SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ivf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 3ivf TALIN-1
(Mus
musculus) 		5 / 12 LEU A  68
PHE A  19
LEU A  62
ILE A  32
ILE A   8
 None
 1.02A 2bxqA-3ivfA:
2.3		 2bxqA-3ivfA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 3ivf TALIN-1
(Mus
musculus) 		4 / 7 SER A 379
ALA A 360
SER A 365
THR A 367
 None
 0.75A 3cfqA-3ivfA:
undetectable
3cfqB-3ivfA:
undetectable		 3cfqA-3ivfA:
15.28
3cfqB-3ivfA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ivf TALIN-1
(Mus
musculus) 		4 / 5 VAL A 130
LEU A 129
SER A 128
MET A  92
 None
 1.37A 4e1gA-3ivfA:
undetectable		 4e1gA-3ivfA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 3ivf TALIN-1
(Mus
musculus) 		4 / 7 ALA A 360
SER A 365
THR A 367
SER A 379
 None
 0.73A 4ikjA-3ivfA:
undetectable
4ikjB-3ivfA:
undetectable		 4ikjA-3ivfA:
15.01
4ikjB-3ivfA:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 3ivf TALIN-1
(Mus
musculus) 		4 / 7 SER A 379
ALA A 360
SER A 365
THR A 367
 None
 0.71A 4ikkA-3ivfA:
undetectable
4ikkB-3ivfA:
undetectable		 4ikkA-3ivfA:
15.01
4ikkB-3ivfA:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 3ivf TALIN-1
(Mus
musculus) 		4 / 7 ALA A 360
SER A 365
THR A 367
SER A 379
 None
 0.68A 4iklA-3ivfA:
undetectable
4iklB-3ivfA:
undetectable		 4iklA-3ivfA:
15.01
4iklB-3ivfA:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 3ivf TALIN-1
(Mus
musculus) 		4 / 8 SER A 379
ALA A 360
SER A 365
THR A 367
 None
 0.68A 4iklA-3ivfA:
undetectable
4iklB-3ivfA:
undetectable		 4iklA-3ivfA:
15.01
4iklB-3ivfA:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WH5_A_3QBA204_1
(LINCOSAMIDE
RESISTANCE PROTEIN)		 3ivf TALIN-1
(Mus
musculus) 		5 / 12 GLY A 287
ALA A 294
GLN A 244
PHE A 241
HIS A 283
 None
 1.30A 4wh5A-3ivfA:
undetectable		 4wh5A-3ivfA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)		 3ivf TALIN-1
(Mus
musculus) 		3 / 3 PRO A 327
ARG A 328
GLU A 342
 None
 0.90A 5j6hA-3ivfA:
undetectable		 5j6hA-3ivfA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS5_A_ASCA202_0
(CYTOCHROME C')		 3ivf TALIN-1
(Mus
musculus) 		3 / 3 CYH A 286
LYS A 284
HIS A 250
 None
 1.16A 5js5A-3ivfA:
undetectable		 5js5A-3ivfA:
14.82