SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ist'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_A_GBNA502_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 3ist GLUTAMATE RACEMASE
(Listeria
monocytogenes) 		4 / 8 GLY A 207
THR A 210
ALA A 211
VAL A  30
 None
 0.84A 2a1hA-3istA:
undetectable
2a1hB-3istA:
undetectable		 2a1hA-3istA:
23.02
2a1hB-3istA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_B_GBNB501_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 3ist GLUTAMATE RACEMASE
(Listeria
monocytogenes) 		4 / 8 VAL A  30
GLY A 207
THR A 210
ALA A 211
 None
 0.87A 2a1hA-3istA:
undetectable
2a1hB-3istA:
undetectable		 2a1hA-3istA:
23.02
2a1hB-3istA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA501_1
(CYTOCHROME P450 2C8)		 3ist GLUTAMATE RACEMASE
(Listeria
monocytogenes) 		5 / 11 SER A 206
ILE A  95
ALA A 128
VAL A 113
ILE A 111
 None
 1.09A 2nnhA-3istA:
undetectable		 2nnhA-3istA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3ist GLUTAMATE RACEMASE
(Listeria
monocytogenes) 		4 / 8 GLU A  28
LEU A 218
VAL A  69
ALA A   4
 None
 0.99A 3ax9A-3istA:
undetectable		 3ax9A-3istA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 3ist GLUTAMATE RACEMASE
(Listeria
monocytogenes) 		4 / 8 ILE A 180
LEU A 181
THR A 106
GLY A  98
 None
 0.81A 3dcjB-3istA:
3.8		 3dcjB-3istA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_B_SAMB1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3ist GLUTAMATE RACEMASE
(Listeria
monocytogenes) 		5 / 12 GLY A  13
TYR A  32
SER A  10
LEU A 181
GLY A 115
 None
None
SIN  A 267 (-2.5A)
None
None
 1.22A 4blvB-3istA:
undetectable		 4blvB-3istA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_B_CLQB303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3ist GLUTAMATE RACEMASE
(Listeria
monocytogenes) 		5 / 11 HIS A 233
PHE A 235
PHE A 244
GLY A  14
GLY A  13
 None
 1.30A 4fglA-3istA:
2.4
4fglB-3istA:
2.4		 4fglA-3istA:
24.22
4fglB-3istA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3ist GLUTAMATE RACEMASE
(Listeria
monocytogenes) 		4 / 8 GLY A  34
GLY A  13
GLU A 151
TYR A  41
 None
 0.75A 4fgzA-3istA:
undetectable		 4fgzA-3istA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3ist GLUTAMATE RACEMASE
(Listeria
monocytogenes) 		4 / 8 GLY A  34
GLY A  13
GLU A 151
TYR A  41
 None
 0.76A 4fgzB-3istA:
undetectable		 4fgzB-3istA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8W_G_MTXG301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 3ist GLUTAMATE RACEMASE
(Listeria
monocytogenes) 		5 / 9 PHE A 196
GLY A 182
CYH A 183
LEU A 181
HIS A 185
 None
None
SIN  A 267 (-3.1A)
None
SIN  A 267 ( 4.7A)
 1.48A 4l8wG-3istA:
2.3		 4l8wG-3istA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3ist GLUTAMATE RACEMASE
(Listeria
monocytogenes) 		4 / 5 ALA A  37
GLY A 239
ASP A  62
ASP A  35
 None
 0.76A 4n48A-3istA:
undetectable		 4n48A-3istA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_ACTC202_0
(RETINOL-BINDING
PROTEIN 2)		 3ist GLUTAMATE RACEMASE
(Listeria
monocytogenes) 		4 / 6 TYR A  32
GLU A 151
THR A  36
LEU A  15
 None
 1.43A 4qzuC-3istA:
undetectable		 4qzuC-3istA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HUA_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 3ist GLUTAMATE RACEMASE
(Listeria
monocytogenes) 		5 / 11 TYR A  41
ASP A  35
ARG A  38
ILE A  70
LEU A  33
 None
 1.15A 5huaA-3istA:
undetectable		 5huaA-3istA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)		 3ist GLUTAMATE RACEMASE
(Listeria
monocytogenes) 		4 / 8 ALA A   4
VAL A  94
TYR A  32
HIS A 233
 None
 0.96A 5nu7A-3istA:
undetectable		 5nu7A-3istA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Z_A_BHAA201_0
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3ist GLUTAMATE RACEMASE
(Listeria
monocytogenes) 		5 / 6 LEU A  15
ARG A  19
VAL A  18
LEU A  22
VAL A  30
 None
 1.35A 5x7zA-3istA:
undetectable		 5x7zA-3istA:
21.80