SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3itf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3itf PERIPLASMIC ADAPTOR
PROTEIN CPXP
(Escherichia
coli) 		3 / 3 ALA A 108
ARG A 109
LYS A  40
 None
 1.00A 3kp3B-3itfA:
2.5		 3kp3B-3itfA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_B_KANB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3itf PERIPLASMIC ADAPTOR
PROTEIN CPXP
(Escherichia
coli) 		3 / 3 ALA A 108
ARG A 109
LYS A  40
 None
 0.95A 3kp5B-3itfA:
undetectable		 3kp5B-3itfA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3itf PERIPLASMIC ADAPTOR
PROTEIN CPXP
(Escherichia
coli) 		3 / 3 MET A 120
GLN A 119
ARG A 122
 None
 1.04A 5m35B-3itfA:
2.5		 5m35B-3itfA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3itf PERIPLASMIC ADAPTOR
PROTEIN CPXP
(Escherichia
coli) 		3 / 3 MET A 120
GLN A 119
ARG A 122
 None
 1.01A 5m36A-3itfA:
2.0		 5m36A-3itfA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3itf PERIPLASMIC ADAPTOR
PROTEIN CPXP
(Escherichia
coli) 		3 / 3 MET A 120
GLN A 119
ARG A 122
 None
 1.03A 6fn9A-3itfA:
2.6		 6fn9A-3itfA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3itf PERIPLASMIC ADAPTOR
PROTEIN CPXP
(Escherichia
coli) 		3 / 3 MET A 120
GLN A 119
ARG A 122
 None
 1.03A 6fnaB-3itfA:
2.8		 6fnaB-3itfA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3itf PERIPLASMIC ADAPTOR
PROTEIN CPXP
(Escherichia
coli) 		3 / 3 MET A 120
GLN A 119
ARG A 122
 None
 1.03A 6fnbA-3itfA:
2.8		 6fnbA-3itfA:
19.66