SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3iv6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		12 / 12 ASN A   5
TRP A  11
PHE A  18
PRO A  28
GLY A  50
THR A  53
PHE A  72
SER A  73
ASP A  95
ILE A  96
THR A  97
LEU A 116
 SAM  A 301 ( 4.7A)
SAM  A 301 (-3.7A)
SAM  A 301 (-3.7A)
SAM  A 301 ( 4.8A)
SAM  A 301 (-3.4A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.3A)
SAM  A 301 ( 4.7A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.5A)
SAM  A 301 ( 3.9A)
SAM  A 301 (-4.2A)
 0.00A 3iv6A-3iv6A:
48.2		 3iv6A-3iv6A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 GLY A  50
PHE A  70
ASP A  92
ILE A  91
THR A  90
 SAM  A 301 (-3.4A)
None
None
None
None
 1.18A 3iv6A-3iv6A:
48.2		 3iv6A-3iv6A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 PRO A  28
GLY A  50
ASP A  92
ILE A  91
THR A  90
 SAM  A 301 ( 4.8A)
SAM  A 301 (-3.4A)
None
None
None
 1.19A 3iv6A-3iv6A:
48.2		 3iv6A-3iv6A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 TRP A  11
PHE A  72
SER A  73
ILE A  49
LEU A 116
 SAM  A 301 (-3.7A)
SAM  A 301 (-3.3A)
SAM  A 301 ( 4.7A)
None
SAM  A 301 (-4.2A)
 1.28A 3iv6A-3iv6A:
48.2		 3iv6A-3iv6A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		3 / 3 SER A  52
ASP A  71
ASP A 114
 SAM  A 301 (-2.6A)
SAM  A 301 (-2.6A)
SAM  A 301 (-3.7A)
 0.00A 3iv6A-3iv6A:
48.2		 3iv6A-3iv6A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IV6_B_SAMB301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		12 / 12 TRP A  11
PHE A  18
GLY A  50
SER A  52
THR A  53
ASP A  71
PHE A  72
ASP A  95
ILE A  96
ASP A 114
LEU A 116
ARG A 119
 SAM  A 301 (-3.7A)
SAM  A 301 (-3.7A)
SAM  A 301 (-3.4A)
SAM  A 301 (-2.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-2.6A)
SAM  A 301 (-3.3A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.5A)
SAM  A 301 (-3.7A)
SAM  A 301 (-4.2A)
None
 0.35A 3iv6B-3iv6A:
7.2		 3iv6B-3iv6A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IV6_B_SAMB301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 TRP A  11
PHE A  18
PHE A  72
ASP A  95
ARG A 208
 SAM  A 301 (-3.7A)
SAM  A 301 (-3.7A)
SAM  A 301 (-3.3A)
SAM  A 301 (-3.6A)
None
 1.14A 3iv6B-3iv6A:
7.2		 3iv6B-3iv6A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IV6_C_SAMC301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		12 / 12 TRP A  11
PHE A  18
ARG A  27
PRO A  28
GLY A  50
THR A  53
PHE A  72
SER A  73
ASP A  95
ILE A  96
ARG A 115
LEU A 116
 SAM  A 301 (-3.7A)
SAM  A 301 (-3.7A)
None
SAM  A 301 ( 4.8A)
SAM  A 301 (-3.4A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.3A)
SAM  A 301 ( 4.7A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.5A)
None
SAM  A 301 (-4.2A)
 0.26A 3iv6C-3iv6A:
44.6		 3iv6C-3iv6A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IV6_C_SAMC301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 TRP A 204
PHE A  18
ARG A  27
PRO A  28
ARG A 115
 None
SAM  A 301 (-3.7A)
None
SAM  A 301 ( 4.8A)
None
 1.21A 3iv6C-3iv6A:
44.6		 3iv6C-3iv6A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		3 / 3 SER A  52
ASP A  71
ASP A 114
 SAM  A 301 (-2.6A)
SAM  A 301 (-2.6A)
SAM  A 301 (-3.7A)
 0.11A 3iv6C-3iv6A:
44.6		 3iv6C-3iv6A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IV6_D_SAMD301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		12 / 12 TRP A  11
GLY A  50
SER A  52
THR A  53
PHE A  72
SER A  73
ASP A  95
ILE A  96
ASP A 114
ARG A 115
LEU A 116
ARG A 119
 SAM  A 301 (-3.7A)
SAM  A 301 (-3.4A)
SAM  A 301 (-2.6A)
SAM  A 301 (-3.1A)
SAM  A 301 (-3.3A)
SAM  A 301 ( 4.7A)
SAM  A 301 (-3.6A)
SAM  A 301 (-4.5A)
SAM  A 301 (-3.7A)
None
SAM  A 301 (-4.2A)
None
 0.37A 3iv6D-3iv6A:
40.0		 3iv6D-3iv6A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IV6_D_SAMD301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 TRP A  11
PHE A  72
SER A  73
ASP A  95
ARG A 208
 SAM  A 301 (-3.7A)
SAM  A 301 (-3.3A)
SAM  A 301 ( 4.7A)
SAM  A 301 (-3.6A)
None
 1.20A 3iv6D-3iv6A:
40.0		 3iv6D-3iv6A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IV6_D_SAMD301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		7 / 12 TRP A  11
PHE A  72
SER A  73
ILE A  49
ARG A 115
LEU A 116
ARG A 119
 SAM  A 301 (-3.7A)
SAM  A 301 (-3.3A)
SAM  A 301 ( 4.7A)
None
None
SAM  A 301 (-4.2A)
None
 1.27A 3iv6D-3iv6A:
40.0		 3iv6D-3iv6A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 ILE A  14
GLY A  15
ASN A  16
THR A 200
LEU A 201
 None
 1.08A 4e3aA-3iv6A:
3.4		 4e3aA-3iv6A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 ILE A  14
GLY A  15
ASN A  16
THR A 200
LEU A 201
 None
 1.07A 4jkuB-3iv6A:
3.4		 4jkuB-3iv6A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 ILE A  14
GLY A  15
ASN A  16
THR A 200
LEU A 201
 None
 1.07A 4k8pA-3iv6A:
3.4		 4k8pA-3iv6A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 ILE A  14
GLY A  15
ASN A  16
THR A 200
LEU A 201
 None
 1.06A 4k8pB-3iv6A:
3.4		 4k8pB-3iv6A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 ILE A  14
GLY A  15
ASN A  16
THR A 200
LEU A 201
 None
 1.06A 4k8tA-3iv6A:
3.4		 4k8tA-3iv6A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 ILE A  14
GLY A  15
ASN A  16
THR A 200
LEU A 201
 None
 1.05A 4k8tB-3iv6A:
3.4		 4k8tB-3iv6A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 ILE A  14
GLY A  15
ASN A  16
THR A 200
LEU A 201
 None
 1.07A 4k93A-3iv6A:
3.7		 4k93A-3iv6A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 ILE A  14
GLY A  15
ASN A  16
THR A 200
LEU A 201
 None
 1.06A 4k93B-3iv6A:
3.4		 4k93B-3iv6A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 ILE A  14
GLY A  15
ASN A  16
THR A 200
LEU A 201
 None
 1.08A 4k9cA-3iv6A:
3.4		 4k9cA-3iv6A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 ILE A  14
GLY A  15
ASN A  16
THR A 200
LEU A 201
 None
 1.06A 4k9cB-3iv6A:
3.4		 4k9cB-3iv6A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 ILE A  14
GLY A  15
ASN A  16
THR A 200
LEU A 201
 None
 1.07A 4k9iA-3iv6A:
3.4		 4k9iA-3iv6A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 ILE A  14
GLY A  15
ASN A  16
THR A 200
LEU A 201
 None
 1.08A 4k9iB-3iv6A:
3.4		 4k9iB-3iv6A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 ILE A  14
GLY A  15
ASN A  16
THR A 200
LEU A 201
 None
 1.06A 4kadA-3iv6A:
4.1		 4kadA-3iv6A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 ILE A  14
GLY A  15
ASN A  16
THR A 200
LEU A 201
 None
 1.06A 4kadB-3iv6A:
4.0		 4kadB-3iv6A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 ILE A  14
GLY A  15
ASN A  16
THR A 200
LEU A 201
 None
 1.08A 4lbxA-3iv6A:
3.4		 4lbxA-3iv6A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 ILE A  14
GLY A  15
ASN A  16
THR A 200
LEU A 201
 None
 1.06A 4lbxB-3iv6A:
3.4		 4lbxB-3iv6A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 ILE A  14
GLY A  15
ASN A  16
THR A 200
LEU A 201
 None
 1.08A 4lc4A-3iv6A:
3.4		 4lc4A-3iv6A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 ILE A  14
GLY A  15
ASN A  16
THR A 200
LEU A 201
 None
 1.07A 4lc4B-3iv6A:
3.5		 4lc4B-3iv6A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 LEU A 202
ALA A 189
GLY A 183
ALA A 182
ILE A 152
 None
 0.91A 4nkxA-3iv6A:
undetectable		 4nkxA-3iv6A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 LEU A 202
ALA A 189
GLY A 183
ALA A 182
ILE A 152
 None
 0.89A 4nkxB-3iv6A:
undetectable		 4nkxB-3iv6A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 LEU A 202
ALA A 189
GLY A 183
ALA A 182
ILE A 152
 None
 0.94A 4nkxC-3iv6A:
undetectable		 4nkxC-3iv6A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		3 / 3 ASP A 187
GLU A 203
SER A 163
 None
 0.75A 5bw4B-3iv6A:
0.8		 5bw4B-3iv6A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		3 / 3 THR A 122
THR A 121
PHE A 177
 None
 0.87A 5cxvA-3iv6A:
undetectable		 5cxvA-3iv6A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		3 / 3 TRP A  11
ARG A 119
LEU A 201
 SAM  A 301 (-3.7A)
None
None
 0.88A 5dbyA-3iv6A:
undetectable		 5dbyA-3iv6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V1T_A_SAMA605_0
(RADICAL SAM)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 LEU A 112
VAL A 136
ARG A 256
THR A 248
GLU A 237
 None
 1.46A 5v1tA-3iv6A:
undetectable		 5v1tA-3iv6A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA715_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		4 / 6 GLY A 137
SER A 254
ARG A 255
ARG A 256
 None
 0.98A 6dwdA-3iv6A:
undetectable
6dwdC-3iv6A:
undetectable		 6dwdA-3iv6A:
18.98
6dwdC-3iv6A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J21_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 3iv6 PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 ILE A  49
VAL A  69
ILE A 117
VAL A 111
PHE A  36
 None
 1.31A 6j21A-3iv6A:
undetectable		 6j21A-3iv6A:
20.73