SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3iwz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_B_BEZB194_0
(PUTATIVE KINASE)		 3iwz CATABOLITE
ACTIVATION-LIKE
PROTEIN
(Xanthomonas
campestris) 		4 / 5 PRO A 131
ILE A 133
ARG A 132
ASP A 129
 None
 1.31A 2rhmB-3iwzA:
undetectable		 2rhmB-3iwzA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_D_BEZD194_0
(PUTATIVE KINASE)		 3iwz CATABOLITE
ACTIVATION-LIKE
PROTEIN
(Xanthomonas
campestris) 		4 / 5 PRO A 131
ILE A 133
ARG A 132
ASP A 129
 None
 1.40A 2rhmD-3iwzA:
undetectable		 2rhmD-3iwzA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 3iwz CATABOLITE
ACTIVATION-LIKE
PROTEIN
(Xanthomonas
campestris) 		4 / 6 ILE A 133
ARG A 132
LEU A  22
LEU A 126
 None
 0.99A 2rlfA-3iwzA:
undetectable
2rlfD-3iwzA:
undetectable		 2rlfA-3iwzA:
12.16
2rlfD-3iwzA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)		 3iwz CATABOLITE
ACTIVATION-LIKE
PROTEIN
(Xanthomonas
campestris) 		4 / 6 LEU A 196
GLN A 191
LEU A 193
GLU A 192
 None
 1.12A 3h5gB-3iwzA:
undetectable
3h5gC-3iwzA:
undetectable		 3h5gB-3iwzA:
9.91
3h5gC-3iwzA:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_0
(NEURAMINIDASE)		 3iwz CATABOLITE
ACTIVATION-LIKE
PROTEIN
(Xanthomonas
campestris) 		5 / 12 GLU A  88
LEU A 141
ARG A 144
ALA A 111
ARG A  98
 None
 1.48A 3k37B-3iwzA:
undetectable		 3k37B-3iwzA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 3iwz CATABOLITE
ACTIVATION-LIKE
PROTEIN
(Xanthomonas
campestris) 		4 / 5 VAL A 224
LEU A 217
LEU A 226
ILE A 164
 None
 0.94A 4a9jC-3iwzA:
undetectable		 4a9jC-3iwzA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 3iwz CATABOLITE
ACTIVATION-LIKE
PROTEIN
(Xanthomonas
campestris) 		3 / 3 ARG A 103
ARG A  42
ILE A  66
 None
 0.81A 4b7qC-3iwzA:
undetectable		 4b7qC-3iwzA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_A_CUA301_0
(E7)		 3iwz CATABOLITE
ACTIVATION-LIKE
PROTEIN
(Xanthomonas
campestris) 		4 / 5 HIS A 218
HIS A 180
GLN A 182
TYR A 227
 None
 1.24A 4gboA-3iwzA:
undetectable		 4gboA-3iwzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3iwz CATABOLITE
ACTIVATION-LIKE
PROTEIN
(Xanthomonas
campestris) 		5 / 12 LEU A  31
PHE A  30
ILE A  59
GLY A  83
VAL A  86
 None
 1.15A 4nkvC-3iwzA:
undetectable		 4nkvC-3iwzA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3iwz CATABOLITE
ACTIVATION-LIKE
PROTEIN
(Xanthomonas
campestris) 		5 / 12 LEU A  31
PHE A  30
ILE A  59
GLY A  83
VAL A  86
 None
 1.14A 4nkvD-3iwzA:
undetectable		 4nkvD-3iwzA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIZ_A_CUA301_0
(AA10A)		 3iwz CATABOLITE
ACTIVATION-LIKE
PROTEIN
(Xanthomonas
campestris) 		4 / 5 HIS A 218
HIS A 180
GLN A 182
TYR A 227
 None
 1.24A 5uizA-3iwzA:
undetectable		 5uizA-3iwzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3iwz CATABOLITE
ACTIVATION-LIKE
PROTEIN
(Xanthomonas
campestris) 		5 / 12 ILE A 133
ALA A 136
LEU A  22
ILE A 113
LEU A  91
 None
 0.97A 6a5yD-3iwzA:
undetectable		 6a5yD-3iwzA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3iwz CATABOLITE
ACTIVATION-LIKE
PROTEIN
(Xanthomonas
campestris) 		5 / 12 ILE A 133
ALA A 136
LEU A  22
ILE A 113
LEU A  91
 None
 0.98A 6a5zD-3iwzA:
undetectable		 6a5zD-3iwzA:
17.65