SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ite'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3ite SIDN SIDEROPHORE
SYNTHETASE
(Epichloe
festucae) 		5 / 10 SER A 199
SER A  18
LEU A  56
VAL A  34
VAL A  92
 None
CL  A 559 (-3.0A)
None
None
None
 1.43A 1q23E-3iteA:
undetectable		 1q23E-3iteA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		 3ite SIDN SIDEROPHORE
SYNTHETASE
(Epichloe
festucae) 		5 / 12 LEU A 144
LEU A  66
ALA A  89
ILE A  90
ILE A  86
 None
 1.07A 2bxcA-3iteA:
undetectable		 2bxcA-3iteA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))		 3ite SIDN SIDEROPHORE
SYNTHETASE
(Epichloe
festucae) 		5 / 12 LEU A 225
VAL A 268
GLY A 250
LEU A  56
TYR A  53
 None
 1.13A 2cbrA-3iteA:
undetectable		 2cbrA-3iteA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 3ite SIDN SIDEROPHORE
SYNTHETASE
(Epichloe
festucae) 		5 / 12 LEU A  66
ALA A  89
TRP A  51
LEU A  81
ARG A 228
 None
None
None
None
SO4  A 558 (-4.7A)
 1.02A 2oaxC-3iteA:
undetectable		 2oaxC-3iteA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 3ite SIDN SIDEROPHORE
SYNTHETASE
(Epichloe
festucae) 		5 / 12 LEU A  66
ALA A  89
TRP A  51
LEU A  81
ARG A 228
 None
None
None
None
SO4  A 558 (-4.7A)
 1.03A 2oaxD-3iteA:
undetectable		 2oaxD-3iteA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3ite SIDN SIDEROPHORE
SYNTHETASE
(Epichloe
festucae) 		4 / 8 SER A 360
MET A 400
VAL A 373
ASN A 396
 None
 1.21A 2wekA-3iteA:
3.1		 2wekA-3iteA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3ite SIDN SIDEROPHORE
SYNTHETASE
(Epichloe
festucae) 		4 / 8 SER A 360
MET A 400
VAL A 373
ASN A 396
 None
 1.26A 2wekB-3iteA:
3.2		 2wekB-3iteA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_B_ACTB701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 3ite SIDN SIDEROPHORE
SYNTHETASE
(Epichloe
festucae) 		3 / 3 HIS A 270
GLY A 207
ILE A 206
 None
 0.61A 4k50A-3iteA:
undetectable		 4k50A-3iteA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_J_ACTJ701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 3ite SIDN SIDEROPHORE
SYNTHETASE
(Epichloe
festucae) 		3 / 3 HIS A 270
GLY A 207
ILE A 206
 None
 0.62A 4k50I-3iteA:
undetectable		 4k50I-3iteA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 3ite SIDN SIDEROPHORE
SYNTHETASE
(Epichloe
festucae) 		5 / 12 PHE A 263
ALA A 288
THR A 281
LEU A 256
LEU A 225
 None
 1.03A 4qzuC-3iteA:
undetectable		 4qzuC-3iteA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3ite SIDN SIDEROPHORE
SYNTHETASE
(Epichloe
festucae) 		4 / 5 ILE A 415
SER A 413
HIS A 346
ASP A 340
 None
 1.39A 4rzvB-3iteA:
1.4		 4rzvB-3iteA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XPB_A_COCA702_1
(TRANSPORTER)		 3ite SIDN SIDEROPHORE
SYNTHETASE
(Epichloe
festucae) 		5 / 10 PHE A 198
TYR A 174
GLY A 329
GLY A 235
MET A 237
 None
 1.19A 4xpbA-3iteA:
undetectable		 4xpbA-3iteA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3ite SIDN SIDEROPHORE
SYNTHETASE
(Epichloe
festucae) 		4 / 5 ALA A  25
TYR A  53
GLY A 349
LEU A 239
 None
 0.74A 5eslA-3iteA:
undetectable		 5eslA-3iteA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3ite SIDN SIDEROPHORE
SYNTHETASE
(Epichloe
festucae) 		5 / 12 GLY A  93
LEU A  81
ILE A  77
MET A 124
LEU A  56
 None
 0.97A 5ycnA-3iteA:
undetectable		 5ycnA-3iteA:
20.21