SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3iuv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XZX_X_T3X500_1 (THYROID HORMONE RECEPTOR BETA-1)	3iuv	UNCHARACTERIZED TETR FAMILY PROTEIN (Streptomyces coelicolor)	5 / 12	ILE A 13 ALA A 16 ARG A 19 LEU A 42 HIS A 31	None	1.21A	1xzxX-3iuvA: undetectable	1xzxX-3iuvA: 22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Y0X_X_T44X500_1 (THYROID HORMONE RECEPTOR BETA-1)	3iuv	UNCHARACTERIZED TETR FAMILY PROTEIN (Streptomyces coelicolor)	5 / 12	ILE A 13 ALA A 16 ARG A 19 LEU A 42 HIS A 31	None	1.24A	1y0xX-3iuvA: undetectable	1y0xX-3iuvA: 22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H77_A_T3A1_1 (THRA PROTEIN)	3iuv	UNCHARACTERIZED TETR FAMILY PROTEIN (Streptomyces coelicolor)	5 / 12	ILE A 13 ALA A 16 ARG A 19 LEU A 42 HIS A 31	None	1.13A	2h77A-3iuvA: undetectable	2h77A-3iuvA: 24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWW_A_SFXA801_1 (TRANSPORTER)	3iuv	UNCHARACTERIZED TETR FAMILY PROTEIN (Streptomyces coelicolor)	5 / 12	LEU A 92 GLY A 93 LEU A 96 ILE A 153 ASP A 165	None	1.11A	3gwwA-3iuvA: undetectable	3gwwA-3iuvA: 15.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HTH_B_PRLB201_0 (EBRA REPRESSOR)	3iuv	UNCHARACTERIZED TETR FAMILY PROTEIN (Streptomyces coelicolor)	5 / 9	VAL A 70 LEU A 92 TYR A 107 LEU A 150 ASP A 151	None	0.94A	3hthB-3iuvA: 22.8	3hthB-3iuvA: 92.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LNW_A_T3A501_1 (THYROID HORMONE RECEPTOR ALPHA)	3iuv	UNCHARACTERIZED TETR FAMILY PROTEIN (Streptomyces coelicolor)	5 / 12	ILE A 13 ALA A 16 ARG A 19 LEU A 42 HIS A 31	None	1.14A	4lnwA-3iuvA: undetectable	4lnwA-3iuvA: 24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LNX_A_T3A502_1 (THYROID HORMONE RECEPTOR ALPHA)	3iuv	UNCHARACTERIZED TETR FAMILY PROTEIN (Streptomyces coelicolor)	5 / 12	ILE A 13 ALA A 16 ARG A 19 LEU A 42 HIS A 31	None	1.13A	4lnxA-3iuvA: undetectable	4lnxA-3iuvA: 24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XDR_A_ADNA402_1 (FAD:PROTEIN FMN TRANSFERASE)	3iuv	UNCHARACTERIZED TETR FAMILY PROTEIN (Streptomyces coelicolor)	5 / 12	LEU A 29 VAL A 20 ALA A 35 ILE A 13 THR A 45	None	0.87A	4xdrA-3iuvA: undetectable	4xdrA-3iuvA: 22.74

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1XZX_X_T3X500_1","THYROID HORMONE RECEPTOR BETA-1","3iuv","UNCHARACTERIZED TETR FAMILY PROTEIN","Streptomyces coelicolor",5,"ILE A  13;ALA A  16;ARG A  19;LEU A  42;HIS A  31","None","1.21A","1xzxX-3iuvA:undetectable","1xzxX-3iuvA:22.91"],["1Y0X_X_T44X500_1","THYROID HORMONE RECEPTOR BETA-1","3iuv","UNCHARACTERIZED TETR FAMILY PROTEIN","Streptomyces coelicolor",5,"ILE A  13;ALA A  16;ARG A  19;LEU A  42;HIS A  31","None","1.24A","1y0xX-3iuvA:undetectable","1y0xX-3iuvA:22.91"],["2H77_A_T3A1_1","THRA PROTEIN","3iuv","UNCHARACTERIZED TETR FAMILY PROTEIN","Streptomyces coelicolor",5,"ILE A  13;ALA A  16;ARG A  19;LEU A  42;HIS A  31","None","1.13A","2h77A-3iuvA:undetectable","2h77A-3iuvA:24.53"],["3GWW_A_SFXA801_1","TRANSPORTER","3iuv","UNCHARACTERIZED TETR FAMILY PROTEIN","Streptomyces coelicolor",5,"LEU A  92;GLY A  93;LEU A  96;ILE A 153;ASP A 165","None","1.11A","3gwwA-3iuvA:undetectable","3gwwA-3iuvA:15.68"],["3HTH_B_PRLB201_0","EBRA REPRESSOR","3iuv","UNCHARACTERIZED TETR FAMILY PROTEIN","Streptomyces coelicolor",5,"VAL A  70;LEU A  92;TYR A 107;LEU A 150;ASP A 151","None","0.94A","3hthB-3iuvA:22.8","3hthB-3iuvA:92.13"],["4LNW_A_T3A501_1","THYROID HORMONE RECEPTOR ALPHA","3iuv","UNCHARACTERIZED TETR FAMILY PROTEIN","Streptomyces coelicolor",5,"ILE A  13;ALA A  16;ARG A  19;LEU A  42;HIS A  31","None","1.14A","4lnwA-3iuvA:undetectable","4lnwA-3iuvA:24.53"],["4LNX_A_T3A502_1","THYROID HORMONE RECEPTOR ALPHA","3iuv","UNCHARACTERIZED TETR FAMILY PROTEIN","Streptomyces coelicolor",5,"ILE A  13;ALA A  16;ARG A  19;LEU A  42;HIS A  31","None","1.13A","4lnxA-3iuvA:undetectable","4lnxA-3iuvA:24.53"],["4XDR_A_ADNA402_1","FAD:PROTEIN FMN TRANSFERASE","3iuv","UNCHARACTERIZED TETR FAMILY PROTEIN","Streptomyces coelicolor",5,"LEU A  29;VAL A  20;ALA A  35;ILE A  13;THR A  45","None","0.87A","4xdrA-3iuvA:undetectable","4xdrA-3iuvA:22.74"]]