F-3isaA:
undetectable		 4wg0D-3isaA:
6.47
4wg0E-3isaA:
6.47
4wg0F-3isaA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_F_CHDF103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		5 / 11 LEU A  36
LEU A  40
LEU A  23
ALA A 113
LEU A 117
 None
None
None
CL  A 257 (-3.8A)
None
 1.13A 4wg0F-3isaA:
undetectable
4wg0G-3isaA:
undetectable
4wg0H-3isaA:
undetectable		 4wg0F-3isaA:
6.47
4wg0G-3isaA:
6.47
4wg0H-3isaA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_H_CHDH103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		5 / 11 LEU A  36
LEU A  40
LEU A  23
ALA A 113
LEU A 117
 None
None
None
CL  A 257 (-3.8A)
None
 1.13A 4wg0H-3isaA:
undetectable
4wg0I-3isaA:
undetectable
4wg0J-3isaA:
undetectable		 4wg0H-3isaA:
6.47
4wg0I-3isaA:
6.47
4wg0J-3isaA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		5 / 11 ALA A 113
LEU A 117
LEU A  23
LEU A  36
LEU A  40
 CL  A 257 (-3.8A)
None
None
None
None
 1.11A 4wg0G-3isaA:
undetectable
4wg0H-3isaA:
undetectable
4wg0I-3isaA:
undetectable		 4wg0G-3isaA:
6.47
4wg0H-3isaA:
6.47
4wg0I-3isaA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		5 / 11 LEU A  36
LEU A  40
LEU A  23
ALA A 113
LEU A 117
 None
None
None
CL  A 257 (-3.8A)
None
 1.16A 4wg0J-3isaA:
undetectable
4wg0K-3isaA:
undetectable
4wg0L-3isaA:
undetectable		 4wg0J-3isaA:
6.47
4wg0K-3isaA:
6.47
4wg0L-3isaA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		5 / 11 ALA A 113
LEU A 117
LEU A  23
LEU A  36
LEU A  40
 CL  A 257 (-3.8A)
None
None
None
None
 1.14A 4wg0I-3isaA:
undetectable
4wg0J-3isaA:
undetectable
4wg0K-3isaA:
undetectable		 4wg0I-3isaA:
6.47
4wg0J-3isaA:
6.47
4wg0K-3isaA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		5 / 11 ALA A 113
LEU A 117
LEU A  23
LEU A  36
LEU A  40
 CL  A 257 (-3.8A)
None
None
None
None
 1.13A 4wg0K-3isaA:
undetectable
4wg0L-3isaA:
undetectable
4wg0M-3isaA:
undetectable		 4wg0K-3isaA:
6.47
4wg0L-3isaA:
6.47
4wg0M-3isaA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)		 3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE
(Bordetella
parapertussis) 		4 / 7 GLY A 114
PHE A  64
LEU A  23
GLU A  89
 None
 0.79A 5izfA-3isaA:
undetectable		 5izfA-3isaA:
21.79