SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ivp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 3ivp PUTATIVE
TRANSPOSON-RELATED
DNA-BINDING PROTEIN
(Clostridioides
difficile) 		4 / 5 GLY A  25
LEU A  26
THR A  27
ARG A  21
 None
 1.11A 1ekjF-3ivpA:
undetectable
1ekjG-3ivpA:
undetectable		 1ekjF-3ivpA:
22.97
1ekjG-3ivpA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 3ivp PUTATIVE
TRANSPOSON-RELATED
DNA-BINDING PROTEIN
(Clostridioides
difficile) 		5 / 10 LEU A  60
LEU A  64
ILE A  35
GLU A  29
LEU A  26
 None
 1.20A 1wopA-3ivpA:
undetectable		 1wopA-3ivpA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_B_ADNB501_1
(HYPOTHETICAL PROTEIN
PH0463)		 3ivp PUTATIVE
TRANSPOSON-RELATED
DNA-BINDING PROTEIN
(Clostridioides
difficile) 		5 / 11 ARG A  21
ILE A  37
ASP A  38
PRO A  39
ASN A  47
 None
 1.26A 1wu8B-3ivpA:
undetectable
1wu8C-3ivpA:
undetectable		 1wu8B-3ivpA:
19.92
1wu8C-3ivpA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)		 3ivp PUTATIVE
TRANSPOSON-RELATED
DNA-BINDING PROTEIN
(Clostridioides
difficile) 		5 / 11 ILE A  17
GLY A  49
HIS A  51
LEU A  57
GLY A  14
 None
 1.29A 2fn1A-3ivpA:
undetectable		 2fn1A-3ivpA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 3ivp PUTATIVE
TRANSPOSON-RELATED
DNA-BINDING PROTEIN
(Clostridioides
difficile) 		5 / 12 ASP A  59
LEU A  60
SER A  62
LEU A  42
ILE A  37
 None
 1.04A 4x1fA-3ivpA:
undetectable		 4x1fA-3ivpA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1G_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 3ivp PUTATIVE
TRANSPOSON-RELATED
DNA-BINDING PROTEIN
(Clostridioides
difficile) 		5 / 12 ASP A  59
LEU A  60
SER A  62
LEU A  42
ILE A  37
 None
 1.03A 4x1gA-3ivpA:
undetectable		 4x1gA-3ivpA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 3ivp PUTATIVE
TRANSPOSON-RELATED
DNA-BINDING PROTEIN
(Clostridioides
difficile) 		3 / 3 THR A  95
ASP A  96
ALA A  97
 None
 0.09A 5g5gB-3ivpA:
undetectable		 5g5gB-3ivpA:
17.35