SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3iwj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 10 GLY A 363
ALA A 352
THR A 378
ILE A 359
GLY A 396
 None
 0.95A 1c9sN-3iwjA:
undetectable
1c9sO-3iwjA:
undetectable		 1c9sN-3iwjA:
10.54
1c9sO-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 11 GLY A 363
ALA A 352
THR A 378
ILE A 359
GLY A 396
 None
 0.96A 1c9sP-3iwjA:
undetectable
1c9sQ-3iwjA:
undetectable		 1c9sP-3iwjA:
10.54
1c9sQ-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 9 GLY A 363
ALA A 352
THR A 378
ILE A 359
GLY A 396
 None
 0.93A 1c9sQ-3iwjA:
undetectable
1c9sR-3iwjA:
undetectable		 1c9sQ-3iwjA:
10.54
1c9sR-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 10 GLY A 396
GLY A 363
ALA A 352
THR A 378
ILE A 359
 None
 0.93A 1c9sL-3iwjA:
undetectable
1c9sV-3iwjA:
undetectable		 1c9sL-3iwjA:
10.54
1c9sV-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 9 GLY A 396
GLY A 363
ALA A 352
THR A 378
ILE A 359
 None
 0.89A 1gtfD-3iwjA:
undetectable
1gtfE-3iwjA:
undetectable		 1gtfD-3iwjA:
10.54
1gtfE-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 10 GLY A 396
GLY A 363
ALA A 352
THR A 378
ILE A 359
 None
 0.89A 1gtfJ-3iwjA:
undetectable
1gtfK-3iwjA:
undetectable		 1gtfJ-3iwjA:
10.54
1gtfK-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 11 GLY A 363
ALA A 352
THR A 378
ILE A 359
GLY A 396
 None
 0.95A 1gtfQ-3iwjA:
undetectable
1gtfR-3iwjA:
undetectable		 1gtfQ-3iwjA:
10.54
1gtfR-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 9 GLY A 363
ALA A 352
THR A 378
ILE A 359
GLY A 396
 None
 0.95A 1gtfR-3iwjA:
undetectable
1gtfS-3iwjA:
undetectable		 1gtfR-3iwjA:
10.54
1gtfS-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 11 GLY A 363
ALA A 352
THR A 378
ILE A 359
GLY A 396
 None
 0.94A 1gtfS-3iwjA:
undetectable
1gtfT-3iwjA:
undetectable		 1gtfS-3iwjA:
10.54
1gtfT-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 11 GLY A 363
ALA A 352
THR A 378
ILE A 359
GLY A 396
 None
 0.93A 1gtnT-3iwjA:
undetectable
1gtnU-3iwjA:
undetectable		 1gtnT-3iwjA:
10.54
1gtnU-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 12 GLY A 396
GLY A 363
ALA A 352
THR A 378
ILE A 359
 None
 0.93A 1gtnL-3iwjA:
undetectable
1gtnV-3iwjA:
undetectable		 1gtnL-3iwjA:
10.54
1gtnV-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 12 LEU A 311
LEU A 275
ALA A 278
ILE A 426
LEU A 399
 None
 1.05A 1tw4A-3iwjA:
undetectable		 1tw4A-3iwjA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 10 GLY A 363
ALA A 352
THR A 378
ILE A 359
GLY A 396
 None
 0.91A 1utdE-3iwjA:
undetectable
1utdF-3iwjA:
undetectable		 1utdE-3iwjA:
10.54
1utdF-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 10 GLY A 363
ALA A 352
THR A 378
ILE A 359
GLY A 396
 None
 0.87A 1utdH-3iwjA:
undetectable
1utdI-3iwjA:
undetectable		 1utdH-3iwjA:
10.54
1utdI-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 12 GLY A 363
ALA A 352
THR A 378
ILE A 359
GLY A 396
 None
 0.95A 1utdL-3iwjA:
undetectable
1utdM-3iwjA:
undetectable		 1utdL-3iwjA:
10.54
1utdM-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 12 GLY A 363
ALA A 352
THR A 378
ILE A 359
GLY A 396
 None
 0.93A 1utdO-3iwjA:
undetectable
1utdP-3iwjA:
undetectable		 1utdO-3iwjA:
10.54
1utdP-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 11 GLY A 363
ALA A 352
THR A 378
ILE A 359
GLY A 396
 None
 0.91A 1utdP-3iwjA:
undetectable
1utdQ-3iwjA:
undetectable		 1utdP-3iwjA:
10.54
1utdQ-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 11 GLY A 363
ALA A 352
THR A 378
ILE A 359
GLY A 396
 None
 0.92A 1utdS-3iwjA:
undetectable
1utdT-3iwjA:
undetectable		 1utdS-3iwjA:
10.54
1utdT-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 10 GLY A 363
ALA A 352
THR A 378
ILE A 359
GLY A 396
 None
 0.95A 1utdU-3iwjA:
undetectable
1utdV-3iwjA:
undetectable		 1utdU-3iwjA:
10.54
1utdV-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 11 GLY A 396
GLY A 363
ALA A 352
THR A 378
ILE A 359
 None
 0.93A 1utdL-3iwjA:
undetectable
1utdV-3iwjA:
undetectable		 1utdL-3iwjA:
10.54
1utdV-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_A_SAMA201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 12 GLY A 179
ALA A 178
LEU A 211
VAL A  51
LEU A 225
 None
 0.96A 2nyuA-3iwjA:
2.7		 2nyuA-3iwjA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 12 THR A 159
GLY A 222
LEU A 225
LEU A  10
GLU A 188
 None
NAD  A 504 (-3.8A)
None
None
NAD  A 504 (-3.1A)
 1.21A 2zw9B-3iwjA:
2.1		 2zw9B-3iwjA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_2
(PHOSPHOLIPASE A2)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 9 VAL A 336
GLY A 101
LYS A 102
PRO A 326
GLY A 372
 None
 1.42A 3bjwG-3iwjA:
undetectable		 3bjwG-3iwjA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		6 / 11 ALA A  57
THR A  56
VAL A 210
ALA A  64
GLY A  63
ALA A  67
 None
 1.30A 3mg0K-3iwjA:
undetectable
3mg0L-3iwjA:
undetectable		 3mg0K-3iwjA:
19.24
3mg0L-3iwjA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		4 / 6 THR A 289
ASN A 290
CYH A 100
GLY A 101
 None
 1.28A 3w9tE-3iwjA:
undetectable		 3w9tE-3iwjA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1000_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		4 / 6 GLU A  87
PRO A  90
LYS A  88
GLU A  91
 None
 1.18A 4a7tA-3iwjA:
undetectable		 4a7tA-3iwjA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_F_5FWF1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		4 / 6 GLU A  87
PRO A  90
LYS A  88
GLU A  91
 None
 1.17A 4a7tF-3iwjA:
undetectable		 4a7tF-3iwjA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7U_A_ALEA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		4 / 6 GLU A  87
PRO A  90
LYS A  88
GLU A  91
 None
 1.18A 4a7uA-3iwjA:
undetectable		 4a7uA-3iwjA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 11 GLY A 372
PRO A 397
ILE A 345
LEU A 346
ILE A 375
 None
 1.00A 4dt8A-3iwjA:
undetectable		 4dt8A-3iwjA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 10 GLY A 372
PRO A 397
ILE A 345
LEU A 346
ILE A 375
 None
 0.97A 4dt8B-3iwjA:
undetectable		 4dt8B-3iwjA:
19.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FR8_A_TNGA601_1
(ALDEHYDE
DEHYDROGENASE,
MITOCHONDRIAL)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		6 / 11 ASN A 162
LEU A 166
MET A 167
TRP A 170
CYH A 294
SER A 295
 GOL  A 507 (-4.4A)
None
GOL  A 507 ( 4.0A)
None
GOL  A 507 (-3.4A)
GOL  A 507 ( 3.7A)
 0.47A 4fr8A-3iwjA:
58.3		 4fr8A-3iwjA:
40.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		3 / 3 ALA A 457
GLN A 451
GLY A 285
 None
 0.55A 4odoC-3iwjA:
undetectable		 4odoC-3iwjA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		3 / 3 GLY A 334
PRO A 335
GLN A 292
 None
 0.47A 4oltB-3iwjA:
undetectable		 4oltB-3iwjA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		3 / 3 GLY A 334
PRO A 335
GLN A 292
 None
 0.45A 4qwpB-3iwjA:
undetectable		 4qwpB-3iwjA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YBN_A_ACTA303_0
(FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		3 / 3 VAL A 204
TYR A  77
ALA A  80
 None
 0.55A 4ybnA-3iwjA:
undetectable		 4ybnA-3iwjA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 12 GLY A  71
ALA A  75
ALA A 173
LEU A 476
ALA A 130
 None
 1.25A 5bw4B-3iwjA:
4.2		 5bw4B-3iwjA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 12 PRO A 207
GLY A  14
GLY A 209
LEU A 211
LEU A 195
 None
 1.06A 5c0oH-3iwjA:
4.0		 5c0oH-3iwjA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_1_BEZ1801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		3 / 3 LEU A 267
PHE A 440
ILE A 301
 None
 0.56A 5dzk1-3iwjA:
undetectable
5dzkF-3iwjA:
undetectable
5dzkM-3iwjA:
undetectable		 5dzk1-3iwjA:
0.40
5dzkF-3iwjA:
19.37
5dzkM-3iwjA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		4 / 6 ALA A 168
THR A 169
VAL A 172
VAL A  85
 None
 1.01A 5eckA-3iwjA:
undetectable		 5eckA-3iwjA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		4 / 6 ALA A 168
THR A 169
VAL A 172
VAL A  85
 None
 1.00A 5eckD-3iwjA:
undetectable		 5eckD-3iwjA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		4 / 6 ALA A 168
THR A 169
VAL A 172
VAL A  85
 None
 0.87A 5eclA-3iwjA:
undetectable		 5eclA-3iwjA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 10 GLY A 396
GLY A 363
ALA A 352
THR A 378
ILE A 359
 None
 0.91A 5eevA-3iwjA:
undetectable
5eevB-3iwjA:
undetectable		 5eevA-3iwjA:
10.54
5eevB-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 10 GLY A 396
GLY A 363
ALA A 352
THR A 378
ILE A 359
 None
 0.91A 5eewA-3iwjA:
undetectable
5eewB-3iwjA:
undetectable		 5eewA-3iwjA:
10.54
5eewB-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 10 GLY A 396
GLY A 363
ALA A 352
THR A 378
ILE A 359
 None
 0.91A 5eexA-3iwjA:
undetectable
5eexB-3iwjA:
undetectable		 5eexA-3iwjA:
10.54
5eexB-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 10 GLY A 396
GLY A 363
ALA A 352
THR A 378
ILE A 359
 None
 0.91A 5eeyA-3iwjA:
undetectable
5eeyB-3iwjA:
undetectable		 5eeyA-3iwjA:
10.54
5eeyB-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 10 GLY A 396
GLY A 363
ALA A 352
THR A 378
ILE A 359
 None
 0.91A 5eezA-3iwjA:
undetectable
5eezB-3iwjA:
undetectable		 5eezA-3iwjA:
10.54
5eezB-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 10 GLY A 396
GLY A 363
ALA A 352
THR A 378
ILE A 359
 None
 0.91A 5ef0A-3iwjA:
undetectable
5ef0B-3iwjA:
undetectable		 5ef0A-3iwjA:
10.54
5ef0B-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 10 GLY A 396
GLY A 363
ALA A 352
THR A 378
ILE A 359
 None
 0.92A 5ef1A-3iwjA:
undetectable
5ef1B-3iwjA:
undetectable		 5ef1A-3iwjA:
10.54
5ef1B-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 10 GLY A 396
GLY A 363
ALA A 352
THR A 378
ILE A 359
 None
 0.92A 5ef2A-3iwjA:
undetectable
5ef2B-3iwjA:
undetectable		 5ef2A-3iwjA:
10.54
5ef2B-3iwjA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 10 GLY A 396
GLY A 363
ALA A 352
THR A 378
ILE A 359
 None
 0.92A 5ef3A-3iwjA:
undetectable
5ef3B-3iwjA:
undetectable		 5ef3A-3iwjA:
10.54
5ef3B-3iwjA:
10.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FHZ_A_REAA602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 12 ASN A 162
LEU A 166
MET A 167
TRP A 170
CYH A 294
 GOL  A 507 (-4.4A)
None
GOL  A 507 ( 4.0A)
None
GOL  A 507 (-3.4A)
 0.89A 5fhzA-3iwjA:
56.1		 5fhzA-3iwjA:
40.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FHZ_A_REAA602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 12 THR A 455
ASN A 162
LEU A 166
MET A 167
TRP A 170
 None
GOL  A 507 (-4.4A)
None
GOL  A 507 ( 4.0A)
None
 1.45A 5fhzA-3iwjA:
56.1		 5fhzA-3iwjA:
40.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 12 VAL A 155
ASP A 232
LEU A 206
ALA A 175
PRO A 151
 None
 1.07A 5hnzB-3iwjA:
undetectable		 5hnzB-3iwjA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 12 LEU A 124
ASP A 129
GLY A  71
LEU A  78
ALA A 173
 None
 1.15A 5kbwA-3iwjA:
undetectable		 5kbwA-3iwjA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 12 LEU A 476
ASP A 129
GLY A  71
LEU A  78
ALA A 173
 None
 1.41A 5kbwA-3iwjA:
undetectable		 5kbwA-3iwjA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND2_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 12 VAL A 155
ASP A 232
LEU A 206
ALA A 175
PRO A 151
 None
 1.25A 5nd2B-3iwjA:
undetectable		 5nd2B-3iwjA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3iwj PUTATIVE
AMINOALDEHYDE
DEHYDROGENASE
(Pisum
sativum) 		5 / 12 VAL A 155
ASP A 232
LEU A 206
ALA A 175
PRO A 151
 None
 1.27A 5syfB-3iwjA:
undetectable		 5syfB-3iwjA:
20.66