SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ive'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 3ive NUCLEOTIDASE
(Escherichia
coli) 		4 / 7 THR A 463
THR A 475
GLY A 471
ASP A 472
 None
None
None
CTN  A 603 (-2.7A)
 0.94A 1bu5A-3iveA:
undetectable		 1bu5A-3iveA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		6 / 11 GLY A 372
ARG A 375
PHE A 394
ASN A 396
PHE A 466
ASP A 472
 CTN  A 603 (-3.2A)
CTN  A 603 ( 3.0A)
CTN  A 603 (-3.5A)
CTN  A 603 (-3.0A)
CTN  A 603 (-3.8A)
CTN  A 603 (-2.7A)
 0.65A 1ho5A-3iveA:
37.3		 1ho5A-3iveA:
28.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_B_ADNB2604_1
(5'-NUCLEOTIDASE)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		6 / 10 GLY A 372
ARG A 375
PHE A 394
ASN A 396
PHE A 466
ASP A 472
 CTN  A 603 (-3.2A)
CTN  A 603 ( 3.0A)
CTN  A 603 (-3.5A)
CTN  A 603 (-3.0A)
CTN  A 603 (-3.8A)
CTN  A 603 (-2.7A)
 0.51A 1ho5B-3iveA:
37.3		 1ho5B-3iveA:
28.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		3 / 3 ASP A  79
HIS A 112
HIS A  34
 FE  A 602 (-2.6A)
CTN  A 603 ( 3.8A)
MN  A 601 ( 3.4A)
 0.68A 1oe1A-3iveA:
undetectable		 1oe1A-3iveA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		3 / 3 ASP A  79
HIS A 112
HIS A  34
 FE  A 602 (-2.6A)
CTN  A 603 ( 3.8A)
MN  A 601 ( 3.4A)
 0.67A 1oe3A-3iveA:
undetectable		 1oe3A-3iveA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 10 SER A 417
GLY A 421
VAL A 422
GLU A 413
SER A 419
 None
 1.46A 1pk7C-3iveA:
undetectable		 1pk7C-3iveA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 10 LEU A  89
VAL A 327
GLY A 386
VAL A 496
VAL A 331
 None
 1.40A 2cp4A-3iveA:
undetectable		 2cp4A-3iveA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ECP_A_ACRA992_1
(MALTODEXTRIN
PHOSPHORYLASE)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 10 TYR A 342
ARG A 229
ASP A 472
ARG A 375
HIS A  34
 None
None
CTN  A 603 (-2.7A)
CTN  A 603 ( 3.0A)
MN  A 601 ( 3.4A)
 1.49A 2ecpA-3iveA:
undetectable		 2ecpA-3iveA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_A_PPFA3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 3ive NUCLEOTIDASE
(Escherichia
coli) 		4 / 8 HIS A 116
SER A  87
ASP A 115
ALA A  35
 None
None
CTN  A 603 ( 4.1A)
None
 1.38A 2rk8A-3iveA:
undetectable		 2rk8A-3iveA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		3 / 3 ASP A  79
HIS A 112
HIS A  34
 FE  A 602 (-2.6A)
CTN  A 603 ( 3.8A)
MN  A 601 ( 3.4A)
 0.69A 2xxgA-3iveA:
undetectable		 2xxgA-3iveA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		3 / 3 ASP A  79
HIS A 112
HIS A  34
 FE  A 602 (-2.6A)
CTN  A 603 ( 3.8A)
MN  A 601 ( 3.4A)
 0.70A 2xxgC-3iveA:
undetectable		 2xxgC-3iveA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 12 ALA A 352
THR A 391
ASN A 370
GLY A 372
LEU A 467
 None
None
CTN  A 603 (-3.2A)
CTN  A 603 (-3.2A)
None
 1.44A 3aodC-3iveA:
undetectable		 3aodC-3iveA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHT_A_SAMA200_0
(S-ADENOSYL-L-METHION
INE METHYL
TRANSFERASE)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 12 GLY A 135
THR A 108
ASP A 198
ILE A 197
LEU A 193
 None
 0.90A 3ihtA-3iveA:
undetectable		 3ihtA-3iveA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		3 / 3 ASN A 396
ASP A 115
ARG A 229
 CTN  A 603 (-3.0A)
CTN  A 603 ( 4.1A)
None
 0.60A 3k13A-3iveA:
undetectable		 3k13A-3iveA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		3 / 3 ASN A 396
ASP A 115
ARG A 229
 CTN  A 603 (-3.0A)
CTN  A 603 ( 4.1A)
None
 0.85A 3k13C-3iveA:
undetectable		 3k13C-3iveA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		4 / 8 SER A 177
ASN A 396
PHE A 466
ASP A 469
 CTN  A 603 (-4.2A)
CTN  A 603 (-3.0A)
CTN  A 603 (-3.8A)
None
 1.23A 3n62A-3iveA:
undetectable		 3n62A-3iveA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_B_KKKB413_1
(FLAVOHEMOGLOBIN)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 12 ILE A 374
GLN A 424
ALA A 353
LEU A 338
ILE A 461
 None
 1.12A 3ozwB-3iveA:
undetectable		 3ozwB-3iveA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA2_1
(CYTOCHROME P450 2D6)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 11 LEU A 446
GLU A 413
LEU A 368
PHE A 477
PHE A 474
 None
 1.30A 3tbgA-3iveA:
undetectable		 3tbgA-3iveA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		4 / 7 ASP A 115
PHE A 114
GLY A 110
THR A  82
 CTN  A 603 ( 4.1A)
None
None
None
 1.13A 3vnsA-3iveA:
undetectable		 3vnsA-3iveA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		6 / 9 ASN A 370
GLY A 372
GLY A 373
PHE A 394
ASN A 396
ASP A 472
 CTN  A 603 (-3.2A)
CTN  A 603 (-3.2A)
CTN  A 603 (-3.3A)
CTN  A 603 (-3.5A)
CTN  A 603 (-3.0A)
CTN  A 603 (-2.7A)
 0.61A 3ztvA-3iveA:
33.3		 3ztvA-3iveA:
28.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 12 ILE A 109
GLY A  78
ASP A  79
ASP A 115
ASN A 120
 None
None
FE  A 602 (-2.6A)
CTN  A 603 ( 4.1A)
None
 0.92A 4a81A-3iveA:
undetectable		 4a81A-3iveA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		4 / 5 ILE A 453
ILE A 461
TYR A 459
GLU A 402
 None
 1.13A 4a99D-3iveA:
undetectable		 4a99D-3iveA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		4 / 8 TRP A  55
HIS A  36
GLU A  38
ILE A  98
 None
 1.20A 4cx7A-3iveA:
undetectable
4cx7B-3iveA:
undetectable		 4cx7A-3iveA:
24.64
4cx7B-3iveA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 11 ILE A 248
ALA A  77
GLY A  78
GLY A 135
ASN A 136
 None
 1.30A 4e47B-3iveA:
undetectable		 4e47B-3iveA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA302_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		4 / 5 HIS A 112
TYR A 342
GLN A 219
GLY A 372
 CTN  A 603 ( 3.8A)
None
None
CTN  A 603 (-3.2A)
 1.28A 4fu8A-3iveA:
undetectable		 4fu8A-3iveA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H2F_A_ADNA601_1
(5'-NUCLEOTIDASE)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		7 / 9 ASN A 370
GLY A 372
GLY A 373
ARG A 375
PHE A 394
PHE A 466
ASP A 472
 CTN  A 603 (-3.2A)
CTN  A 603 (-3.2A)
CTN  A 603 (-3.3A)
CTN  A 603 ( 3.0A)
CTN  A 603 (-3.5A)
CTN  A 603 (-3.8A)
CTN  A 603 (-2.7A)
 0.39A 4h2fA-3iveA:
35.0		 4h2fA-3iveA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H2G_A_ADNA603_1
(5'-NUCLEOTIDASE)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		7 / 9 ASN A 370
GLY A 372
GLY A 373
ARG A 375
PHE A 394
PHE A 466
ASP A 472
 CTN  A 603 (-3.2A)
CTN  A 603 (-3.2A)
CTN  A 603 (-3.3A)
CTN  A 603 ( 3.0A)
CTN  A 603 (-3.5A)
CTN  A 603 (-3.8A)
CTN  A 603 (-2.7A)
 0.54A 4h2gA-3iveA:
34.8		 4h2gA-3iveA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 12 PHE A 172
GLY A 110
LEU A  33
ALA A  35
HIS A 253
 None
None
None
None
MN  A 601 ( 3.5A)
 1.12A 4krhB-3iveA:
undetectable		 4krhB-3iveA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM9_A_FVXA603_1
(TRANSPORTER)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 11 ALA A 352
TYR A 498
GLY A 512
SER A 347
GLY A 349
 None
 1.30A 4mm9A-3iveA:
undetectable		 4mm9A-3iveA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 12 ASP A 245
LEU A 166
GLY A 243
ALA A 209
GLY A 263
 None
 1.13A 4n09A-3iveA:
undetectable		 4n09A-3iveA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 12 GLY A 373
GLY A 372
ASN A 370
ALA A 217
GLY A 471
 CTN  A 603 (-3.3A)
CTN  A 603 (-3.2A)
CTN  A 603 (-3.2A)
SO4  A 604 (-3.7A)
None
 1.02A 4n09B-3iveA:
undetectable		 4n09B-3iveA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 12 GLY A 373
GLY A 372
ASN A 370
GLY A 471
ASP A 472
 CTN  A 603 (-3.3A)
CTN  A 603 (-3.2A)
CTN  A 603 (-3.2A)
None
CTN  A 603 (-2.7A)
 0.98A 4n09B-3iveA:
undetectable		 4n09B-3iveA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 12 GLY A 373
GLY A 372
ASN A 370
GLY A 471
ASP A 472
 CTN  A 603 (-3.3A)
CTN  A 603 (-3.2A)
CTN  A 603 (-3.2A)
None
CTN  A 603 (-2.7A)
 0.98A 4n09D-3iveA:
undetectable		 4n09D-3iveA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		4 / 5 ASN A  57
ALA A 303
GLY A  53
ASP A 324
 None
 0.99A 4n48A-3iveA:
undetectable		 4n48A-3iveA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		3 / 3 SER A 334
ALA A 332
VAL A 331
 None
 0.69A 4o2bC-3iveA:
undetectable		 4o2bC-3iveA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_A_ADNA1002_1
(MYOSIN HEAVY CHAIN
KINASE A)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 11 PHE A 499
ALA A 332
VAL A 495
LEU A 348
THR A 391
 None
 1.18A 4zmeA-3iveA:
undetectable		 4zmeA-3iveA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_B_ADNB902_1
(MYOSIN HEAVY CHAIN
KINASE A)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 10 PHE A 499
ALA A 332
VAL A 495
LEU A 348
THR A 391
 None
 1.18A 4zmeB-3iveA:
undetectable		 4zmeB-3iveA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		3 / 3 GLU A 337
TRP A  44
ASN A 376
 None
 1.05A 5dv4A-3iveA:
5.1		 5dv4A-3iveA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_A_SHHA2004_1
(HDAC6 PROTEIN)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 12 PRO A 395
SER A  87
HIS A  34
GLY A  83
HIS A 112
 None
None
MN  A 601 ( 3.4A)
None
CTN  A 603 ( 3.8A)
 1.35A 5eeiA-3iveA:
undetectable		 5eeiA-3iveA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_B_SHHB801_1
(HDAC6 PROTEIN)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 12 PRO A 395
SER A  87
HIS A  34
GLY A  83
HIS A 112
 None
None
MN  A 601 ( 3.4A)
None
CTN  A 603 ( 3.8A)
 1.35A 5eeiB-3iveA:
undetectable		 5eeiB-3iveA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 11 ARG A 375
GLY A  92
HIS A 116
ALA A  35
ILE A  95
 CTN  A 603 ( 3.0A)
None
None
None
None
 1.21A 5eexI-3iveA:
undetectable
5eexJ-3iveA:
undetectable		 5eexI-3iveA:
10.77
5eexJ-3iveA:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 11 ARG A 375
GLY A  92
HIS A 116
ALA A  35
ILE A  95
 CTN  A 603 ( 3.0A)
None
None
None
None
 1.21A 5eeyI-3iveA:
undetectable
5eeyJ-3iveA:
undetectable		 5eeyI-3iveA:
10.77
5eeyJ-3iveA:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 11 ARG A 375
GLY A  92
HIS A 116
ALA A  35
ILE A  95
 CTN  A 603 ( 3.0A)
None
None
None
None
 1.21A 5eezI-3iveA:
undetectable
5eezJ-3iveA:
undetectable		 5eezI-3iveA:
10.77
5eezJ-3iveA:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 11 ARG A 375
GLY A  92
HIS A 116
ALA A  35
ILE A  95
 CTN  A 603 ( 3.0A)
None
None
None
None
 1.21A 5ef0I-3iveA:
undetectable
5ef0J-3iveA:
undetectable		 5ef0I-3iveA:
10.77
5ef0J-3iveA:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 11 ARG A 375
GLY A  92
HIS A 116
ALA A  35
ILE A  95
 CTN  A 603 ( 3.0A)
None
None
None
None
 1.21A 5ef1I-3iveA:
undetectable
5ef1J-3iveA:
undetectable		 5ef1I-3iveA:
10.77
5ef1J-3iveA:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 11 ARG A 375
GLY A  92
HIS A 116
ALA A  35
ILE A  95
 CTN  A 603 ( 3.0A)
None
None
None
None
 1.21A 5ef2I-3iveA:
undetectable
5ef2J-3iveA:
undetectable		 5ef2I-3iveA:
10.77
5ef2J-3iveA:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 11 ARG A 375
GLY A  92
HIS A 116
ALA A  35
ILE A  95
 CTN  A 603 ( 3.0A)
None
None
None
None
 1.21A 5ef3I-3iveA:
undetectable
5ef3J-3iveA:
undetectable		 5ef3I-3iveA:
10.77
5ef3J-3iveA:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9H_R_ADNR400_1
(CHIMERA PROTEIN OF
MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4 AND
ADENOSINE RECEPTOR
A1)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 10 VAL A 241
THR A 237
LEU A 166
ASN A 136
ILE A 164
 None
 1.39A 6d9hR-3iveA:
undetectable		 6d9hR-3iveA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		5 / 12 ALA A 358
LEU A 356
PHE A 474
LEU A 351
TYR A 498
 None
 1.04A 6djzC-3iveA:
undetectable		 6djzC-3iveA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 3ive NUCLEOTIDASE
(Escherichia
coli) 		4 / 8 GLY A 473
THR A 475
SER A 419
PHE A 170
 None
 1.10A 6eqpA-3iveA:
undetectable		 6eqpA-3iveA:
10.22