SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3itd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 3itd 17BETA-HYDROXYSTEROI
D DEHYDROGENASE
(Curvularia
lunata) 		4 / 8 PHE A 132
LEU A 150
ALA A 194
VAL A 262
 None
 0.58A 1epbB-3itdA:
undetectable		 1epbB-3itdA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)		 3itd 17BETA-HYDROXYSTEROI
D DEHYDROGENASE
(Curvularia
lunata) 		4 / 7 PHE A  87
THR A  24
VAL A  23
ALA A  90
 None
 1.09A 1fo4B-3itdA:
undetectable		 1fo4B-3itdA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3itd 17BETA-HYDROXYSTEROI
D DEHYDROGENASE
(Curvularia
lunata) 		4 / 5 ASP A 175
VAL A 174
SER A 170
ASP A 158
 None
 1.10A 1n2xB-3itdA:
9.0		 1n2xB-3itdA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3itd 17BETA-HYDROXYSTEROI
D DEHYDROGENASE
(Curvularia
lunata) 		3 / 3 SER A  68
GLY A  67
ARG A  15
 None
 0.52A 1t9wA-3itdA:
undetectable		 1t9wA-3itdA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3itd 17BETA-HYDROXYSTEROI
D DEHYDROGENASE
(Curvularia
lunata) 		4 / 7 ARG A  28
ALA A  32
PRO A 240
ALA A  33
 None
 1.08A 2ejfA-3itdA:
undetectable		 2ejfA-3itdA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_A_SC2A1290_1
(FICOLIN-2)		 3itd 17BETA-HYDROXYSTEROI
D DEHYDROGENASE
(Curvularia
lunata) 		4 / 5 SER A  68
LEU A  41
GLY A  39
ARG A  15
 None
 0.93A 2j2pA-3itdA:
undetectable
2j2pB-3itdA:
undetectable		 2j2pA-3itdA:
22.30
2j2pB-3itdA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_0
(UNCHARACTERIZED
PROTEIN PH0793)		 3itd 17BETA-HYDROXYSTEROI
D DEHYDROGENASE
(Curvularia
lunata) 		5 / 12 SER A 170
ASN A 127
ASP A 266
THR A 264
PHE A 205
 None
 1.32A 3a25A-3itdA:
6.9		 3a25A-3itdA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 3itd 17BETA-HYDROXYSTEROI
D DEHYDROGENASE
(Curvularia
lunata) 		4 / 7 GLY A  31
ALA A  32
ALA A  56
ASP A  55
 None
 0.89A 3ur0B-3itdA:
undetectable		 3ur0B-3itdA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3itd 17BETA-HYDROXYSTEROI
D DEHYDROGENASE
(Curvularia
lunata) 		4 / 8 SER A 156
GLN A 131
ILE A  30
VAL A  34
 None
 0.99A 4dx7B-3itdA:
undetectable		 4dx7B-3itdA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 3itd 17BETA-HYDROXYSTEROI
D DEHYDROGENASE
(Curvularia
lunata) 		5 / 12 GLY A 238
VAL A 246
LEU A 265
PRO A 197
VAL A 195
 None
 0.99A 4gc9A-3itdA:
5.3		 4gc9A-3itdA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3itd 17BETA-HYDROXYSTEROI
D DEHYDROGENASE
(Curvularia
lunata) 		5 / 11 VAL A  34
ALA A  32
SER A 102
THR A 200
VAL A 243
 None
 1.07A 4kyaA-3itdA:
2.1		 4kyaA-3itdA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_E_FOLE703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3itd 17BETA-HYDROXYSTEROI
D DEHYDROGENASE
(Curvularia
lunata) 		5 / 11 VAL A  34
ALA A  32
SER A 102
THR A 200
VAL A 243
 None
 1.08A 4kyaE-3itdA:
undetectable		 4kyaE-3itdA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_G_FOLG703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3itd 17BETA-HYDROXYSTEROI
D DEHYDROGENASE
(Curvularia
lunata) 		5 / 11 VAL A  34
ALA A  32
SER A 102
THR A 200
VAL A 243
 None
 1.07A 4kyaG-3itdA:
2.2		 4kyaG-3itdA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3itd 17BETA-HYDROXYSTEROI
D DEHYDROGENASE
(Curvularia
lunata) 		5 / 12 ILE A  63
GLY A  39
HIS A  37
ALA A  35
VAL A  46
 None
 1.14A 5n0oB-3itdA:
undetectable		 5n0oB-3itdA:
21.14