SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3iv4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 3iv4 PUTATIVE
OXIDOREDUCTASE
(Staphylococcus
aureus) 		4 / 6 ASN A  35
SER A  33
ALA A  34
HIS A  26
 None
 1.36A 3aruA-3iv4A:
undetectable		 3aruA-3iv4A:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3iv4 PUTATIVE
OXIDOREDUCTASE
(Staphylococcus
aureus) 		4 / 4 PHE A  80
VAL A  23
ALA A  79
PHE A  40
 None
 1.31A 4w5qA-3iv4A:
undetectable		 4w5qA-3iv4A:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3iv4 PUTATIVE
OXIDOREDUCTASE
(Staphylococcus
aureus) 		4 / 4 PHE A  80
VAL A  23
ALA A  79
PHE A  40
 None
 1.33A 5ki6A-3iv4A:
undetectable		 5ki6A-3iv4A:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3iv4 PUTATIVE
OXIDOREDUCTASE
(Staphylococcus
aureus) 		4 / 8 LEU A   5
VAL A  23
LYS A  25
PHE A  80
 None
 0.76A 5y9mA-3iv4A:
undetectable		 5y9mA-3iv4A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 3iv4 PUTATIVE
OXIDOREDUCTASE
(Staphylococcus
aureus) 		4 / 6 SER A  33
SER A  76
ALA A  79
ALA A  36
 None
 0.92A 6bocA-3iv4A:
undetectable
6bocB-3iv4A:
undetectable
6bocC-3iv4A:
undetectable
6bocD-3iv4A:
undetectable		 6bocA-3iv4A:
12.04
6bocB-3iv4A:
12.04
6bocC-3iv4A:
12.04
6bocD-3iv4A:
12.04