SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3iu1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		4 / 7 LEU A 403
TYR A 401
ASN A 246
TYR A 180
 None
None
None
MYA  A1001 (-4.3A)
 1.34A 1afsA-3iu1A:
undetectable		 1afsA-3iu1A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		4 / 7 LEU A 403
TYR A 401
ASN A 246
TYR A 180
 None
None
None
MYA  A1001 (-4.3A)
 1.34A 1afsB-3iu1A:
undetectable		 1afsB-3iu1A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		4 / 7 LEU A 353
GLU A 370
LEU A 493
GLY A 492
 None
 0.79A 1n13D-3iu1A:
undetectable
1n13E-3iu1A:
undetectable		 1n13D-3iu1A:
12.69
1n13E-3iu1A:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		4 / 5 SER A 421
SER A 399
PHE A 461
VAL A 494
 None
 1.41A 1oipA-3iu1A:
undetectable		 1oipA-3iu1A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_0
(ESTROGEN RECEPTOR)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		5 / 12 LEU A 176
LEU A 161
LEU A 201
GLY A 213
LEU A 222
 None
 1.06A 2ouzA-3iu1A:
undetectable		 2ouzA-3iu1A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		5 / 9 TYR A 401
LEU A 176
LEU A 197
ALA A 200
PHE A 247
 None
 1.20A 2vcvD-3iu1A:
undetectable		 2vcvD-3iu1A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		5 / 9 TYR A 401
LEU A 176
LEU A 197
ALA A 200
PHE A 247
 None
 1.20A 2vcvH-3iu1A:
undetectable		 2vcvH-3iu1A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_I_ASDI1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		5 / 9 TYR A 401
LEU A 176
LEU A 197
ALA A 200
PHE A 247
 None
 1.15A 2vcvI-3iu1A:
undetectable		 2vcvI-3iu1A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		4 / 6 LEU A 493
SER A 227
PHE A 247
GLU A 244
 None
 1.13A 2vn1B-3iu1A:
undetectable		 2vn1B-3iu1A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		3 / 3 ASN A 409
HIS A 410
VAL A 309
 None
 0.80A 3elzB-3iu1A:
undetectable		 3elzB-3iu1A:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_B_ACTB901_0
(PYRANOSE 2-OXIDASE)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		4 / 6 SER A 421
PHE A 450
PHE A 461
ASN A 458
 None
 1.31A 3lskB-3iu1A:
undetectable		 3lskB-3iu1A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		5 / 12 GLY A 224
GLY A 213
LEU A 248
THR A 174
LEU A 175
 None
None
MYA  A1001 (-4.1A)
None
None
 1.04A 3mteB-3iu1A:
undetectable		 3mteB-3iu1A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_B_SAMB6735_0
(16S RRNA METHYLASE)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		5 / 12 GLY A 224
GLY A 213
LEU A 248
THR A 174
LEU A 175
 None
None
MYA  A1001 (-4.1A)
None
None
 1.03A 3p2kB-3iu1A:
undetectable		 3p2kB-3iu1A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		4 / 5 PHE A 225
TYR A 192
LEU A 254
ARG A 189
 None
 1.27A 3sudD-3iu1A:
undetectable		 3sudD-3iu1A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_2
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		3 / 3 LEU A 441
MET A 435
ASP A 396
 None
 0.89A 3v5wA-3iu1A:
undetectable		 3v5wA-3iu1A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_A_P1BA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		5 / 12 PRO A 203
TRP A 199
LEU A 495
ILE A 229
TYR A 476
 None
 1.29A 4a79A-3iu1A:
undetectable		 4a79A-3iu1A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		5 / 12 PRO A 203
TRP A 199
LEU A 495
ILE A 229
TYR A 476
 None
 1.28A 4a79B-3iu1A:
undetectable		 4a79B-3iu1A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		3 / 3 ASP A 141
LYS A 142
ASP A 143
 None
 0.83A 4a7tA-3iu1A:
undetectable		 4a7tA-3iu1A:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		4 / 8 PHE A 375
PHE A 397
PHE A 422
LEU A 357
 None
 0.86A 4ejgB-3iu1A:
undetectable		 4ejgB-3iu1A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		3 / 3 GLU A 370
THR A 354
HIS A 350
 None
 0.81A 4q15A-3iu1A:
undetectable		 4q15A-3iu1A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		3 / 3 GLU A 370
THR A 354
HIS A 350
 None
 0.79A 4q15B-3iu1A:
undetectable		 4q15B-3iu1A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		4 / 8 PHE A 422
TRP A 199
ASN A 246
ILE A 233
 None
 0.82A 4qoiA-3iu1A:
undetectable
4qoiB-3iu1A:
undetectable		 4qoiA-3iu1A:
19.01
4qoiB-3iu1A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		3 / 3 GLU A 370
THR A 354
HIS A 350
 None
 0.81A 4ydqB-3iu1A:
undetectable		 4ydqB-3iu1A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		3 / 3 SER A 421
SER A 399
PHE A 461
 None
 0.87A 5mugA-3iu1A:
undetectable		 5mugA-3iu1A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_E_SAME501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		5 / 9 LEU A 301
PRO A 303
GLY A 446
SER A 300
LEU A 329
 None
 1.35A 5o96E-3iu1A:
undetectable
5o96F-3iu1A:
undetectable		 5o96E-3iu1A:
21.55
5o96F-3iu1A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		4 / 5 ARG A 322
MET A 320
THR A 319
LEU A 314
 None
 1.42A 5x19J-3iu1A:
undetectable		 5x19J-3iu1A:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		4 / 5 ARG A 322
MET A 320
THR A 319
LEU A 314
 None
 1.37A 5x1bJ-3iu1A:
undetectable		 5x1bJ-3iu1A:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		4 / 6 PHE A 277
ILE A 145
ASN A 144
ASP A 143
 None
 1.50A 6dhbA-3iu1A:
undetectable		 6dhbA-3iu1A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_ACTA405_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		4 / 6 THR A 238
PRO A 137
GLN A 278
ILE A 235
 None
 1.21A 6ef6A-3iu1A:
undetectable		 6ef6A-3iu1A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_1
(TUBULIN BETA CHAIN)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		5 / 12 LEU A 329
ALA A 419
PHE A 450
LEU A 439
LEU A 398
 None
 1.11A 6ew0G-3iu1A:
undetectable		 6ew0G-3iu1A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		4 / 7 ILE A 381
GLN A 378
GLU A 372
HIS A 373
 None
 0.96A 6j20A-3iu1A:
undetectable		 6j20A-3iu1A:
21.43