SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3iu3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UIL_H_QI9H1223_0
(FAB 314.1)		 3iu3 HEAVY CHAIN OF FAB
FRAGMENT OF
BASILIXIMAB
(Homo
sapiens;
Mus
musculus) 		5 / 12 TRP A  31
HIS A  33
ALA A  48
SER A  57
PHE A 102
 None
 0.35A 4uilH-3iu3A:
25.4
4uilL-3iu3A:
12.5		 4uilH-3iu3A:
76.82
4uilL-3iu3A:
29.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UIN_H_QI9H1226_0
(FAB 314.3)		 3iu3 HEAVY CHAIN OF FAB
FRAGMENT OF
BASILIXIMAB
(Homo
sapiens;
Mus
musculus) 		5 / 12 TRP A  31
HIS A  33
TRP A  45
SER A  57
PHE A 102
 None
 0.40A 4uinH-3iu3A:
26.7
4uinL-3iu3A:
17.7		 4uinH-3iu3A:
74.09
4uinL-3iu3A:
29.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3iu3 HEAVY CHAIN OF FAB
FRAGMENT OF
BASILIXIMAB
(Homo
sapiens;
Mus
musculus) 		5 / 11 SER A 190
GLY A 136
THR A 137
ALA A 138
THR A 133
 None
 0.97A 5bxnH-3iu3A:
undetectable
5bxnI-3iu3A:
undetectable		 5bxnH-3iu3A:
20.90
5bxnI-3iu3A:
22.61