SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3iuk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		3 / 3 ALA A 454
VAL A 263
TRP A 472
 None
 0.91A 1bdwA-3iukA:
undetectable
1bdwB-3iukA:
undetectable		 1bdwA-3iukA:
2.52
1bdwB-3iukA:
2.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		4 / 7 LEU A  88
THR A  60
LEU A  62
LEU A  67
 None
 0.87A 1gtiB-3iukA:
undetectable		 1gtiB-3iukA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_A_LPRA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		6 / 12 THR A 382
HIS A 385
GLU A 386
HIS A 391
GLU A 420
TYR A 514
 None
MG  A 560 ( 4.9A)
MG  A 560 (-2.6A)
MG  A 560 (-3.5A)
MG  A 560 ( 3.9A)
None
 0.83A 1j36A-3iukA:
7.8		 1j36A-3iukA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_B_LPRB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		6 / 12 THR A 382
HIS A 385
GLU A 386
HIS A 391
GLU A 420
TYR A 514
 None
MG  A 560 ( 4.9A)
MG  A 560 (-2.6A)
MG  A 560 (-3.5A)
MG  A 560 ( 3.9A)
None
 0.84A 1j36B-3iukA:
7.8		 1j36B-3iukA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J37_A_X8ZA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		5 / 11 HIS A 385
GLU A 386
HIS A 391
GLU A 420
TYR A 514
 MG  A 560 ( 4.9A)
MG  A 560 (-2.6A)
MG  A 560 (-3.5A)
MG  A 560 ( 3.9A)
None
 0.85A 1j37A-3iukA:
5.5		 1j37A-3iukA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J37_B_X8ZB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		5 / 11 HIS A 385
GLU A 386
HIS A 391
GLU A 420
TYR A 514
 MG  A 560 ( 4.9A)
MG  A 560 (-2.6A)
MG  A 560 (-3.5A)
MG  A 560 ( 3.9A)
None
 0.86A 1j37B-3iukA:
8.6		 1j37B-3iukA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_0
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		5 / 12 GLY A 547
ASN A 545
GLY A 390
THR A 397
ALA A 396
 None
 0.98A 1jg4A-3iukA:
undetectable		 1jg4A-3iukA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		5 / 12 HIS A 385
GLU A 386
HIS A 391
GLU A 420
TYR A 514
 MG  A 560 ( 4.9A)
MG  A 560 (-2.6A)
MG  A 560 (-3.5A)
MG  A 560 ( 3.9A)
None
 0.92A 1o86A-3iukA:
6.4		 1o86A-3iukA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		3 / 3 GLU A 386
HIS A 385
HIS A 391
 MG  A 560 (-2.6A)
MG  A 560 ( 4.9A)
MG  A 560 (-3.5A)
 0.68A 1oe2A-3iukA:
undetectable		 1oe2A-3iukA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		5 / 6 GLY A 509
GLN A 510
TRP A 507
ALA A 244
SER A 247
 None
 1.49A 1p6kA-3iukA:
undetectable		 1p6kA-3iukA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		4 / 8 LEU A 544
TYR A 425
GLY A 419
LEU A 393
 None
 0.90A 1s1xA-3iukA:
undetectable		 1s1xA-3iukA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		3 / 3 PHE A 458
ARG A 471
ASN A 489
 None
 0.87A 1xzxX-3iukA:
undetectable		 1xzxX-3iukA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		4 / 5 GLY A 509
GLN A 510
TRP A 507
SER A 247
 None
 1.28A 1zzuA-3iukA:
undetectable		 1zzuA-3iukA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		4 / 6 GLU A 465
ASP A 234
PHE A 501
ARG A 163
 None
 1.40A 2a3bB-3iukA:
undetectable		 2a3bB-3iukA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		5 / 12 HIS A 385
GLU A 386
HIS A 391
GLU A 420
TYR A 514
 MG  A 560 ( 4.9A)
MG  A 560 (-2.6A)
MG  A 560 (-3.5A)
MG  A 560 ( 3.9A)
None
 0.89A 2c6nA-3iukA:
3.7		 2c6nA-3iukA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		5 / 12 HIS A 385
GLU A 386
HIS A 391
GLU A 420
TYR A 514
 MG  A 560 ( 4.9A)
MG  A 560 (-2.6A)
MG  A 560 (-3.5A)
MG  A 560 ( 3.9A)
None
 0.94A 2c6nB-3iukA:
6.6		 2c6nB-3iukA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		3 / 3 SER A 541
HIS A 392
ASP A 316
 None
 0.78A 2oxtA-3iukA:
undetectable		 2oxtA-3iukA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X8Z_A_X8ZA1615_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		5 / 11 HIS A 385
GLU A 386
HIS A 391
GLU A 420
TYR A 514
 MG  A 560 ( 4.9A)
MG  A 560 (-2.6A)
MG  A 560 (-3.5A)
MG  A 560 ( 3.9A)
None
 0.90A 2x8zA-3iukA:
7.6		 2x8zA-3iukA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		5 / 12 HIS A 385
GLU A 386
HIS A 391
GLU A 420
TYR A 514
 MG  A 560 ( 4.9A)
MG  A 560 (-2.6A)
MG  A 560 (-3.5A)
MG  A 560 ( 3.9A)
None
 0.92A 2x91A-3iukA:
7.9		 2x91A-3iukA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD6_0
(GRAMICIDIN A)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		4 / 5 TRP A 365
TRP A 364
ALA A 341
VAL A 367
 None
 1.34A 2xdcC-3iukA:
undetectable
2xdcD-3iukA:
undetectable		 2xdcC-3iukA:
2.52
2xdcD-3iukA:
2.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF6_0
(GRAMICIDIN A)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		4 / 5 TRP A 365
TRP A 364
ALA A 341
VAL A 367
 None
 1.34A 2xdcE-3iukA:
undetectable
2xdcF-3iukA:
undetectable		 2xdcE-3iukA:
2.52
2xdcF-3iukA:
2.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_D_TC9D1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		4 / 8 TYR A 146
ILE A 143
ASP A 113
SER A 109
 None
 1.11A 2xytE-3iukA:
undetectable		 2xytE-3iukA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_D_DVAD6_0
(VAL-GRAMICIDIN A)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		4 / 5 TRP A 365
TRP A 364
ALA A 341
VAL A 367
 None
 1.32A 2y5mC-3iukA:
undetectable
2y5mD-3iukA:
undetectable		 2y5mC-3iukA:
2.52
2y5mD-3iukA:
2.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF6_0
(VAL-GRAMICIDIN A)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		4 / 5 TRP A 365
TRP A 364
ALA A 341
VAL A 367
 None
 1.32A 2y5mE-3iukA:
undetectable
2y5mF-3iukA:
undetectable		 2y5mE-3iukA:
2.52
2y5mF-3iukA:
2.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD6_0
(VAL-GRAMICIDIN A)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		4 / 5 TRP A 365
TRP A 364
ALA A 341
VAL A 367
 None
 1.32A 2y6nC-3iukA:
undetectable
2y6nD-3iukA:
undetectable		 2y6nC-3iukA:
2.52
2y6nD-3iukA:
2.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF6_0
(VAL-GRAMICIDIN A)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		4 / 5 TRP A 365
TRP A 364
ALA A 341
VAL A 367
 None
 1.33A 2y6nE-3iukA:
undetectable
2y6nF-3iukA:
undetectable		 2y6nE-3iukA:
2.52
2y6nF-3iukA:
2.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		4 / 7 ASN A 138
ALA A 211
ALA A 210
ALA A 214
 None
 0.80A 3a2qA-3iukA:
undetectable		 3a2qA-3iukA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		5 / 12 LEU A 558
ALA A 557
VAL A 553
LEU A  88
LEU A  67
 None
 1.29A 3b0wB-3iukA:
undetectable		 3b0wB-3iukA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_A_GJZA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		4 / 6 LEU A 196
ILE A 132
ALA A 133
THR A 208
 None
 1.07A 3mdrA-3iukA:
undetectable		 3mdrA-3iukA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		4 / 6 ALA A 160
ILE A 165
LEU A 104
ALA A 153
 None
 0.86A 3r9sA-3iukA:
undetectable		 3r9sA-3iukA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		4 / 6 ALA A 160
ILE A 165
LEU A 104
ALA A 153
 None
 0.84A 3r9sC-3iukA:
undetectable		 3r9sC-3iukA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		5 / 12 ALA A 111
LEU A 104
ASN A 105
ILE A 169
ILE A 165
 None
 1.03A 3ut5B-3iukA:
undetectable		 3ut5B-3iukA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		3 / 3 ARG A 135
GLU A  42
THR A  34
 None
 0.94A 3v4tA-3iukA:
undetectable		 3v4tA-3iukA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C2P_A_X8ZA709_1
(ANGIOTENSIN-CONVERTI
NG ENZYME)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		5 / 11 HIS A 385
GLU A 386
HIS A 391
GLU A 420
TYR A 514
 MG  A 560 ( 4.9A)
MG  A 560 (-2.6A)
MG  A 560 (-3.5A)
MG  A 560 ( 3.9A)
None
 0.83A 4c2pA-3iukA:
9.9		 4c2pA-3iukA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		5 / 11 ILE A 114
ALA A 142
GLY A 141
GLU A 144
GLY A  52
 None
 1.14A 4e47A-3iukA:
undetectable		 4e47A-3iukA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_C_SAMC800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		5 / 11 ILE A 114
ALA A 142
GLY A 141
GLU A 144
GLY A  52
 None
 1.12A 4e47C-3iukA:
undetectable		 4e47C-3iukA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_C_SAMC401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		5 / 11 ILE A 114
ALA A 142
GLY A 141
GLU A 144
GLY A  52
 None
 1.14A 4jdsC-3iukA:
undetectable		 4jdsC-3iukA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		5 / 12 ILE A 114
ALA A 142
GLY A 141
GLU A 144
GLY A  52
 None
 1.15A 4jlgA-3iukA:
undetectable		 4jlgA-3iukA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM0_A_CP6A201_1
(DIHYDROFOLATE
REDUCTASE)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		5 / 10 ALA A 136
THR A  34
ILE A 117
TYR A  45
THR A 208
 None
 1.26A 4km0A-3iukA:
undetectable		 4km0A-3iukA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		5 / 11 LEU A 536
TYR A 425
ILE A 524
PHE A 534
LEU A 559
 None
 1.29A 4lhmA-3iukA:
undetectable		 4lhmA-3iukA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_B_AERB602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		5 / 9 ALA A 244
PHE A 248
ASN A 106
ILE A 107
GLY A 506
 None
 1.25A 4r20B-3iukA:
undetectable		 4r20B-3iukA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		5 / 11 ILE A 114
ALA A 142
GLY A 141
GLU A 144
GLY A  52
 None
 1.14A 5ayfA-3iukA:
undetectable		 5ayfA-3iukA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		4 / 5 LEU A 255
TYR A 259
LEU A 464
TYR A 241
 None
 1.38A 5ki6A-3iukA:
undetectable		 5ki6A-3iukA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		4 / 5 GLY A 509
GLN A 510
TRP A 507
SER A 247
 None
 1.33A 5vunA-3iukA:
undetectable		 5vunA-3iukA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_A_TRPA403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		4 / 8 ARG A 556
THR A  80
ILE A  14
PRO A  72
 None
 1.10A 6a4iA-3iukA:
undetectable		 6a4iA-3iukA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 3iuk UNCHARACTERIZED
PROTEIN
(Paenarthrobacter
aurescens) 		5 / 12 GLY A 390
PRO A 368
VAL A 395
GLU A 420
GLY A 419
 None
None
None
MG  A 560 ( 3.9A)
None
 1.28A 6gngA-3iukA:
undetectable		 6gngA-3iukA:
24.18