SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3it4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C4D_A_DVAA6_0 (GRAMICIDIN A)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	3 / 3	ALA A 24 VAL A 147 TRP A 113	None	0.91A	1c4dA-3it4A: undetectable 1c4dB-3it4A: undetectable	1c4dA-3it4A: 9.65 1c4dB-3it4A: 9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C4D_B_DVAB6_0 (GRAMICIDIN A)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	3 / 3	TRP A 113 ALA A 24 VAL A 147	None	0.84A	1c4dA-3it4A: undetectable 1c4dB-3it4A: undetectable	1c4dA-3it4A: 9.65 1c4dB-3it4A: 9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C4D_B_DVAB6_0 (GRAMICIDIN A)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	3 / 3	TRP A 113 ALA A 25 VAL A 147	None	0.90A	1c4dA-3it4A: undetectable 1c4dB-3it4A: undetectable	1c4dA-3it4A: 9.65 1c4dB-3it4A: 9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GMK_A_DVAA6_0 (GRAMICIDIN A)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	3 / 3	ALA B 349 VAL B 344 TRP B 323	None	0.92A	1gmkA-3it4B: undetectable 1gmkB-3it4B: undetectable	1gmkA-3it4B: 8.93 1gmkB-3it4B: 8.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GMK_C_DVAC6_0 (GRAMICIDIN A)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	3 / 3	ALA B 349 VAL B 344 TRP B 323	None	1.01A	1gmkC-3it4B: undetectable 1gmkD-3it4B: undetectable	1gmkC-3it4B: 8.93 1gmkD-3it4B: 8.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HSH_A_MK1A401_2 (HIV-II PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	5 / 9	ALA A 40 VAL A 16 GLY A 157 PRO A 171 ILE A 164	None	0.94A	1hshB-3it4A: undetectable	1hshB-3it4A: 19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JLB_A_NVPA999_1 (HIV-1 RT A-CHAIN)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	5 / 8	LEU B 245 VAL A 184 CYH B 268 GLY A 185 LEU B 260	None	1.24A	1jlbA-3it4B: undetectable	1jlbA-3it4B: 15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_B_FUAB703_2 (CHLORAMPHENICOL ACETYLTRANSFERASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	3 / 3	VAL A 42 ALA A 24 HIS A 151	None	0.73A	1q23C-3it4A: undetectable	1q23C-3it4A: 19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_G_FUAG708_2 (CHLORAMPHENICOL ACETYLTRANSFERASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	3 / 3	VAL A 42 ALA A 24 HIS A 151	None	0.70A	1q23H-3it4A: undetectable	1q23H-3it4A: 19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SDT_B_MK1B902_2 (PROTEASE RETROPEPSIN)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	5 / 12	ASP B 241 ILE A 130 GLY A 128 PRO A 64 VAL A 65	None	0.97A	1sdtB-3it4B: undetectable	1sdtB-3it4B: 19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T3R_A_017A1200_1 (PROTEASE RETROPEPSIN)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	5 / 10	LEU A 66 GLY A 92 ASP A 98 ILE A 130 VAL A 65	None	0.86A	1t3rA-3it4A: undetectable	1t3rA-3it4A: 16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YMX_A_CFXA1001_2 (BETA-LACTAMASE CTX-M-9)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	4 / 5	CYH B 352 PRO B 359 THR B 374 SER B 343	None	1.10A	1ymxA-3it4B: undetectable	1ymxA-3it4B: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXQ_A_IMNA2001_1 (SERUM ALBUMIN)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	5 / 10	ALA B 211 ALA A 51 LEU A 72 LEU A 77 LEU B 260	None None GOL A 500 (-4.9A) None None	1.18A	2bxqA-3it4B: undetectable	2bxqA-3it4B: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HZQ_A_STRA300_1 (APOLIPOPROTEIN D)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	4 / 7	THR A 68 ALA A 87 ASN B 240 LEU A 134	None	1.07A	2hzqA-3it4A: undetectable	2hzqA-3it4A: 21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IEN_B_017B402_1 (PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	6 / 12	LEU A 66 GLY A 92 ASP A 98 GLY A 131 ILE A 130 VAL A 65	None	1.47A	2ienA-3it4A: undetectable	2ienA-3it4A: 16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IEO_A_017A402_2 (PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	5 / 12	LEU A 66 GLY A 92 ASP A 98 ILE A 130 VAL A 65	None	0.76A	2ieoB-3it4A: undetectable	2ieoB-3it4A: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NMZ_B_ROCB401_2 (PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	3 / 3	ARG A 133 VAL A 124 THR A 102	None	0.83A	2nmzA-3it4A: undetectable	2nmzA-3it4A: 17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NNK_A_ROCA401_2 (PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	3 / 3	ARG A 133 VAL A 124 THR A 102	None	0.84A	2nnkA-3it4A: undetectable	2nnkA-3it4A: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NNK_A_ROCA401_3 (PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	5 / 12	LEU A 66 GLY A 92 ASP A 98 ILE A 130 VAL A 65	None	0.73A	2nnkB-3it4A: undetectable	2nnkB-3it4A: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2O4P_A_TPVA300_1 (PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	5 / 11	ASP B 241 ILE A 130 GLY A 128 PRO A 64 VAL A 65	None	1.00A	2o4pA-3it4B: undetectable	2o4pA-3it4B: 19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OPX_A_DXCA1003_0 (ALDEHYDE DEHYDROGENASE A)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	4 / 5	ILE B 335 LEU B 337 ASP B 376 ALA B 299	None	0.93A	2opxA-3it4B: undetectable	2opxA-3it4B: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VH3_B_DAHB2_1 (RANASMURFIN)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	4 / 8	ALA B 209 GLY A 46 SER B 251 ALA B 250	None	0.81A	2vh3B-3it4B: undetectable	2vh3B-3it4B: 21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X1L_A_ADNA601_1 (METHIONYL-TRNA SYNTHETASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	5 / 11	ALA A 87 ALA A 62 GLY A 92 GLY A 131 ILE A 130	None	1.08A	2x1lA-3it4A: undetectable	2x1lA-3it4A: 19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XAD_E_GCSE710_1 (N-ACYL GLM PEUDO-TEICOPLANIN DEACETYLASE TEICOPLANIN)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	4 / 8	HIS A 178 ASP B 259 HIS A 179 ASP A 180	None	1.12A	2xadA-3it4A: undetectable	2xadA-3it4A: 22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XAD_F_GCSF710_1 (N-ACYL GLM PEUDO-TEICOPLANIN DEACETYLASE TEICOPLANIN)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	4 / 8	HIS A 178 ASP B 259 HIS A 179 ASP A 180	None	1.10A	2xadB-3it4A: undetectable	2xadB-3it4A: 22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XAD_G_GCSG710_1 (N-ACYL GLM PEUDO-TEICOPLANIN DEACETYLASE TEICOPLANIN)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	4 / 8	HIS A 178 ASP B 259 HIS A 179 ASP A 180	None	1.11A	2xadC-3it4A: undetectable	2xadC-3it4A: 22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BVB_B_017B401_2 (PROTEASE (RETROPEPSIN))	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	6 / 12	LEU A 66 GLY A 92 ASP A 98 GLY A 131 ILE A 130 VAL A 65	None	1.41A	3bvbB-3it4A: undetectable	3bvbB-3it4A: 16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D1X_A_ROCA201_2 (HIV-1 PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	5 / 12	LEU A 66 GLY A 92 ASP A 98 ILE A 130 VAL A 65	None	0.83A	3d1xB-3it4A: undetectable	3d1xB-3it4A: 17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D1Z_B_017B201_1 (HIV-1 PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	5 / 12	ASP B 241 ILE A 130 GLY A 128 PRO A 64 VAL A 65	None	1.00A	3d1zA-3it4B: undetectable	3d1zA-3it4B: 18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D20_A_017A201_2 (HIV-1 PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	5 / 12	LEU A 66 GLY A 92 ASP A 98 ILE A 130 VAL A 65	None	0.78A	3d20B-3it4A: undetectable	3d20B-3it4A: 18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EKY_A_DR7A100_2 (PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	5 / 9	ASP B 241 ILE A 130 GLY A 128 PRO A 64 VAL A 65	None	0.99A	3ekyB-3it4B: undetectable	3ekyB-3it4B: 18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EM3_B_478B200_2 (PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	5 / 10	ASP B 241 ILE A 130 GLY A 128 PRO A 64 VAL A 65	None	1.00A	3em3B-3it4B: undetectable	3em3B-3it4B: 19.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3IT4_C_BEZC503_0 (ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	4 / 4	ARG A 9 GLN A 14 LEU A 154 HIS A 177	None	0.37A	3it4C-3it4A: 38.0	3it4C-3it4A: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JW2_A_017A401_1 (GAG-POL POLYPROTEIN)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	6 / 12	LEU A 66 GLY A 92 ASP A 98 GLY A 131 ILE A 130 VAL A 65	None	1.46A	3jw2A-3it4A: undetectable	3jw2A-3it4A: 16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JW2_A_017A401_2 (GAG-POL POLYPROTEIN)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	6 / 12	LEU A 66 GLY A 92 ASP A 98 GLY A 131 ILE A 130 VAL A 65	None	1.48A	3jw2B-3it4A: undetectable	3jw2B-3it4A: 16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K4V_B_ROCB201_1 (HIV-1 PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	6 / 12	LEU A 66 GLY A 92 ASP A 98 GLY A 131 ILE A 130 VAL A 65	None	1.50A	3k4vA-3it4A: undetectable	3k4vA-3it4A: 16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K4V_B_ROCB201_2 (HIV-1 PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	3 / 3	ARG A 133 VAL A 124 THR A 102	None	0.83A	3k4vA-3it4A: undetectable	3k4vA-3it4A: 16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K4V_B_ROCB201_3 (HIV-1 PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	6 / 12	LEU A 66 GLY A 92 ASP A 98 GLY A 131 ILE A 130 VAL A 65	None	1.45A	3k4vB-3it4A: undetectable	3k4vB-3it4A: 16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KW4_A_TICA600_1 (CYTOCHROME P450 2B4)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	5 / 11	ILE B 306 ILE B 335 ALA B 329 ILE B 342 VAL B 375	None	0.97A	3kw4A-3it4B: undetectable	3kw4A-3it4B: 18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LZV_A_017A200_2 (HIV-1 PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	5 / 11	ASP B 241 ILE A 130 GLY A 128 PRO A 64 VAL A 65	None	0.92A	3lzvB-3it4B: undetectable	3lzvB-3it4B: 19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDT_A_ROCA101_2 (PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	3 / 3	ARG A 133 VAL A 124 THR A 102	None	0.64A	3ndtA-3it4A: undetectable	3ndtA-3it4A: 16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDT_A_ROCA101_3 (PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	6 / 12	LEU A 66 GLY A 92 ASP A 98 GLY A 131 ILE A 130 VAL A 65	None	1.38A	3ndtB-3it4A: undetectable	3ndtB-3it4A: 16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDT_D_ROCD100_1 (PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	5 / 12	LEU A 66 GLY A 92 ASP A 98 ILE A 130 VAL A 65	None	0.85A	3ndtC-3it4A: undetectable	3ndtC-3it4A: 16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDU_D_ROCD100_1 (PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	5 / 12	LEU A 66 GLY A 92 ASP A 98 ILE A 130 VAL A 65	None	0.79A	3nduC-3it4A: undetectable	3nduC-3it4A: 16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NUJ_B_478B401_1 (PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	5 / 10	ASP B 241 ILE A 130 GLY A 128 PRO A 64 VAL A 65	None	0.93A	3nujA-3it4B: undetectable	3nujA-3it4B: 17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NUO_B_478B478_1 (PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	5 / 9	ASP B 241 ILE A 130 GLY A 128 PRO A 64 VAL A 65	None	0.96A	3nuoA-3it4B: undetectable	3nuoA-3it4B: 19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3O14_A_NIOA300_1 (ANTI-ECFSIGMA FACTOR, CHRR)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	4 / 7	ALA A 40 VAL A 16 VAL A 42 LEU A 82	None	0.80A	3o14A-3it4A: undetectable	3o14A-3it4A: 27.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OXX_A_DR7A100_2 (HIV-1 PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	5 / 11	ASP B 241 ILE A 130 GLY A 128 PRO A 64 VAL A 65	None	0.97A	3oxxB-3it4B: undetectable	3oxxB-3it4B: 19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OXX_C_DR7C100_1 (HIV-1 PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	5 / 12	ASP B 241 ILE A 130 GLY A 128 PRO A 64 VAL A 65	None	0.94A	3oxxC-3it4B: undetectable	3oxxC-3it4B: 19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PWM_B_017B402_1 (PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	5 / 12	LEU A 66 GLY A 92 ASP A 98 ILE A 130 VAL A 65	None	0.85A	3pwmA-3it4A: undetectable	3pwmA-3it4A: 16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PWR_A_ROCA401_2 (PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	3 / 3	ARG A 133 VAL A 124 THR A 102	None	0.79A	3pwrA-3it4A: undetectable	3pwrA-3it4A: 16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R75_A_BEZA701_0 (ANTHRANILATE/PARA-AM INOBENZOATE SYNTHASES COMPONENT I)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis; Mycobacterium tuberculosis)	5 / 12	GLU B 280 GLY A 128 THR A 127 SER B 238 LYS B 200	None	1.27A	3r75A-3it4B: undetectable	3r75A-3it4B: 16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R75_B_BEZB701_0 (ANTHRANILATE/PARA-AM INOBENZOATE SYNTHASES COMPONENT I)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis; Mycobacterium tuberculosis)	5 / 12	GLU B 280 GLY A 128 THR A 127 SER B 238 LYS B 200	None	1.24A	3r75B-3it4B: undetectable	3r75B-3it4B: 16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TKG_B_ROCB801_2 (PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	5 / 12	LEU A 66 GLY A 92 ASP A 98 ILE A 130 VAL A 65	None	0.81A	3tkgB-3it4A: undetectable	3tkgB-3it4A: 16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TKW_B_017B401_2 (PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	6 / 12	LEU A 66 GLY A 92 ASP A 98 GLY A 131 ILE A 130 VAL A 65	None	1.38A	3tkwB-3it4A: undetectable	3tkwB-3it4A: 16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TL9_A_ROCA401_1 (PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	6 / 12	LEU A 66 GLY A 92 ASP A 98 GLY A 131 ILE A 130 VAL A 65	None	1.45A	3tl9A-3it4A: undetectable	3tl9A-3it4A: 16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TL9_A_ROCA401_2 (PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	3 / 3	ARG A 133 VAL A 124 THR A 102	None	0.87A	3tl9A-3it4A: undetectable	3tl9A-3it4A: 16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DQB_B_017B101_2 (ASPARTYL PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	5 / 10	LEU A 66 GLY A 92 ASP A 98 ILE A 130 VAL A 65	None	0.85A	4dqbB-3it4A: undetectable	4dqbB-3it4A: 16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DQE_B_017B101_2 (ASPARTYL PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	5 / 10	LEU A 66 GLY A 92 ASP A 98 ILE A 130 VAL A 65	None	0.82A	4dqeB-3it4A: undetectable	4dqeB-3it4A: 16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DQH_B_017B101_2 (WILD-TYPE HIV-1 PROTEASE DIMER)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	5 / 10	LEU A 66 GLY A 92 ASP A 98 ILE A 130 VAL A 65	None	0.85A	4dqhB-3it4A: undetectable	4dqhB-3it4A: 16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4H1N_A_CGEA505_1 (CYTOCHROME P450 2B4)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	5 / 11	ILE B 306 ILE B 335 ALA B 329 ILE B 342 VAL B 375	None	0.92A	4h1nA-3it4B: undetectable	4h1nA-3it4B: 19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J7X_F_SASF805_1 (SEPIAPTERIN REDUCTASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	5 / 12	CYH B 268 PHE B 228 ASP B 241 MET B 201 GLY A 190	None	1.36A	4j7xF-3it4B: undetectable	4j7xF-3it4B: 26.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JEC_B_478B401_1 (HIV-1 PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	6 / 12	LEU A 66 GLY A 92 ASP A 98 GLY A 131 ILE A 130 VAL A 65	None	1.43A	4jecA-3it4A: undetectable	4jecA-3it4A: 16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOE_H_TR6H101_1 (DNA TOPOISOMERASE 4 SUBUNIT A DNA TOPOISOMERASE 4 SUBUNIT B E-SITE DNA4)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	4 / 7	ARG B 285 ASP B 278 GLY B 281 GLU B 398	None	0.83A	4koeA-3it4B: undetectable 4koeB-3it4B: undetectable 4koeD-3it4B: undetectable	4koeA-3it4B: 19.26 4koeB-3it4B: 19.26 4koeD-3it4B: 20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PD9_A_ADNA501_1 (NUPC FAMILY PROTEIN)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	5 / 12	GLY B 348 ALA B 349 VAL B 364 LEU B 366 ILE B 373	None	1.15A	4pd9A-3it4B: undetectable	4pd9A-3it4B: 19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q1W_A_017A104_1 (ASPARTYL PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	5 / 9	LEU A 66 GLY A 92 ASP A 98 ILE A 130 VAL A 65	None	1.02A	4q1wA-3it4A: undetectable	4q1wA-3it4A: 15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWD_A_377A402_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	5 / 9	ALA B 215 ALA B 211 ALA B 209 SER B 247 ALA B 219	None	1.34A	4twdA-3it4B: undetectable 4twdB-3it4B: undetectable 4twdC-3it4B: undetectable 4twdD-3it4B: undetectable 4twdE-3it4B: undetectable	4twdA-3it4B: 17.83 4twdB-3it4B: 17.83 4twdC-3it4B: 17.83 4twdD-3it4B: 17.83 4twdE-3it4B: 17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YVG_A_SAMA301_0 (TRNA (GUANINE-N(1)-)-METH YLTRANSFERASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis; Mycobacterium tuberculosis)	5 / 12	GLY A 15 GLY A 157 LEU B 205 GLY A 186 GLY A 185	None	1.11A	4yvgA-3it4A: undetectable	4yvgA-3it4A: 23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z53_H_TR6H101_1 (DNA TOPOISOMERASE 4 SUBUNIT B,DNA TOPOISOMERASE 4 SUBUNIT A E-SITE DNA)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	4 / 7	ARG B 285 ASP B 278 GLY B 281 GLU B 398	None	0.81A	4z53A-3it4B: undetectable 4z53B-3it4B: undetectable	4z53A-3it4B: 15.66 4z53B-3it4B: 15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BTG_F_LFXF101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCAT GACC)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	5 / 7	ARG B 285 ALA B 369 ASP B 278 GLY B 281 GLU B 398	None	1.43A	5btgA-3it4B: undetectable 5btgC-3it4B: undetectable 5btgD-3it4B: undetectable	5btgA-3it4B: 20.20 5btgC-3it4B: 20.20 5btgD-3it4B: 22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5C0O_G_SAMG301_0 (TRNA (ADENINE(58)-N(1))-M ETHYLTRANSFERASE TRMI)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis; Mycobacterium tuberculosis)	5 / 12	ALA A 18 GLY A 186 GLY A 15 GLY A 157 LEU B 205	None	0.97A	5c0oG-3it4A: undetectable	5c0oG-3it4A: 22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KR0_A_478A101_2 (PROTEASE E35D-APV)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN (Mycobacterium tuberculosis)	6 / 9	LEU A 66 GLY A 92 ASP A 98 GLY A 131 ILE A 130 VAL A 65	None	1.50A	5kr0B-3it4A: undetectable	5kr0B-3it4A: 16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ND2_B_TA1B601_1 (TUBULIN BETA-2B CHAIN)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	5 / 12	VAL B 364 GLU B 363 LEU B 327 ALA B 361 ARG B 325	None None None None ACT B 601 (-4.0A)	1.29A	5nd2B-3it4B: undetectable	5nd2B-3it4B: 18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5SYF_B_TA1B502_1 (TUBULIN BETA CHAIN)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis)	5 / 12	VAL B 243 LEU A 10 ASP B 269 ARG A 12 GLN A 14	None	1.32A	5syfB-3it4B: undetectable	5syfB-3it4B: 20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WYQ_A_SAMA401_0 (TRNA (GUANINE-N(1)-)-METH YLTRANSFERASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis; Mycobacterium tuberculosis)	5 / 12	GLY A 15 GLY A 157 LEU B 205 GLY A 186 GLY A 185	None	1.12A	5wyqA-3it4A: undetectable	5wyqA-3it4A: 23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DIL_B_TPVB201_0 (HIV-1 PROTEASE)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis; Mycobacterium tuberculosis)	5 / 12	ASP B 241 ILE A 130 GLY A 128 PRO A 64 VAL A 65	None	0.98A	6dilA-3it4B: undetectable	6dilA-3it4B: 19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6I5Z_D_SAMD401_0 (O-METHYLTRANSFERASE 1)	3it4	ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN (Mycobacterium tuberculosis; Mycobacterium tuberculosis)	5 / 11	SER B 248 GLY A 15 GLY A 185 LEU B 271 VAL B 267	None	1.21A	6i5zD-3it4B: undetectable	6i5zD-3it4B: 18.86

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1C4D_A_DVAA6_0","GRAMICIDIN A","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",3,"ALA A  24;VAL A 147;TRP A 113","None","0.91A","1c4dA-3it4A:undetectable;1c4dB-3it4A:undetectable","1c4dA-3it4A:9.65;1c4dB-3it4A:9.65"],["1C4D_B_DVAB6_0","GRAMICIDIN A","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",3,"TRP A 113;ALA A  24;VAL A 147","None","0.84A","1c4dA-3it4A:undetectable;1c4dB-3it4A:undetectable","1c4dA-3it4A:9.65;1c4dB-3it4A:9.65"],["1C4D_B_DVAB6_0","GRAMICIDIN A","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",3,"TRP A 113;ALA A  25;VAL A 147","None","0.90A","1c4dA-3it4A:undetectable;1c4dB-3it4A:undetectable","1c4dA-3it4A:9.65;1c4dB-3it4A:9.65"],["1GMK_A_DVAA6_0","GRAMICIDIN A","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",3,"ALA B 349;VAL B 344;TRP B 323","None","0.92A","1gmkA-3it4B:undetectable;1gmkB-3it4B:undetectable","1gmkA-3it4B:8.93;1gmkB-3it4B:8.93"],["1GMK_C_DVAC6_0","GRAMICIDIN A","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",3,"ALA B 349;VAL B 344;TRP B 323","None","1.01A","1gmkC-3it4B:undetectable;1gmkD-3it4B:undetectable","1gmkC-3it4B:8.93;1gmkD-3it4B:8.93"],["1HSH_A_MK1A401_2","HIV-II PROTEASE;HIV-II PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",5,"ALA A  40;VAL A  16;GLY A 157;PRO A 171;ILE A 164","None","0.94A","1hshB-3it4A:undetectable","1hshB-3it4A:19.80"],["1JLB_A_NVPA999_1","HIV-1 RT A-CHAIN","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",5,"LEU B 245;VAL A 184;CYH B 268;GLY A 185;LEU B 260","None","1.24A","1jlbA-3it4B:undetectable","1jlbA-3it4B:15.37"],["1Q23_B_FUAB703_2","CHLORAMPHENICOL ACETYLTRANSFERASE;CHLORAMPHENICOL ACETYLTRANSFERASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",3,"VAL A  42;ALA A  24;HIS A 151","None","0.73A","1q23C-3it4A:undetectable","1q23C-3it4A:19.92"],["1Q23_G_FUAG708_2","CHLORAMPHENICOL ACETYLTRANSFERASE;CHLORAMPHENICOL ACETYLTRANSFERASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",3,"VAL A  42;ALA A  24;HIS A 151","None","0.70A","1q23H-3it4A:undetectable","1q23H-3it4A:19.92"],["1SDT_B_MK1B902_2","PROTEASE RETROPEPSIN","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",5,"ASP B 241;ILE A 130;GLY A 128;PRO A  64;VAL A  65","None","0.97A","1sdtB-3it4B:undetectable","1sdtB-3it4B:19.80"],["1T3R_A_017A1200_1","PROTEASE RETROPEPSIN","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",5,"LEU A  66;GLY A  92;ASP A  98;ILE A 130;VAL A  65","None","0.86A","1t3rA-3it4A:undetectable","1t3rA-3it4A:16.33"],["1YMX_A_CFXA1001_2","BETA-LACTAMASE CTX-M-9","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",4,"CYH B 352;PRO B 359;THR B 374;SER B 343","None","1.10A","1ymxA-3it4B:undetectable","1ymxA-3it4B:21.85"],["2BXQ_A_IMNA2001_1","SERUM ALBUMIN","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",5,"ALA B 211;ALA A  51;LEU A  72;LEU A  77;LEU B 260","None;None;GOL A 500 (-4.9A);None;None","1.18A","2bxqA-3it4B:undetectable","2bxqA-3it4B:16.87"],["2HZQ_A_STRA300_1","APOLIPOPROTEIN D","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",4,"THR A  68;ALA A  87;ASN B 240;LEU A 134","None","1.07A","2hzqA-3it4A:undetectable","2hzqA-3it4A:21.76"],["2IEN_B_017B402_1","PROTEASE;PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",6,"LEU A  66;GLY A  92;ASP A  98;GLY A 131;ILE A 130;VAL A  65","None","1.47A","2ienA-3it4A:undetectable","2ienA-3it4A:16.26"],["2IEO_A_017A402_2","PROTEASE;PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",5,"LEU A  66;GLY A  92;ASP A  98;ILE A 130;VAL A  65","None","0.76A","2ieoB-3it4A:undetectable","2ieoB-3it4A:17.65"],["2NMZ_B_ROCB401_2","PROTEASE;PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",3,"ARG A 133;VAL A 124;THR A 102","None","0.83A","2nmzA-3it4A:undetectable","2nmzA-3it4A:17.16"],["2NNK_A_ROCA401_2","PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",3,"ARG A 133;VAL A 124;THR A 102","None","0.84A","2nnkA-3it4A:undetectable","2nnkA-3it4A:17.65"],["2NNK_A_ROCA401_3","PROTEASE;PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",5,"LEU A  66;GLY A  92;ASP A  98;ILE A 130;VAL A  65","None","0.73A","2nnkB-3it4A:undetectable","2nnkB-3it4A:17.65"],["2O4P_A_TPVA300_1","PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",5,"ASP B 241;ILE A 130;GLY A 128;PRO A  64;VAL A  65","None","1.00A","2o4pA-3it4B:undetectable","2o4pA-3it4B:19.21"],["2OPX_A_DXCA1003_0","ALDEHYDE DEHYDROGENASE A","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",4,"ILE B 335;LEU B 337;ASP B 376;ALA B 299","None","0.93A","2opxA-3it4B:undetectable","2opxA-3it4B:20.00"],["2VH3_B_DAHB2_1","RANASMURFIN","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",4,"ALA B 209;GLY A  46;SER B 251;ALA B 250","None","0.81A","2vh3B-3it4B:undetectable","2vh3B-3it4B:21.79"],["2X1L_A_ADNA601_1","METHIONYL-TRNA SYNTHETASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",5,"ALA A  87;ALA A  62;GLY A  92;GLY A 131;ILE A 130","None","1.08A","2x1lA-3it4A:undetectable","2x1lA-3it4A:19.19"],["2XAD_E_GCSE710_1","N-ACYL GLM PEUDO-TEICOPLANIN DEACETYLASE;TEICOPLANIN","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",4,"HIS A 178;ASP B 259;HIS A 179;ASP A 180","None","1.12A","2xadA-3it4A:undetectable","2xadA-3it4A:22.63"],["2XAD_F_GCSF710_1","N-ACYL GLM PEUDO-TEICOPLANIN DEACETYLASE;TEICOPLANIN","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",4,"HIS A 178;ASP B 259;HIS A 179;ASP A 180","None","1.10A","2xadB-3it4A:undetectable","2xadB-3it4A:22.63"],["2XAD_G_GCSG710_1","N-ACYL GLM PEUDO-TEICOPLANIN DEACETYLASE;TEICOPLANIN","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",4,"HIS A 178;ASP B 259;HIS A 179;ASP A 180","None","1.11A","2xadC-3it4A:undetectable","2xadC-3it4A:22.63"],["3BVB_B_017B401_2","PROTEASE (RETROPEPSIN)","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",6,"LEU A  66;GLY A  92;ASP A  98;GLY A 131;ILE A 130;VAL A  65","None","1.41A","3bvbB-3it4A:undetectable","3bvbB-3it4A:16.26"],["3D1X_A_ROCA201_2","HIV-1 PROTEASE;HIV-1 PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",5,"LEU A  66;GLY A  92;ASP A  98;ILE A 130;VAL A  65","None","0.83A","3d1xB-3it4A:undetectable","3d1xB-3it4A:17.50"],["3D1Z_B_017B201_1","HIV-1 PROTEASE;HIV-1 PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",5,"ASP B 241;ILE A 130;GLY A 128;PRO A  64;VAL A  65","None","1.00A","3d1zA-3it4B:undetectable","3d1zA-3it4B:18.91"],["3D20_A_017A201_2","HIV-1 PROTEASE;HIV-1 PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",5,"LEU A  66;GLY A  92;ASP A  98;ILE A 130;VAL A  65","None","0.78A","3d20B-3it4A:undetectable","3d20B-3it4A:18.00"],["3EKY_A_DR7A100_2","PROTEASE;PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",5,"ASP B 241;ILE A 130;GLY A 128;PRO A  64;VAL A  65","None","0.99A","3ekyB-3it4B:undetectable","3ekyB-3it4B:18.91"],["3EM3_B_478B200_2","PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",5,"ASP B 241;ILE A 130;GLY A 128;PRO A  64;VAL A  65","None","1.00A","3em3B-3it4B:undetectable","3em3B-3it4B:19.80"],["3IT4_C_BEZC503_0","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",4,"ARG A   9;GLN A  14;LEU A 154;HIS A 177","None","0.37A","3it4C-3it4A:38.0","3it4C-3it4A:100.00"],["3JW2_A_017A401_1","GAG-POL POLYPROTEIN","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",6,"LEU A  66;GLY A  92;ASP A  98;GLY A 131;ILE A 130;VAL A  65","None","1.46A","3jw2A-3it4A:undetectable","3jw2A-3it4A:16.26"],["3JW2_A_017A401_2","GAG-POL POLYPROTEIN;GAG-POL POLYPROTEIN","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",6,"LEU A  66;GLY A  92;ASP A  98;GLY A 131;ILE A 130;VAL A  65","None","1.48A","3jw2B-3it4A:undetectable","3jw2B-3it4A:16.26"],["3K4V_B_ROCB201_1","HIV-1 PROTEASE;HIV-1 PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",6,"LEU A  66;GLY A  92;ASP A  98;GLY A 131;ILE A 130;VAL A  65","None","1.50A","3k4vA-3it4A:undetectable","3k4vA-3it4A:16.26"],["3K4V_B_ROCB201_2","HIV-1 PROTEASE;HIV-1 PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",3,"ARG A 133;VAL A 124;THR A 102","None","0.83A","3k4vA-3it4A:undetectable","3k4vA-3it4A:16.26"],["3K4V_B_ROCB201_3","HIV-1 PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",6,"LEU A  66;GLY A  92;ASP A  98;GLY A 131;ILE A 130;VAL A  65","None","1.45A","3k4vB-3it4A:undetectable","3k4vB-3it4A:16.26"],["3KW4_A_TICA600_1","CYTOCHROME P450 2B4","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",5,"ILE B 306;ILE B 335;ALA B 329;ILE B 342;VAL B 375","None","0.97A","3kw4A-3it4B:undetectable","3kw4A-3it4B:18.83"],["3LZV_A_017A200_2","HIV-1 PROTEASE;HIV-1 PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",5,"ASP B 241;ILE A 130;GLY A 128;PRO A  64;VAL A  65","None","0.92A","3lzvB-3it4B:undetectable","3lzvB-3it4B:19.40"],["3NDT_A_ROCA101_2","PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",3,"ARG A 133;VAL A 124;THR A 102","None","0.64A","3ndtA-3it4A:undetectable","3ndtA-3it4A:16.26"],["3NDT_A_ROCA101_3","PROTEASE;PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",6,"LEU A  66;GLY A  92;ASP A  98;GLY A 131;ILE A 130;VAL A  65","None","1.38A","3ndtB-3it4A:undetectable","3ndtB-3it4A:16.26"],["3NDT_D_ROCD100_1","PROTEASE;PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",5,"LEU A  66;GLY A  92;ASP A  98;ILE A 130;VAL A  65","None","0.85A","3ndtC-3it4A:undetectable","3ndtC-3it4A:16.26"],["3NDU_D_ROCD100_1","PROTEASE;PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",5,"LEU A  66;GLY A  92;ASP A  98;ILE A 130;VAL A  65","None","0.79A","3nduC-3it4A:undetectable","3nduC-3it4A:16.26"],["3NUJ_B_478B401_1","PROTEASE;PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",5,"ASP B 241;ILE A 130;GLY A 128;PRO A  64;VAL A  65","None","0.93A","3nujA-3it4B:undetectable","3nujA-3it4B:17.79"],["3NUO_B_478B478_1","PROTEASE;PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",5,"ASP B 241;ILE A 130;GLY A 128;PRO A  64;VAL A  65","None","0.96A","3nuoA-3it4B:undetectable","3nuoA-3it4B:19.80"],["3O14_A_NIOA300_1","ANTI-ECFSIGMA FACTOR, CHRR","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",4,"ALA A  40;VAL A  16;VAL A  42;LEU A  82","None","0.80A","3o14A-3it4A:undetectable","3o14A-3it4A:27.08"],["3OXX_A_DR7A100_2","HIV-1 PROTEASE;HIV-1 PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",5,"ASP B 241;ILE A 130;GLY A 128;PRO A  64;VAL A  65","None","0.97A","3oxxB-3it4B:undetectable","3oxxB-3it4B:19.90"],["3OXX_C_DR7C100_1","HIV-1 PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",5,"ASP B 241;ILE A 130;GLY A 128;PRO A  64;VAL A  65","None","0.94A","3oxxC-3it4B:undetectable","3oxxC-3it4B:19.90"],["3PWM_B_017B402_1","PROTEASE;PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",5,"LEU A  66;GLY A  92;ASP A  98;ILE A 130;VAL A  65","None","0.85A","3pwmA-3it4A:undetectable","3pwmA-3it4A:16.75"],["3PWR_A_ROCA401_2","PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",3,"ARG A 133;VAL A 124;THR A 102","None","0.79A","3pwrA-3it4A:undetectable","3pwrA-3it4A:16.75"],["3R75_A_BEZA701_0","ANTHRANILATE\/PARA-AMINOBENZOATE SYNTHASES COMPONENT I","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis;Mycobacterium tuberculosis",5,"GLU B 280;GLY A 128;THR A 127;SER B 238;LYS B 200","None","1.27A","3r75A-3it4B:undetectable","3r75A-3it4B:16.56"],["3R75_B_BEZB701_0","ANTHRANILATE\/PARA-AMINOBENZOATE SYNTHASES COMPONENT I","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis;Mycobacterium tuberculosis",5,"GLU B 280;GLY A 128;THR A 127;SER B 238;LYS B 200","None","1.24A","3r75B-3it4B:undetectable","3r75B-3it4B:16.56"],["3TKG_B_ROCB801_2","PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",5,"LEU A  66;GLY A  92;ASP A  98;ILE A 130;VAL A  65","None","0.81A","3tkgB-3it4A:undetectable","3tkgB-3it4A:16.26"],["3TKW_B_017B401_2","PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",6,"LEU A  66;GLY A  92;ASP A  98;GLY A 131;ILE A 130;VAL A  65","None","1.38A","3tkwB-3it4A:undetectable","3tkwB-3it4A:16.26"],["3TL9_A_ROCA401_1","PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",6,"LEU A  66;GLY A  92;ASP A  98;GLY A 131;ILE A 130;VAL A  65","None","1.45A","3tl9A-3it4A:undetectable","3tl9A-3it4A:16.26"],["3TL9_A_ROCA401_2","PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",3,"ARG A 133;VAL A 124;THR A 102","None","0.87A","3tl9A-3it4A:undetectable","3tl9A-3it4A:16.26"],["4DQB_B_017B101_2","ASPARTYL PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",5,"LEU A  66;GLY A  92;ASP A  98;ILE A 130;VAL A  65","None","0.85A","4dqbB-3it4A:undetectable","4dqbB-3it4A:16.42"],["4DQE_B_017B101_2","ASPARTYL PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",5,"LEU A  66;GLY A  92;ASP A  98;ILE A 130;VAL A  65","None","0.82A","4dqeB-3it4A:undetectable","4dqeB-3it4A:16.58"],["4DQH_B_017B101_2","WILD-TYPE HIV-1 PROTEASE DIMER","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",5,"LEU A  66;GLY A  92;ASP A  98;ILE A 130;VAL A  65","None","0.85A","4dqhB-3it4A:undetectable","4dqhB-3it4A:16.42"],["4H1N_A_CGEA505_1","CYTOCHROME P450 2B4","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",5,"ILE B 306;ILE B 335;ALA B 329;ILE B 342;VAL B 375","None","0.92A","4h1nA-3it4B:undetectable","4h1nA-3it4B:19.54"],["4J7X_F_SASF805_1","SEPIAPTERIN REDUCTASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",5,"CYH B 268;PHE B 228;ASP B 241;MET B 201;GLY A 190","None","1.36A","4j7xF-3it4B:undetectable","4j7xF-3it4B:26.40"],["4JEC_B_478B401_1","HIV-1 PROTEASE;HIV-1 PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",6,"LEU A  66;GLY A  92;ASP A  98;GLY A 131;ILE A 130;VAL A  65","None","1.43A","4jecA-3it4A:undetectable","4jecA-3it4A:16.26"],["4KOE_H_TR6H101_1","DNA TOPOISOMERASE 4 SUBUNIT A;DNA TOPOISOMERASE 4 SUBUNIT A;DNA TOPOISOMERASE 4 SUBUNIT B;E-SITE DNA4","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",4,"ARG B 285;ASP B 278;GLY B 281;GLU B 398","None","0.83A","4koeA-3it4B:undetectable;4koeB-3it4B:undetectable;4koeD-3it4B:undetectable","4koeA-3it4B:19.26;4koeB-3it4B:19.26;4koeD-3it4B:20.51"],["4PD9_A_ADNA501_1","NUPC FAMILY PROTEIN","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",5,"GLY B 348;ALA B 349;VAL B 364;LEU B 366;ILE B 373","None","1.15A","4pd9A-3it4B:undetectable","4pd9A-3it4B:19.11"],["4Q1W_A_017A104_1","ASPARTYL PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",5,"LEU A  66;GLY A  92;ASP A  98;ILE A 130;VAL A  65","None","1.02A","4q1wA-3it4A:undetectable","4q1wA-3it4A:15.82"],["4TWD_A_377A402_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",5,"ALA B 215;ALA B 211;ALA B 209;SER B 247;ALA B 219","None","1.34A","4twdA-3it4B:undetectable;4twdB-3it4B:undetectable;4twdC-3it4B:undetectable;4twdD-3it4B:undetectable;4twdE-3it4B:undetectable","4twdA-3it4B:17.83;4twdB-3it4B:17.83;4twdC-3it4B:17.83;4twdD-3it4B:17.83;4twdE-3it4B:17.83"],["4YVG_A_SAMA301_0","TRNA (GUANINE-N(1)-)-METHYLTRANSFERASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis;Mycobacterium tuberculosis",5,"GLY A  15;GLY A 157;LEU B 205;GLY A 186;GLY A 185","None","1.11A","4yvgA-3it4A:undetectable","4yvgA-3it4A:23.95"],["4Z53_H_TR6H101_1","DNA TOPOISOMERASE 4 SUBUNIT B,DNA TOPOISOMERASE 4 SUBUNIT A;DNA TOPOISOMERASE 4 SUBUNIT B,DNA TOPOISOMERASE 4 SUBUNIT A;E-SITE DNA","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",4,"ARG B 285;ASP B 278;GLY B 281;GLU B 398","None","0.81A","4z53A-3it4B:undetectable;4z53B-3it4B:undetectable","4z53A-3it4B:15.66;4z53B-3it4B:15.66"],["5BTG_F_LFXF101_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCATGACC","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",5,"ARG B 285;ALA B 369;ASP B 278;GLY B 281;GLU B 398","None","1.43A","5btgA-3it4B:undetectable;5btgC-3it4B:undetectable;5btgD-3it4B:undetectable","5btgA-3it4B:20.20;5btgC-3it4B:20.20;5btgD-3it4B:22.01"],["5C0O_G_SAMG301_0","TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE TRMI","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis;Mycobacterium tuberculosis",5,"ALA A  18;GLY A 186;GLY A  15;GLY A 157;LEU B 205","None","0.97A","5c0oG-3it4A:undetectable","5c0oG-3it4A:22.56"],["5KR0_A_478A101_2","PROTEASE E35D-APV;PROTEASE E35D-APV","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN","Mycobacterium tuberculosis",6,"LEU A  66;GLY A  92;ASP A  98;GLY A 131;ILE A 130;VAL A  65","None","1.50A","5kr0B-3it4A:undetectable","5kr0B-3it4A:16.26"],["5ND2_B_TA1B601_1","TUBULIN BETA-2B CHAIN","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",5,"VAL B 364;GLU B 363;LEU B 327;ALA B 361;ARG B 325","None;None;None;None;ACT B 601 (-4.0A)","1.29A","5nd2B-3it4B:undetectable","5nd2B-3it4B:18.43"],["5SYF_B_TA1B502_1","TUBULIN BETA CHAIN","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis",5,"VAL B 243;LEU A  10;ASP B 269;ARG A  12;GLN A  14","None","1.32A","5syfB-3it4B:undetectable","5syfB-3it4B:20.48"],["5WYQ_A_SAMA401_0","TRNA (GUANINE-N(1)-)-METHYLTRANSFERASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis;Mycobacterium tuberculosis",5,"GLY A  15;GLY A 157;LEU B 205;GLY A 186;GLY A 185","None","1.12A","5wyqA-3it4A:undetectable","5wyqA-3it4A:23.20"],["6DIL_B_TPVB201_0","HIV-1 PROTEASE","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis;Mycobacterium tuberculosis",5,"ASP B 241;ILE A 130;GLY A 128;PRO A  64;VAL A  65","None","0.98A","6dilA-3it4B:undetectable","6dilA-3it4B:19.00"],["6I5Z_D_SAMD401_0","O-METHYLTRANSFERASE 1","3it4","ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ ALPHA CHAIN;ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ BETA CHAIN","Mycobacterium tuberculosis;Mycobacterium tuberculosis",5,"SER B 248;GLY A  15;GLY A 185;LEU B 271;VAL B 267","None","1.21A","6i5zD-3it4B:undetectable","6i5zD-3it4B:18.86"]]