SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3iwf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UBS_A_DIFA503_1 (PENTALENIC ACID SYNTHASE)	3iwf	TRANSCRIPTION REGULATOR RPIR FAMILY (Staphylococcus epidermidis)	4 / 7	LEU A 71 ALA A 23 LEU A 27 ILE A 22	None	0.82A	4ubsA-3iwfA: undetectable	4ubsA-3iwfA: 12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y7P_D_CHDD401_0 (BILE SALT HYDROLASE)	3iwf	TRANSCRIPTION REGULATOR RPIR FAMILY (Staphylococcus epidermidis)	5 / 10	ILE A 52 LEU A 55 PHE A 64 LEU A 27 LEU A 71	None	1.28A	5y7pD-3iwfA: undetectable	5y7pD-3iwfA: 16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YW0_A_ACTA412_0 (UNCHARACTERIZED PROTEIN KDOO)	3iwf	TRANSCRIPTION REGULATOR RPIR FAMILY (Staphylococcus epidermidis)	3 / 3	LYS A 21 ASN A 18 SER A 51	None	1.05A	5yw0A-3iwfA: undetectable	5yw0A-3iwfA: 17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HLP_A_GAWA1501_0 (SUBSTANCE-P RECEPTOR,SUBSTANCE-P RECEPTOR)	3iwf	TRANSCRIPTION REGULATOR RPIR FAMILY (Staphylococcus epidermidis)	5 / 12	ILE A 8 VAL A 59 THR A 60 ILE A 4 PHE A 64	None	1.14A	6hlpA-3iwfA: undetectable	6hlpA-3iwfA: 13.65

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4UBS_A_DIFA503_1","PENTALENIC ACID SYNTHASE","3iwf","TRANSCRIPTION REGULATOR RPIR FAMILY","Staphylococcus epidermidis",4,"LEU A  71;ALA A  23;LEU A  27;ILE A  22","None","0.82A","4ubsA-3iwfA:undetectable","4ubsA-3iwfA:12.14"],["5Y7P_D_CHDD401_0","BILE SALT HYDROLASE","3iwf","TRANSCRIPTION REGULATOR RPIR FAMILY","Staphylococcus epidermidis",5,"ILE A  52;LEU A  55;PHE A  64;LEU A  27;LEU A  71","None","1.28A","5y7pD-3iwfA:undetectable","5y7pD-3iwfA:16.92"],["5YW0_A_ACTA412_0","UNCHARACTERIZED PROTEIN KDOO","3iwf","TRANSCRIPTION REGULATOR RPIR FAMILY","Staphylococcus epidermidis",3,"LYS A  21;ASN A  18;SER A  51","None","1.05A","5yw0A-3iwfA:undetectable","5yw0A-3iwfA:17.04"],["6HLP_A_GAWA1501_0","SUBSTANCE-P RECEPTOR,SUBSTANCE-P RECEPTOR","3iwf","TRANSCRIPTION REGULATOR RPIR FAMILY","Staphylococcus epidermidis",5,"ILE A   8;VAL A  59;THR A  60;ILE A   4;PHE A  64","None","1.14A","6hlpA-3iwfA:undetectable","6hlpA-3iwfA:13.65"]]