SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3it8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3it8 2L PROTEIN
(Tanapox
virus) 		5 / 9 GLY D 108
GLY D 105
GLU D 159
ARG D 119
GLY D 246
 None
 1.07A 1jhoA-3it8D:
undetectable		 1jhoA-3it8D:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3it8 2L PROTEIN
(Tanapox
virus) 		5 / 9 GLY D 108
GLY D 105
GLU D 159
ARG D 119
GLY D 246
 None
 1.04A 1jhrA-3it8D:
undetectable		 1jhrA-3it8D:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3it8 2L PROTEIN
(Tanapox
virus) 		5 / 9 GLY D 108
GLY D 105
GLU D 159
ARG D 119
GLY D 246
 None
 1.04A 1jhyA-3it8D:
undetectable		 1jhyA-3it8D:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3it8 2L PROTEIN
(Tanapox
virus) 		5 / 9 GLY D 108
GLY D 105
GLU D 159
ARG D 119
GLY D 246
 None
 1.08A 1l4nA-3it8D:
undetectable		 1l4nA-3it8D:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3it8 2L PROTEIN
(Tanapox
virus) 		5 / 9 GLY D 108
GLY D 105
GLU D 159
ARG D 119
GLY D 246
 None
 1.06A 1l5kA-3it8D:
undetectable		 1l5kA-3it8D:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3it8 2L PROTEIN
(Tanapox
virus) 		5 / 9 GLY D 108
GLY D 105
GLU D 159
ARG D 119
GLY D 246
 None
 1.06A 1l5lA-3it8D:
undetectable		 1l5lA-3it8D:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3it8 2L PROTEIN
(Tanapox
virus) 		5 / 9 GLY D 108
GLY D 105
GLU D 159
ARG D 119
GLY D 246
 None
 1.07A 1l5mA-3it8D:
undetectable		 1l5mA-3it8D:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWE_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3it8 2L PROTEIN
(Tanapox
virus) 		4 / 7 LEU D  93
TYR D 120
GLY D  96
TYR D   7
 None
 1.01A 1lweA-3it8D:
undetectable		 1lweA-3it8D:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M9J_B_CLWB907_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)		 3it8 2L PROTEIN
(Tanapox
virus) 		4 / 5 PRO D 116
VAL D 110
TYR D 243
GLU D 247
 None
 1.49A 1m9jB-3it8D:
undetectable		 1m9jB-3it8D:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_B_ADNB1502_1
(CLASS B ACID
PHOSPHATASE)		 3it8 2L PROTEIN
(Tanapox
virus) 		4 / 7 PHE D 207
THR D 182
TYR D 208
LYS D 180
 None
 1.17A 1rmtB-3it8D:
undetectable		 1rmtB-3it8D:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 3it8 2L PROTEIN
(Tanapox
virus) 		5 / 12 ILE D  33
ALA D  48
ASP D  23
PHE D  66
PRO D  60
 None
 1.10A 3jb1A-3it8D:
undetectable		 3jb1A-3it8D:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 3it8 2L PROTEIN
(Tanapox
virus) 		4 / 6 ILE D  53
TYR D   5
TYR D 170
PHE D  51
 None
 1.16A 4g10A-3it8D:
undetectable		 4g10A-3it8D:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3it8 2L PROTEIN
(Tanapox
virus) 		5 / 9 GLY D 108
GLY D 105
GLU D 159
ARG D 119
GLY D 246
 None
 1.03A 4kqiA-3it8D:
undetectable		 4kqiA-3it8D:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_ACTA608_0
(SERUM ALBUMIN)		 3it8 2L PROTEIN
(Tanapox
virus) 		3 / 3 LYS D 129
ARG D 119
HIS D 121
 None
 1.24A 4zbrA-3it8D:
undetectable		 4zbrA-3it8D:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3it8 2L PROTEIN
(Tanapox
virus) 		3 / 3 TYR D  98
THR D   2
THR D 100
 None
 0.73A 5aoxB-3it8D:
undetectable		 5aoxB-3it8D:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3it8 2L PROTEIN
(Tanapox
virus) 		3 / 3 TYR D  98
THR D   2
THR D 100
 None
 0.72A 5aoxE-3it8D:
undetectable		 5aoxE-3it8D:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)		 3it8 2L PROTEIN
(Tanapox
virus) 		3 / 3 ILE D 213
THR D 214
PRO D 245
 None
 0.57A 6ncsA-3it8D:
undetectable		 6ncsA-3it8D:
22.52