SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3iwr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GXS_A_BEZA601_0
(P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
A
P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
B)		 3iwr CHITINASE
(Oryza
sativa) 		4 / 7 GLY A 165
PRO A 163
ASP A 107
SER A 168
 None
 0.97A 1gxsA-3iwrA:
undetectable
1gxsB-3iwrA:
undetectable		 1gxsA-3iwrA:
20.95
1gxsB-3iwrA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3iwr CHITINASE
(Oryza
sativa) 		5 / 11 PHE A 121
ILE A 204
ALA A 241
LEU A 242
ALA A 124
 None
MES  A   1 (-4.6A)
None
None
None
 1.10A 1jb0B-3iwrA:
undetectable		 1jb0B-3iwrA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 3iwr CHITINASE
(Oryza
sativa) 		4 / 7 PHE A 147
ALA A 241
PHE A 238
SER A 237
 None
 1.29A 1lqtA-3iwrA:
undetectable		 1lqtA-3iwrA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 3iwr CHITINASE
(Oryza
sativa) 		3 / 3 ALA A 241
THR A 151
PHE A 128
 None
 0.56A 2c6nB-3iwrA:
undetectable		 2c6nB-3iwrA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3iwr CHITINASE
(Oryza
sativa) 		4 / 8 LEU A 102
ARG A 100
VAL A  93
ALA A 312
 None
 0.88A 3ax9A-3iwrA:
undetectable		 3ax9A-3iwrA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3iwr CHITINASE
(Oryza
sativa) 		5 / 11 PHE A 121
ILE A 204
ALA A 241
LEU A 242
ALA A 124
 None
MES  A   1 (-4.6A)
None
None
None
 1.10A 3pcqB-3iwrA:
undetectable		 3pcqB-3iwrA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3iwr CHITINASE
(Oryza
sativa) 		4 / 8 LEU A 102
ARG A 100
VAL A  93
ALA A 312
 None
 0.83A 3uniB-3iwrA:
undetectable		 3uniB-3iwrA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3iwr CHITINASE
(Oryza
sativa) 		5 / 9 THR A 247
ALA A 241
ALA A 218
ALA A 215
ILE A 219
 None
 1.11A 4lbgB-3iwrA:
undetectable		 4lbgB-3iwrA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 3iwr CHITINASE
(Oryza
sativa) 		4 / 8 GLY A 288
GLY A 287
HIS A 293
ASP A 296
 None
 0.72A 5f8yA-3iwrA:
undetectable		 5f8yA-3iwrA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 3iwr CHITINASE
(Oryza
sativa) 		4 / 8 GLY A 288
GLY A 287
HIS A 293
ASP A 296
 None
 0.71A 5f8yB-3iwrA:
undetectable		 5f8yB-3iwrA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_B_PQNB1844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3iwr CHITINASE
(Oryza
sativa) 		5 / 10 PHE A 121
ILE A 204
ALA A 241
LEU A 242
ALA A 124
 None
MES  A   1 (-4.6A)
None
None
None
 1.08A 5oy0b-3iwrA:
undetectable		 5oy0b-3iwrA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 3iwr CHITINASE
(Oryza
sativa) 		5 / 12 GLY A 279
PRO A 276
ALA A 275
THR A 282
VAL A 285
 None
MPD  A 341 (-4.8A)
None
None
MES  A   1 (-4.8A)
 1.21A 5x6yA-3iwrA:
undetectable		 5x6yA-3iwrA:
15.32