SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3iu5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZMB_A_PXBA692_1 (LACTOTRANSFERRIN)	3iu5	PROTEIN POLYBROMO-1 (Homo sapiens)	3 / 3	PRO A 91 GLU A 86 TYR A 84	None	0.73A	2zmbA-3iu5A: undetectable	2zmbA-3iu5A: 15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K8M_A_ACRA720_1 (ALPHA-AMYLASE, SUSG)	3iu5	PROTEIN POLYBROMO-1 (Homo sapiens)	4 / 7	TYR A 144 GLU A 52 LEU A 145 ASN A 149	None	1.18A	3k8mA-3iu5A: undetectable	3k8mA-3iu5A: 10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5C0O_G_SAMG301_1 (TRNA (ADENINE(58)-N(1))-M ETHYLTRANSFERASE TRMI)	3iu5	PROTEIN POLYBROMO-1 (Homo sapiens)	3 / 3	GLU A 52 HIS A 51 ASP A 59	None	0.84A	5c0oG-3iu5A: undetectable	5c0oG-3iu5A: 13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_G_SAMG301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	3iu5	PROTEIN POLYBROMO-1 (Homo sapiens)	5 / 12	ALA A 136 ASP A 93 GLN A 98 PHE A 72 GLU A 70	None	1.34A	5hfjG-3iu5A: undetectable	5hfjG-3iu5A: 17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WWS_B_SAMB501_0 (PUTATIVE METHYLTRANSFERASE NSUN6)	3iu5	PROTEIN POLYBROMO-1 (Homo sapiens)	5 / 12	ALA A 75 PRO A 76 ASP A 93 LYS A 96 ILE A 92	None	1.25A	5wwsB-3iu5A: undetectable	5wwsB-3iu5A: 14.47

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2ZMB_A_PXBA692_1","LACTOTRANSFERRIN","3iu5","PROTEIN POLYBROMO-1","Homo sapiens",3,"PRO A  91;GLU A  86;TYR A  84","None","0.73A","2zmbA-3iu5A:undetectable","2zmbA-3iu5A:15.36"],["3K8M_A_ACRA720_1","ALPHA-AMYLASE, SUSG","3iu5","PROTEIN POLYBROMO-1","Homo sapiens",4,"TYR A 144;GLU A  52;LEU A 145;ASN A 149","None","1.18A","3k8mA-3iu5A:undetectable","3k8mA-3iu5A:10.61"],["5C0O_G_SAMG301_1","TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE TRMI","3iu5","PROTEIN POLYBROMO-1","Homo sapiens",3,"GLU A  52;HIS A  51;ASP A  59","None","0.84A","5c0oG-3iu5A:undetectable","5c0oG-3iu5A:13.73"],["5HFJ_G_SAMG301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","3iu5","PROTEIN POLYBROMO-1","Homo sapiens",5,"ALA A 136;ASP A  93;GLN A  98;PHE A  72;GLU A  70","None","1.34A","5hfjG-3iu5A:undetectable","5hfjG-3iu5A:17.60"],["5WWS_B_SAMB501_0","PUTATIVE METHYLTRANSFERASE NSUN6","3iu5","PROTEIN POLYBROMO-1","Homo sapiens",5,"ALA A  75;PRO A  76;ASP A  93;LYS A  96;ILE A  92","None","1.25A","5wwsB-3iu5A:undetectable","5wwsB-3iu5A:14.47"]]